Cancer News and Research

Latest Cancer News and Research

Positive results from RXi's sd-rxRNA technology for development of novel therapeutics

RXi Pharmaceuticals Corporation, a recognized leader in RNAi-based therapeutics, announced today that, as part of its collaboration with miRagen Therapeutics, positive data were generated demonstrating that RXi's sd-rxRNA technology can be used, in vitro, to specifically enhance the activity of a microRNA of high interest to miRagen.

28 Jan 2011

Gene signature can accurately predict breast cancer outcomes

Researchers from McGill University's Rosalind and Morris Goodman Cancer Research Centre, the Research Institute of the McGill University Health Centre, the Dana-Farber Cancer Institute and Harvard Medical School have discovered a gene signature that can accurately predict which breast cancer patients are at risk of relapse, thereby sparing those who are not from the burdens associated with unnecessary treatment.

28 Jan 2011

Aging-associated protein deficiency may lead to positive breast cancer in women

The most common type of breast cancer in older women - estrogen and progesterone receptor positive breast cancer - has been linked to a protein that fends off aging-related cellular damage.

28 Jan 2011

Iniparib Phase III study in metastatic triple-negative breast cancer does not meet primary goal

Sanofi-aventis and its subsidiary, BiPar Sciences, today announced that a randomized Phase III trial evaluating iniparib (BSI-201) in patients with metastatic triple-negative breast cancer (mTNBC) did not meet the pre-specified criteria for significance for co-primary endpoints of overall survival and progression-free survival

28 Jan 2011

Provectus announces completion of PV-10 Phase 1 trial in patients with liver cancer

Provectus Pharmaceuticals, a development-stage oncology and dermatology biopharmaceutical company, has completed patient accrual and treatment of all subjects in its Phase 1 clinical trial of PV-10 for liver cancer.

27 Jan 2011

H3 Biomedicine introduces cancer research and development operations in Cambridge

H3 Biomedicine today announced that it has launched research and development operations in Cambridge, Massachusetts. H3 Biomedicine will undertake a comprehensive approach to breakthrough oncology treatments based on two primary principles: 1) the genetics of patients' cancers can reveal drug targets tailored to their cancers and 2) the advances in modern chemistry enable the discovery of new classes of safe and effective drugs against these targets.

27 Jan 2011

Plexxikon begins PLX5622 Phase 1 trial in patients with rheumatoid arthritis

Plexxikon today announced that dosing began in the first of two Phase 1 clinical trials with PLX5622, a novel, oral and highly selective Fms inhibitor, targeted for the treatment of rheumatoid arthritis.

27 Jan 2011

NHS reforms & proposed spending questioned

According to John Appleby, Chief Economist at the King’s Fund, deaths from heart attacks and cancer in the UK are falling despite lower spending on health than in countries such as France. This, he said calls attention to the Government’s claim that poor outcomes justify a £1.4 billion restructuring of the NHS that will pass control of budgets from managers to GPs. He said, “Comparing health outcomes across countries is complex and not simply down to healthcare spending, but these trends must challenge one of the government’s key justifications for reforming the NHS.”

27 Jan 2011

Showman surgeon in an ethical tangle

Dr. Charlie Teo had stirred the hornet’s nest of ethical issues by offering to allow a person to spend a day in his company, including the possibility of watching his intricate excision of brain tumors, as a prize in a charity auction held at the Concord Function Centre to raise funds for childhood cancer research. The prize fetched about $1,500.

27 Jan 2011

Major changes at Journal of Vascular and Interventional Radiology

The Journal of Vascular and Interventional Radiology-the monthly, peer-reviewed flagship publication of the Society of Interventional Radiology-announced several major changes for 2011-all directed at highlighting the global impact of this minimally invasive medical specialty and its lead journal.

27 Jan 2011

St. Michael's Hospital to build first automated high-throughput zebrafish screening facility in Canada

Zebrafish are the new fruit flies.

27 Jan 2011

GE to establish Global Pathology Imaging Centre of Excellence in Ontario

GE announced an agreement to establish its first Global Pathology Imaging Centre of Excellence in Toronto, Ontario. GE and its digital pathology joint venture, Omnyx™, will invest $7.75M along with a $2.25M grant from the Health Technology Commercialization Program created by HTX and funded by the Ontario Ministry of Research and Innovation.

27 Jan 2011

TD2 and Flagship Biosciences offer combined oncology and pathology services

TGen Drug Development (TD2) and Flagship Biosciences today announced a strategic alliance that should help speed new drugs safely into human testing and quickly benefit cancer patients.

27 Jan 2011

DMP1 protein prevents endothelial cells to respond to VEGF

A team from the Metastasis Research Laboratory (GIGA-Cancer/Liège University Hospital) has just published, in the prestigious journal BLOOD, their work demonstrating that the DMP1 protein has previously unsuspected anti-angiogenic activities which could be used for the development of new treatments against cancer, but also against diseases in which angiogenesis plays a major role, such as psoriasis, rheumatoid arthritis or diabetic retinopathy.

27 Jan 2011

ASTRO continues commitment to 6-point patient protection plan

The American Society for Radiation Oncology is continuing its commitment to Target Safely, a six-point patient protection plan developed in January 2010, to improve the safety and quality of radiation therapy treatments and reduce the chances of medical errors.

27 Jan 2011

Fibroblasts help 'recruit' immune cells for tumor growth

The most common connective tissue cell in animals is the fibroblast, which plays an important role in healing wounds. But Dr. Neta Erez of Tel Aviv University's Sackler Faculty of Medicine has now demonstrated that fibroblasts can also do a body great harm, helping to "recruit" immune cells for tumor growth.

27 Jan 2011

Nanoencapsulation helps administer more-effective doses of anti-cancer drugs

Scientists are reporting successful application of the technology used in home devices to clean jewelry, dentures, and other items to make anticancer drugs like tamoxifen and paclitaxel dissolve more easily in body fluids, so they can better fight the disease. The process, described in ACS' journal, Langmuir, can make other poorly soluble materials more soluble, and has potential for improving the performance of dyes, paints, rust-proofing agents and other products.

27 Jan 2011

FDA approves Corindus CorPath 200 System for pivotal trial to evaluate safety, effectiveness

Corindus Vascular Robotics, a leading developer of precision vascular robotics, today announced it has been granted Food and Drug Administration conditional Investigational Device Exemption approval to evaluate the safety and effectiveness of its CorPath® 200 System in delivering and manipulating coronary guidewires and stent/balloon systems in percutaneous coronary interventions procedures.

27 Jan 2011

AB Science initiates recruitment in masitinib phase 3 study in severe persistent asthma

AB Science SA, a pharmaceutical company specialising in the research, development and commercialisation of protein kinase inhibitors (PKIs), announced today the recruitment of the first patient in the phase 3 study evaluating masitinib in severe persistent asthma.

27 Jan 2011

How estrogen decreases risk and delays onset and progression of Alzheimer's disease

An influential article in the journal Progress in Neurobiology provided one of the first comprehensive reviews of how estrogen potentially can protect against Alzheimer's disease and other neurological disorders.

27 Jan 2011

Cancer News and Research

Latest Cancer News and Research

Positive results from RXi's sd-rxRNA technology for development of novel therapeutics

Gene signature can accurately predict breast cancer outcomes

Aging-associated protein deficiency may lead to positive breast cancer in women

Iniparib Phase III study in metastatic triple-negative breast cancer does not meet primary goal

Provectus announces completion of PV-10 Phase 1 trial in patients with liver cancer

H3 Biomedicine introduces cancer research and development operations in Cambridge

Plexxikon begins PLX5622 Phase 1 trial in patients with rheumatoid arthritis

NHS reforms & proposed spending questioned

Showman surgeon in an ethical tangle

Major changes at Journal of Vascular and Interventional Radiology

St. Michael's Hospital to build first automated high-throughput zebrafish screening facility in Canada

GE to establish Global Pathology Imaging Centre of Excellence in Ontario

TD2 and Flagship Biosciences offer combined oncology and pathology services

DMP1 protein prevents endothelial cells to respond to VEGF

ASTRO continues commitment to 6-point patient protection plan

Fibroblasts help 'recruit' immune cells for tumor growth

Nanoencapsulation helps administer more-effective doses of anti-cancer drugs

FDA approves Corindus CorPath 200 System for pivotal trial to evaluate safety, effectiveness

AB Science initiates recruitment in masitinib phase 3 study in severe persistent asthma

How estrogen decreases risk and delays onset and progression of Alzheimer's disease

Understanding the DNA Damage Response in Innate Immunity eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Cancer News and Research

Latest Cancer News and Research

Understanding the DNA Damage Response in Innate Immunity eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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