Chemotherapy News and Research

Latest Chemotherapy News and Research

A new model for assessing kidney function in cancer patients

Cold Spring Harbor Laboratory scientists have developed a new model for assessing kidney function in cancer patients as part of an international collaboration that involved contributions from the United Kingdom and Sweden.

10 Dec 2020

Mastectomy and reconstructive surgery may increase risk of becoming persistent drug users

Women who receive mastectomy and reconstructive surgery as part of breast cancer treatment may face the risk of developing persistent use of opioids and sedative-hypnotic drugs, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Breast cancer survivors less likely to get pregnant than the general population

A large meta-analysis of breast cancer survivors of childbearing age indicated that they are less likely than the general public to get pregnant, and they face higher risk of certain complications such as preterm labor.

9 Dec 2020

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

After a median follow-up of 5.1 years, among women with lymph node-positive early-stage breast cancer and a recurrence score of 25 or lower who received adjuvant endocrine therapy with or without chemotherapy, postmenopausal patients had no added benefit from chemotherapy, while premenopausal patients who received chemotherapy had improved invasive disease-free survival (IDFS) and an early indication of improved overall survival (OS), according to data from the SWOG S1007 RxPONDER clinical trial presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Researchers say they've identified a way to disrupt a process that promotes the growth of pancreatic cancers -- one of the most difficult and deadly cancers to treat.

9 Dec 2020

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Early study data shows a 29% overall response rate, the favorable safety profile in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

8 Dec 2020

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Novel menin-KMT2A inhibitor appears to be safe and well-tolerated. FLT3 inhibitor plus low-dose chemotherapy shows promising efficacy and safety. Results represent encouraging news on hard-to-treat AML subtypes.

7 Dec 2020

Study reveals low detection of SARS-CoV-2 on environmental surfaces across oncology settings

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

7 Dec 2020

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Roswell Park Comprehensive Cancer Center's Francisco J. Hernandez-Ilizaliturri, MD, along with a team of researchers from other institutions, has been investigating a novel therapy for patients with relapsed or refractory B-cell non-Hodgkin lymphoma.

7 Dec 2020

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.

7 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

7 Dec 2020

Obesity linked to mortality gap between Black and white women with early breast cancer

In an analysis of women with early breast cancer, Black women had higher rates of obesity and other health conditions that can affect survival, compared with white women.

7 Dec 2020

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a "zombie" cell state called senescence, Medical College of Georgia scientists report.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

New tool to predict breast cancer recurrences

A new tool combining traditional pathology with machine learning could predict which breast cancer patients actually need surgery.

3 Dec 2020

Chemotherapy News and Research

Latest Chemotherapy News and Research

A new model for assessing kidney function in cancer patients

Mastectomy and reconstructive surgery may increase risk of becoming persistent drug users

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Breast cancer survivors less likely to get pregnant than the general population

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

Repair protein may prevent damage to healthy cells during cancer therapy

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Study reveals low detection of SARS-CoV-2 on environmental surfaces across oncology settings

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

Obesity linked to mortality gap between Black and white women with early breast cancer

Targeting senescent 'zombie' cells may improve survival in women with cervical cancer

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

New tool to predict breast cancer recurrences

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Chemotherapy News and Research

Latest Chemotherapy News and Research

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Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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