CRISPR News and Research

Latest CRISPR News and Research

Study provides new insight into how changes in DNA methylation contribute to diseases

More than half of our genome consists of transposons, DNA sequences that are reminiscent of ancient, extinct viruses.

19 Jul 2019

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

National Institute of Health researchers have reported the largest genomic study of type 2 diabetes in sub-Saharan Africans, with data from more than 5,000 individuals from Nigeria, Ghana and Kenya.

19 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model.

17 Jul 2019

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies.

15 Jul 2019

Study could lead to new strategies for slowing the growth of glioblastoma

Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a study published today in Cancer Research.

10 Jul 2019

Olympus Europe and Cytosurge join hands to accelerate drug development, single cell research

Olympus Europe and Cytosurge have partnered in order to accelerate common innovation of next-generation tools for single cell experiments and to expand the distribution of the versatile FluidFM BOT single cell research tool.

From Evident Corporation - Life Sciences 10 Jul 2019

New gene-editing protocol allows perfect mutation-effect matching

Geneticists have long awaited the ability to simply knock out or add a single gene here and there, as desired, with accuracy and efficiency, and then study the exact consequences caused by the loss or addition of that genetic information.

9 Jul 2019

Researchers capture high-resolution, 3D images of gene-editing enzymes

For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands.

9 Jul 2019

Mice cured of HIV in an experiment sparks new hope

HIV is a viral infection that leads to AIDS and is fatal in almost all cases. For decades now, researchers have been trying to find a complete cure for this infection that affects 37 million people across the globe.

4 Jul 2019

Researchers completely eliminate all traces of HIV from infected mice

For the first time, researchers have successfully removed HIV-1 DNA from the genomes of living animals, a critical step towards a potential cure for the disease.

4 Jul 2019

A non-coding RNA may play major role in memory formation

You could call this a neat discovery. Researchers at the University of Alabama at Birmingham have found that a tissue-specific, non-coding RNA called NEAT1 has a major, previously undescribed role in memory formation.

3 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

Researchers develop model of intestinal infection that could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It's the leading cause of waterborne disease from recreational waters in the United States.

21 Jun 2019

Research opens door to better treatment for common cause of diarrhea

One of the most common causes of diarrhea worldwide – accounting for millions of cases and tens of thousands of deaths, mostly of small children – is the parasiteCryptosporidium.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

FACS-based CRISPR screening shows how Chlamydia bacterium invades host cells

Using FACS-based CRISPR screening, scientists have identified three candidate genes that may facilitate the invasion of Chlamydia trachomatis into host cells.

19 Jun 2019

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

As part of its ongoing mission to advocate for researchers in the genomics age, Integrated DNA Technologies will unveil the latest additions to its NGS catalog to the European market at the European Human Genetics Conference in Gothenburg, Sweden on 15–18 June, 2019.

From Integrated DNA Technologies 13 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.