Cancer News and Research

Latest Cancer News and Research

Statins improves progression-free survival in patients with inflammatory breast cancer

Researchers from The University of Texas MD Anderson Cancer Center found statins, the commonly used drug to lower cholesterol, improved progression-free survival in patients with inflammatory breast cancer (IBC).

6 Dec 2012

Study finds relationships between body size and epigenetic changes

New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by ageing but are also affected by what we eat.

6 Dec 2012

SOX2 directly regulated by tumor suppressor CDKN1B(p27) gene

A team of researchers from the Spanish National Cancer Research Centre (CNIO), led by Manuel Serrano, from the Tumour Suppression Group, together with scientists from London and Santiago de Compostela, has discovered that the cellular reprogramming gene SOX2, which is involved in several types of cancers, such as lung cancer and pituitary cancer, is directly regulated by the tumor suppressor CDKN1B(p27) gene, which is also associated with these types of cancer.

6 Dec 2012

Scientists identify novel mechanism by which ketogenic diet could delay effects of aging

Scientists at the Gladstone Institutes have identified a novel mechanism by which a type of low-carb, low-calorie diet-called a "ketogenic diet"-could delay the effects of aging. This fundamental discovery reveals how such a diet could slow the aging process and may one day allow scientists to better treat or prevent age-related diseases, including heart disease, Alzheimer's disease and many forms of cancer.

6 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer

Bio-Path Holdings, Inc., a biotechnology company developing a liposomal delivery technology for nucleic acid cancer drugs, today announced it is initiating development of its lead cancer drug BP-100-1.01 (Liposomal Grb-2) to treat triple negative breast cancer (TNBC) and inflammatory breast cancer (IBC), two cancers characterized by formation of aggressive tumors and relatively high mortality rates.

6 Dec 2012

RedHill Biopharma completes $6.5M private placement

RedHill Biopharma Ltd., an Israeli biopharmaceutical company focusing primarily on development and acquisition of late clinical stage, patent-protected, new formulations and combinations of existing drugs, reported the completion of a private placement in a total amount of approximately $6.5 million.

6 Dec 2012

Scancell announces preliminary results from Part 1 of ImmunoBody vaccine Phase 1/2 MM trial

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, is pleased to announce preliminary results from Part 1 of the Phase 1/2 clinical trial of its DNA ImmunoBody vaccine in patients with Stage III/IV malignant melanoma.

6 Dec 2012

UC San Diego Health System receives Comprehensive Stroke Center designation

UC San Diego Medical Center-Hillcrest is one of five facilities in the country, and the only center in San Diego County, to be recognized as one of the first Comprehensive Stroke Centers (CSC), the newest level of certification for advanced stroke care awarded by The Joint Commission.

6 Dec 2012

First Edition: December 6, 2012

Today's headlines include a report that some in the GOP are urging lawmakers to support the idea of trading tax breaks for changes in safety-net programs.

6 Dec 2012

Patient-reported outcomes of head and neck surgery in focus

Researchers have taken the first step toward developing a new measure of health-related quality of life in people who have undergone head and neck reconstruction.

6 Dec 2012

Elderly cope better with oral cancer

Older individuals with oral squamous cell carcinoma report better health-related quality of life at one year after curative surgical treatment than do their younger counterparts, indicate UK study results.

6 Dec 2012

H. pylori colonic neoplasm link confirmed

Helicobacter pylori gastritis is significantly associated with colonic neoplasms, show the results of one of the largest studies of the association to date.

6 Dec 2012

Targeted therapy as common as chemotherapy at end of life

Targeted therapies are used as often as chemotherapy at the end of advanced cancer patients' lives, according to study results using US data.

6 Dec 2012

Using Nanoparticles to Target Cancer

An interview with John Stroh, discussing the development of nanoparticles that can target and treat cancer, without damaging nearby tissues.

6 Dec 2012

SLN surgery identifies whether breast cancer in lymph nodes remains after chemotherapy

Most patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. A study conducted through the American College of Surgeons Oncology Group and led by Judy Boughey, M.D. a breast surgeon at Mayo Clinic shows that a less invasive procedure known as sentinel lymph node surgery successfully identified whether cancer remained in lymph nodes in 91 percent of patients with node-positive breast cancer who received chemotherapy before their surgery.

6 Dec 2012

Combination of PD-991 and letrozole improves survival in patients with HER2- breast cancer

Pfizer Inc. today announced randomized Phase 2 data that showed PD-0332991 (PD-991) in combination with letrozole significantly extended progression free survival (PFS) compared with letrozole alone in post-menopausal patients with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or metastatic breast cancer.

6 Dec 2012

Alcoholics Anonymous helps men and women maintain sobriety in different ways

A new study finds differences in the ways that participation in Alcoholics Anonymous (AA) helps men and women maintain sobriety. Two Massachusetts General Hospital (MGH) investigators found that, while many factors are helpful to all AA participants, some were stronger in men and some in women.

6 Dec 2012

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

Marking a major milestone in what has become a fast-growing standard of care in prostate cancer surgery, the chief of urologic oncology at The Cancer Institute of New Jersey has completed his 1,000th robotic prostatectomy at Robert Wood Johnson University Hospital (RWJUH), the Flagship Hospital of The Cancer Institute of New Jersey, which is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.

6 Dec 2012

Bisphenol A blocks calcium channels in cell membranes

Bisphenol A, a substance found in many synthetic products, is considered to be harmful, particularly, for fetuses and babies. Researchers from the University of Bonn have now shown in experiments on cells from human and mouse tissue that this environmental chemical blocks calcium channels in cell membranes. Similar effects are elicited by drugs used to treat high blood pressure and cardiac arrhythmia. The results are now presented in the journal "Molecular Pharmacology."

6 Dec 2012