Cancer News and Research

Latest Cancer News and Research

Researchers define genetic landscape of uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Research explores sex differences in placental defenses against SARS-CoV-2 infection

A plethora of earlier studies has reported on the differences between the sexes in susceptibility to the currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as its severity. A new preprint research paper posted to the bioRxiv* server extends this to the placenta in pregnancy.

6 Apr 2021

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

Despite guidelines, end-of-life care remains aggressive for ovarian cancer patients

People with ovarian cancer frequently receive aggressive end-of-life care despite industry guidelines that emphasize quality of life for those with advanced disease, according to a recent study.

6 Apr 2021

Women experienced high rates of mental health problems early in COVID-19 pandemic

A study at the University of Chicago Medicine found U.S. women experienced increased incidence of health-related socioeconomic risks (HRSRs), such as food insecurity and interpersonal violence, early in the COVID-19 pandemic.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

Cavity shave margin resection reduces the rate of positive margins in patients with DCIS

According to the American Cancer Society, a noninvasive breast cancer called ductal carcinoma in situ (DCIS) accounts for approximately one of every four new breast cancer cases in the United States.

5 Apr 2021

Deep learning algorithms improve diagnostic performance of breast ultrasound

Ultrasound is widely used to detect breast cancer early, but misdiagnosis of benign lesions as malignant tumors sometimes leads to unnecessary biopsies.

5 Apr 2021

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor (TCR) sequencing data. T-cell receptors are found on the surface of immune T cells.

5 Apr 2021

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Maternal exposure to pesticides may lead to central nervous system tumors during childhood

Research published in the peer-reviewed journal Environmental Research suggests that exposure during pregnancy to a wide variety of pesticides may lead to the development of central nervous system tumors during childhood.

3 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Researchers in Italy have identified a pair of microRNA molecules that help maintain a population of cancerous stem cells that drive the growth of breast cancers and initiate tumor relapse after treatment.

3 Apr 2021

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.

3 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has long studied neglected tropical diseases -- chronic and disabling parasitic infections that primarily affect poor and underserved communities in developing nations.

3 Apr 2021

50-state analysis finds excess deaths from COVID-19 and other causes in the U.S.

Extended surges in the South and West in the summer and early winter of 2020 resulted in regional increases in excess death rates, both from COVID-19 and from other causes, a 50-state analysis of excess death trends has found.

3 Apr 2021

Cancer News and Research

Latest Cancer News and Research

Researchers define genetic landscape of uterine leiomyosarcomas

Research explores sex differences in placental defenses against SARS-CoV-2 infection

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Despite guidelines, end-of-life care remains aggressive for ovarian cancer patients

Women experienced high rates of mental health problems early in COVID-19 pandemic

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

New RNA-sequencing method can help detect numerous modified small RNAs

High expression of cell death genes may increase risk of early death from lung cancer

Cavity shave margin resection reduces the rate of positive margins in patients with DCIS

Deep learning algorithms improve diagnostic performance of breast ultrasound

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Maternal exposure to pesticides may lead to central nervous system tumors during childhood

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

50-state analysis finds excess deaths from COVID-19 and other causes in the U.S.

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