Chemotherapy News and Research

Latest Chemotherapy News and Research

Study identifies promising cancer target for liposarcoma

A study conducted by a team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed a close association between liposarcoma (LPS), a type of cancer that develops from fat cells, and the bromodomain and extraterminal (BET) protein family.

3 Jun 2019

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment.

3 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

International clinical study of new drug to treat advanced prostate cancers yields promising results

Today the New England Journal of Medicine published the first results of a phase III international clinical study called TITAN (National Clinical Trials Number 02489318), which evaluated the effectiveness and safety of a new drug, apalutamide, to treat advanced prostate cancers.

3 Jun 2019

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

A new approach to predict complications after surgery for patients with larynx cancer

A technique that illuminates blood flow during surgery predicted which head and neck cancer patients were likely to have issues with wound healing. It could enable surgeons to make adjustments during surgery or recovery to improve outcomes.

31 May 2019

Tumor-fighting combination targets aggressive form of brain cancer

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

31 May 2019

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

A method of growing blood stem cells in the laboratory has been developed by researchers at Stanford University and the University of Tokyo, in a breakthrough that could spare some people with blood and immune disorders from the side effects of intensive chemotherapy and radiotherapy.

31 May 2019

Research provides new options for treatment of multi-drug resistant infections

A new study, published in 'Antimicrobial Agents and Chemotherapy' conducted by a University of Liverpool led research consortium, has helped develop a new treatment option for some multi-drug resistant infections.

30 May 2019

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia, have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center.

30 May 2019

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1.

29 May 2019

Surgery can be beneficial for one type of primary central nervous system lymphoma

Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed.

From Johns Hopkins Medicine 29 May 2019

PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Seven innovative research projects tackling pancreatic cancer have been awarded grants totalling £1.2M by the UK medical research charity, Pancreatic Cancer Research Fund.

28 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

A final comfort: ‘Palliative transport’ brings dying children home

Anne Brescia sat beside her only child, Anthony, as he lay unconscious in a hospital bed at age 16. Just a few months before, he was competing in a swim meet; now cancer was destroying his brain. Brescia couldn’t save her son. But she was determined to bring him home.

28 May 2019

Chemotherapy News and Research

Latest Chemotherapy News and Research

Study identifies promising cancer target for liposarcoma

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

International clinical study of new drug to treat advanced prostate cancers yields promising results

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

A new approach to predict complications after surgery for patients with larynx cancer

Tumor-fighting combination targets aggressive form of brain cancer

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

Research provides new options for treatment of multi-drug resistant infections

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Surgery can be beneficial for one type of primary central nervous system lymphoma

PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Researchers discover unexpected survival mechanism of a subset of cancer cells

A final comfort: ‘Palliative transport’ brings dying children home

Study: One-third of pancreatic cancer patients miss out on treatment that may extend survival

Starving the fungus could help fight drug-resistant fungal infections

Benefit of allogeneic stem cell transplantation in non-Hodgkin lymphoma remains unclear

Cancer Research - Second Edition eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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