Chemotherapy News and Research

Latest Chemotherapy News and Research

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

Even with equivalent treatments in women with hormone receptor-positive, HER2-negative breast cancer, black women had significantly higher breast cancer recurrence and increased overall mortality compared to white women in a large phase III clinical trial, TAILORx, according to data presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8.

7 Dec 2018

New technology for profiling genetic makeup of myeloma tumor cells developed

Cancer arises when cells lose control. Deciphering the "blueprint" of cancer cells - outlining how cancer cells hijack specific pathways for uncontrolled proliferation - will lead to more efficient ways to fight it.

7 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Lymph node ratio could predict survival in patients with oral cavity cancer

Five years after diagnosis, only 40 percent of patients with locally-advanced oral cavity cancer will still be alive. The question is who is likely to live and who is likely to die? The answer to this question could not only help patients better predict the course of their disease, but could help doctors choose the most appropriate post-surgical treatments - patients at highest risk could receive the most aggressive combinations of radiation and chemotherapy.

6 Dec 2018

Breast cancer treatment more effective when determined by tumor cell count

Research published today shows that circulating tumor cell count may provide an effective indicator of appropriate treatment choice for metastatic breast cancer.

6 Dec 2018

Study: Chemotherapy agent did not improve survival in patients with triple-negative breast cancer

Treating patients who had early-stage triple-negative breast cancer with the chemotherapy agent capecitabine after they completed surgery and standard chemotherapy did not significantly improve disease-free or overall survival compared with observation, according to data from the randomized, phase III GEICAM/CIBOMA clinical trial presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8.

6 Dec 2018

Researchers develop biosensors to detect and measure metastatic potential of cancer cells

The spread of invasive cancer cells from a tumor's original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience, University of California San Diego School of Medicine researchers reported engineering sensors that can detect and measure the metastatic potential of single cancer cells.

6 Dec 2018

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

A new article published today in The Lancet Oncology shows 39 percent of large B cell lymphoma patients treated with the chimeric antigen receptor T-cell therapy Yescarta remained in remission more than two years following therapy, and more than half of the patients treated remain alive.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

UK scientists find new way to identify patients with aggressive lymphoma

UK scientists have found a new way to identify people with the most aggressive types of lymphoma who are less likely to respond to standard drugs.

3 Dec 2018

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

More than 30 abstracts presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, December 1-4, featured research highlighting the ability of Bio-Rad's Droplet Digital PCR to provide high sensitivity and accuracy in quantifying minimal residual disease -- those remaining cancer cells after therapy that are associated with relapse -- in blood diseases such as leukemia.

3 Dec 2018

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah (tisagenlecleucel, formerly CTL019) led to long-lasting remissions in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL).

3 Dec 2018

FDA approves new combination therapy for acute myeloid leukemia

Older patients with acute myeloid leukemia (AML) often aren't healthy enough to receive intensive chemotherapy, and gentler treatments aren't very effective in treating this aggressive blood cancer.

30 Nov 2018

Researchers reveal how some cancers trick healthy cells into protecting tumors

Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so aggressive that outcome is poor, even after early diagnosis and chemotherapy.

30 Nov 2018

Chemotherapy News and Research

Latest Chemotherapy News and Research

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

New technology for profiling genetic makeup of myeloma tumor cells developed

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

Lymph node ratio could predict survival in patients with oral cavity cancer

Breast cancer treatment more effective when determined by tumor cell count

Study: Chemotherapy agent did not improve survival in patients with triple-negative breast cancer

Researchers develop biosensors to detect and measure metastatic potential of cancer cells

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

International study increases group of lung cancer patients who may benefit from immunotherapy

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

New strategies may improve performance of CAR-T cell therapy in treating cancer

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

New drug combination could kill melanoma cells more effectively, study shows

UK scientists find new way to identify patients with aggressive lymphoma

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

FDA approves new combination therapy for acute myeloid leukemia

Researchers reveal how some cancers trick healthy cells into protecting tumors

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Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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