Cancer News and Research

Latest Cancer News and Research

Lawson researchers exploit hunger hormone to identify prostate cancer

Non-invasive imaging detects prostate cancer earlier than ever before, but can't accurately distinguish between malignant and benign disease. According to Lawson Health Research Institute's Drs. John Lewis and Len Luyt, a new molecular imaging probe could be the answer.

9 Dec 2011

Positive results from Synta's Ganetespib Phase 2 trial on HER2-positive and triple negative mBC

Synta Pharmaceuticals Corp. - Ganetespib, a potent, second generation Hsp90 inhibitor, has demonstrated clinical activity in heavily pre-treated patients with HER2-positive and triple negative metastatic breast cancer according to Phase 2 clinical trial results presented by researchers from Memorial Sloan-Kettering Cancer Center at the San Antonio Breast Cancer Symposium.

9 Dec 2011

Combination of MEK inhibitors and nilotinib can overcome CML resistance to targeted drug

Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according to research published in Cancer Cell today.

9 Dec 2011

Scientists uncover three new locations for Crohn's Disease genes

Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach.

9 Dec 2011

USPTO issues Diabetes Patent to Omni Bio

Omni Bio Pharmaceutical, Inc. today announced that U.S. Patent No. 8,071,551, entitled "METHODS AND COMPOSITIONS FOR TREATING DIABETES," was issued by the United States Patent and Trademark Office on December 6, 2011. The Diabetes Patent expires in May 2022.

9 Dec 2011

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed an agreement with Pharmacyclics, Inc. to jointly develop and market the anti-cancer compound, PCI-32765.

9 Dec 2011

Toxins in Danish mushroom are effective against cancer cells

Researchers at the University of Copenhagen have explored the active principles of a Danish mushroom and found that some of the substances it contains are particularly toxic towards cancer cells. The goal is to synthesise and refine substances in the mushroom that may be useful in future drug development.

9 Dec 2011

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

ChemoCentryx commences CCX140 Phase II trial in diabetic nephropathy

ChemoCentryx, Inc. today announced the initiation of a Phase II clinical trial for CCX140, an orally-administered small molecule for the treatment of diabetic kidney disease.

9 Dec 2011

FDA advisory panel OKs anemia drug peginesatide

Once approved by the FDA, the once-monthly injection could capture a share of the $3 billion U.S. market for anemia drugs used for kidney dialysis patients, currently dominated by Amgen Inc's blockbuster Epogen. Affymax, which developed the drug with partner Takeda Pharmaceutical Co Ltd, is also expected to price its product below Epogen.

8 Dec 2011

Breast cancer risks and management updates

A new report that looks at the environmental factors that affect risk of breast cancer is out. It suggests that women can reduce their risk by avoiding unnecessary medical radiation, forgoing hormone treatments for menopause that combine estrogen and progestin, limiting alcohol intake and minimizing weight gain.

8 Dec 2011

Race, ethnicity, and insurance status influence follow-up care

According to the results of a new study published in the Journal of the American College of Surgeons, African-Americans, Hispanics and uninsured patients use fewer post-hospitalization services after traumatic injury, including home health care, skilled nursing care, and rehabilitation.

8 Dec 2011

Study contradicts premise of framing effect on making health decisions

The behavior of consumers who are faced with making decisions about their health is not significantly influenced by the way health messages are worded or framed, according to a large, new study by researchers at the University at Buffalo and other institutions.

8 Dec 2011

Study raises questions about breast cancer therapy

The study, which looked at Medicare records of more than 130,000 women, found that those who underwent the faster treatment, called brachytherapy, were about twice as likely to have a mastectomy in the following five years -

8 Dec 2011

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

The addition of zoledronic acid to adjuvant endocrine therapy increased bone mineral density and reduced the risk for disease recurrence among postmenopausal women with early hormone receptor-positive breast cancer, according to new data from the ZO-FAST trial.

8 Dec 2011

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

The vast majority of genetic disorders (schizophrenia or breast cancer, for example) have different effects in different people. Moreover, an individual carrying certain mutations can develop a disease, whereas another one with the same mutations may not. This holds true even when comparing two identical twins who have identical genomes. But why does the same mutation have different effects in different individuals?

8 Dec 2011

H. pylori bacterium produces urease to neutralize gastric acid

A research team led by scientists at the Chinese University of Hong Kong is releasing study results this week showing how a bacterium, Helicobacter pylori, that causes more than half of peptic ulcers worldwide and that has been implicated in stomach cancer has managed for eons to turn the acidic environment of the human gut into one in which it can thrive.

8 Dec 2011

Ixabepilone-sunitinib combination holds potential against chemotherapy-resistant ovarian cancer

The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.

8 Dec 2011

Heart patients may experience fewer traumas with new invention

Heart patients may experience "a lot less" trauma with a new invention to mend leaky valves with minimum cutting, says inventor James Gammie, MD, an associate professor at the University of Maryland (UM) School of Medicine.

8 Dec 2011

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns. In a report to appear in the December Journal of Experimental Medicine, members of a nationwide research collaborative describe the initial results of their investigation into the immune system response to serious injury, findings which have overturned some longstanding assumptions.

8 Dec 2011

Cancer News and Research

Latest Cancer News and Research

Lawson researchers exploit hunger hormone to identify prostate cancer

Positive results from Synta's Ganetespib Phase 2 trial on HER2-positive and triple negative mBC

Combination of MEK inhibitors and nilotinib can overcome CML resistance to targeted drug

Scientists uncover three new locations for Crohn's Disease genes

USPTO issues Diabetes Patent to Omni Bio

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Toxins in Danish mushroom are effective against cancer cells

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

ChemoCentryx commences CCX140 Phase II trial in diabetic nephropathy

FDA advisory panel OKs anemia drug peginesatide

Breast cancer risks and management updates

Race, ethnicity, and insurance status influence follow-up care

Study contradicts premise of framing effect on making health decisions

Study raises questions about breast cancer therapy

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

H. pylori bacterium produces urease to neutralize gastric acid

Ixabepilone-sunitinib combination holds potential against chemotherapy-resistant ovarian cancer

Heart patients may experience fewer traumas with new invention

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Understanding the DNA Damage Response in Innate Immunity eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Cancer News and Research

Latest Cancer News and Research

Understanding the DNA Damage Response in Innate Immunity eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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