Cancer News and Research

Latest Cancer News and Research

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Too many "exhausted" T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job.

16 Aug 2021

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Scientists at the National Institutes of Health (NIH) have developed a new sample preparation method to detect SARS-Cov-2, the virus that causes COVID-19.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

Removing race as a factor in a kidney function-estimating equation used to guide cancer treatment dosing and eligibility may decrease the proportion of Black patients recommended to receive full doses of anticancer drugs.

16 Aug 2021

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Scientists with the Ajmera Transplant Centre at UHN have conducted a first-in-the-world randomized placebo-controlled trial of third dose COVID-19 booster vaccine for transplant patients that shows substantially improved protection.

14 Aug 2021

Study helps to clarify the post-clinical trial needs of cancer patients

Cancer clinical trials (CCTs) provide patients an opportunity to receive experimental drugs, tests, and/or procedures that can lead to remissions. For some, a CCT may seem like their only option. Yet little is known about the experiences of patient participants who withdraw from CCTs.

14 Aug 2021

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

An accurate assessment of a patient's kidney function is critical for determining eligibility for anticancer treatments.

14 Aug 2021

Simple roundworm may hold the key to understanding cell death processes

A biologist at The University of Texas at Arlington hopes that a simple roundworm might hold the key to understanding novel cell death processes. Such knowledge could lead to improved therapies to treat a variety of conditions in humans, including cancer and neurological injuries.

14 Aug 2021

Enzyme acts as a sensor to find the hiding spots of viruses

While some types of RNA viruses cloak themselves to hide inside a cell and create copies of themselves, a "detective enzyme" might be attuned to their whereabouts. A slight variation in their genomic code gives some people's cells the capacity to produce this sensor.

14 Aug 2021

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A - a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection - is controlled.

13 Aug 2021

Structure of BRCA2 protein complex critical for DNA repair solved

The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA.

13 Aug 2021

‘I don’t want to risk my life for a paycheck’: Immunosuppressed people grapple with returning to work

Elizabeth Groenweghe got a kidney transplant 14 years ago. She now takes several medications to prevent her body from rejecting her transplant organ. But these medications also weaken her immune system, putting her at higher risk of becoming seriously ill if she catches covid-19.

13 Aug 2021

Study finds durable responses to immunotherapy in rare angiosarcomas

In a small study of 16 patients with the rare cancer angiosarcoma, tumors in four patients partially or completely responded to treatment with a combination of the immunotherapy drugs ipilimumab and nivolumab.

13 Aug 2021

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

In a recent study published in Cancer Research, researchers from Fels Cancer Institute for Personalized Medicine at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center identified specific leukemia gene mutations and the mechanisms by which they regulate DNA repair and respond to PARP inhibitors.

13 Aug 2021

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells.

13 Aug 2021

Study examines the relationship between air pollution and labor productivity

Recent studies have highlighted the link between high levels of air pollution and poor health; for example, even short exposure to air pollutants can increase the risk of respiratory infections, heart disease and even lung cancer.

13 Aug 2021

Study uncovers a subset of human short introns spliced out by a distinct mechanism

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins.

13 Aug 2021

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Today, I signed CDC's Advisory Committee on Immunization Practices' (ACIP) recommendation that endorsed the use of an additional dose of COVID-19 vaccine for people with moderately to severely compromised immune systems after an initial two-dose vaccine series.

13 Aug 2021

Study finds comparatively less marijuana use in cancer patients than the general public

Last month, three states – Virginia, South Dakota, and Connecticut – joined the ranks of more than a dozen others that have legalized marijuana – also known as cannabis – for recreational use. Yet, despite these changing laws and growing social acceptance of the drug, a new study finds that use is still lower among cancer patients.

13 Aug 2021

Cancer News and Research

Latest Cancer News and Research

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Study helps to clarify the post-clinical trial needs of cancer patients

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

Simple roundworm may hold the key to understanding cell death processes

Enzyme acts as a sensor to find the hiding spots of viruses

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

Structure of BRCA2 protein complex critical for DNA repair solved

‘I don’t want to risk my life for a paycheck’: Immunosuppressed people grapple with returning to work

Study finds durable responses to immunotherapy in rare angiosarcomas

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Study examines the relationship between air pollution and labor productivity

Study uncovers a subset of human short introns spliced out by a distinct mechanism

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Study finds comparatively less marijuana use in cancer patients than the general public

Industry Focus eBook - Oncology (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Cancer News and Research

Latest Cancer News and Research

Industry Focus eBook - Oncology (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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