Chemotherapy News and Research

Latest Chemotherapy News and Research

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer.

5 Jun 2021

New technology predicts effectiveness of chemotherapy after one treatment

While early detection of breast cancer is critical, early prediction of how well the neoadjuvant chemotherapy treatment before surgery is working also may provide a window of opportunity when treatment could be altered and have a big impact on the patient's quality of life.

4 Jun 2021

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Aging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1.

3 Jun 2021

New class of hydrogels can enable precise drug delivery

Hydrogels are commonly used inside the body to help in tissue regeneration and drug delivery. However, once inside, they can be challenging to control for optimal use. A team of researchers in the Department of Biomedical Engineering at Texas A&M University is developing a new way to manipulate the gel -- by using light.

3 Jun 2021

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Oncotarget published "A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas" which reported that the incidence of human papillomavirus-positive head and neck squamous cell carcinoma has increased dramatically over the past decades due to an increase in infection of the oral mucosa by HPV.

3 Jun 2021

NIH supports a new strategy to reduce side effects of head and neck cancer treatment

A new strategy to reduce the side effects suffered by patients undergoing treatment for head and neck cancers now has the support of the National Institutes of Health.

2 Jun 2021

Researchers discover gene that impacts the development of Ewing sarcoma in children

Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children.

1 Jun 2021

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

Moffitt Cancer Center, a national leader in cancer care and research and the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, is presenting new data from dozens of clinical research studies at this year's American Society of Clinical Oncology (ASCO) Annual Meeting, the world's largest clinical cancer research meeting.

1 Jun 2021

Study could help identify risk of secondary leukaemia in certain children

Scientists from the Wellcome Sanger Institute and the University of Cambridge found that in children with neuroblastoma - a cancer of immature nerve cells - treatment with platinum chemotherapy caused changes to the genome that could then cause leukaemia in some children later on.

31 May 2021

New study may help improve stem cell transplantation, lead to better drugs

Your immune system is always busy fighting incoming threats. It consists of a system of cells, and when there is a shortage of cells, it affects the performance of the immune system.

29 May 2021

FDA approves targeted therapy for tumors with KRAS mutations

Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy.

29 May 2021

Platinum chemotherapy can cause leukaemia in children with neuroblastoma, shows study

New research indicates that certain anti-cancer therapies may hasten cellular aging, where changes in the DNA of patients may contribute to greater inflammation and fatigue. The findings are published by Wiley early online in CANCER, a peer-reviewed journal of the American Cancer Society.

29 May 2021

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body.

28 May 2021

New biomarker could be used to determine resistance of ovarian cancer to platinum chemotherapy

Epithelial ovarian cancer (EOC) is the most common lethal gynaecological cancer. Ovarian cancer is usually treated with platinum-based chemotherapy; however, a significant number of patients are resistant to such treatments and relapse soon afterwards.

28 May 2021

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Antibodies aren't the only immune cells needed to fight off COVID-19 - T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine.

27 May 2021

New technique using "soft" X-rays offers a simpler way to gain insight into nanocarriers

Before the huge potential of tiny nanocarriers for highly targeted drug delivery and environmental clean-up can be realized, scientists first need to be able to see them.

25 May 2021

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

By 2030, pancreatic ductal adenocarcinoma (PDAC), the most lethal form of pancreatic cancer, is projected to become the second leading cause of cancer-related deaths in the United States.

24 May 2021

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

21 May 2021

Adaptimmune to report Phase 2 trial data on synovial sarcoma at ASCO congress

Adaptimmune Therapeutics plc, a leader in cell therapy to treat cancer, will report initial data from its Phase 2 SPEARHEAD-1 trial, with afamitresgene autoleucel (afami-cel, formerly ADP-A2M4), at the American Society of Clinical Oncology (ASCO) congress. Full abstracts were released online today.

21 May 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

Chemotherapy News and Research

Latest Chemotherapy News and Research

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

New technology predicts effectiveness of chemotherapy after one treatment

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

New class of hydrogels can enable precise drug delivery

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

NIH supports a new strategy to reduce side effects of head and neck cancer treatment

Researchers discover gene that impacts the development of Ewing sarcoma in children

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

Study could help identify risk of secondary leukaemia in certain children

New study may help improve stem cell transplantation, lead to better drugs

FDA approves targeted therapy for tumors with KRAS mutations

Platinum chemotherapy can cause leukaemia in children with neuroblastoma, shows study

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

New biomarker could be used to determine resistance of ovarian cancer to platinum chemotherapy

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

New technique using "soft" X-rays offers a simpler way to gain insight into nanocarriers

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Adaptimmune to report Phase 2 trial data on synovial sarcoma at ASCO congress

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

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Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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