Chemotherapy News and Research

Latest Chemotherapy News and Research

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

A phase III clinical trial of 4,805 women with HER2-positive breast cancer suggests adding a second HER2 targeted medicine, pertuzumab (Perjeta), to standard of care trastuzumab (Herceptin) after surgery may help, although the benefit is modest.

6 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

Study: Cancer patients who used symptom-reporting Internet tool lived longer

Cancer patients who reported their symptoms to their cancer care providers using a web-based survey lived longer than those patients who did not, according to a study led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher.

5 Jun 2017

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

After surgery for lymph-node positive colon cancer (stage III), some patients may only need half of the long-standing standard course of chemotherapy.

5 Jun 2017

Testicular cancer survivors with low testosterone more likely to have chronic health problems

In a large study, 38% of 491 testicular cancer survivors had low testosterone levels, known as hypogonadism.

5 Jun 2017

Cannabinoids used in combination with chemotherapy found to be effective in killing leukemia cells

New research has confirmed that cannabinoids - the active chemicals in cannabis - are effective in killing leukemia cells, particularly when used in combination with chemotherapy treatments.

5 Jun 2017

Symptom self-reporting web-based tool could be used to help extend oncology patients' lives, study finds

The study funded by the Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) has found that a simple intervention such as a web-based tool that facilitates patients to report their symptoms in real time, triggering alerts to clinicians, can have major benefits such as longer survival.

5 Jun 2017

Electronic patient-reported symptom monitoring increases survival compared with usual cancer care

The integration of electronic patient-reported outcomes into the routine care of patients with metastatic cancer was associated with increased survival compared with usual care, according to a study published by JAMA.

5 Jun 2017

New targeted oral therapy results in durable responses across many kinds of cancer

Scientists may have developed the first targeted, oral, tumor-type agnostic therapy - a cancer medicine that works comparably well across many kinds of cancer, regardless of patient age. In clinical trials of adults and children with 17 different types of advanced cancer, larotrectinib treatment resulted in responses in 76% of patients.

5 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

A clinical trial of nearly 2,000 men shows that adding abiraterone acetate (Zytiga) to a standard initial treatment regimen for high-risk, advanced prostate cancer lowers the relative risk of death by 37%.

5 Jun 2017

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

A Yale Cancer Center clinical trial combining the immune checkpoint inhibitor (durvalumab/MEDI4736) with chemotherapy as preoperative treatment for early stage triple negative breast cancer disclosed a 71% pathologic complete response to the combination treatment in the initial phase I trial.

2 Jun 2017

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

The critical component of an experimental vaccine led to an escalating immune response in patients with sarcoma, an indicator of its potential anti-cancer effects.

2 Jun 2017

Yale researchers find racial and ethnic disparities in use of genetic test for breast cancer

A genetic test that helps doctors determine how best to treat breast cancer - and whether chemotherapy is likely to help- is significantly more likely to be administered to white women than blacks or Hispanics, a Yale study has found.

1 Jun 2017

Experimental drug increases progression-free survival in pancreatic cancer patients, clinical trial shows

By adding an experimental drug to a standard chemotherapy regimen, a subset of patients with metastatic pancreatic cancer had a significantly longer period before the cancer progressed as compared with those who received the standard treatment, according to a Phase 2 clinical trial led by an investigator at Fred Hutchinson Cancer Research Center.

1 Jun 2017

Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer

A novel vaccine therapy can generate immune responses in patients with head and neck squamous cell carcinoma (HNSCCa), according to researchers at the Abramson Cancer Center of the University of Pennsylvania.

31 May 2017

Combined modality treatment provides alternative to complete bladder removal for patients with MIBC

A meta-analysis of previously published cancer research showed no difference in five-year and 10-year survival rates between patients who underwent radical cystectomy, which is the surgical removal of the bladder, and a bladder-preserving combined modality treatment (CMT) plan, which combines radiation therapy, chemotherapy and the removal of the bladder tumor.

31 May 2017

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

New research suggests the bacteria that cause tuberculosis alter their metabolism to combat exposure to antimicrobials, and that these metabolic "escape pathways" might be neutralized by new drugs to shorten the troublesome duration of therapy.

31 May 2017

Researchers make significant advance in treatment of bowel cancer

New research led by Queen's University Belfast has discovered how a genomic approach to understanding bowel (colorectal) cancer could improve the prognosis and quality of life for patients.

31 May 2017

Many cancer patients' ED visits could be avoided with better symptom management, timely care

As many as 53 percent of cancer patients' Emergency Department visits that do not require admission could be avoided with better symptom management and greater availability of outpatient care tailored to their needs, according to a new study from Fred Hutchinson Cancer Research Center.

31 May 2017

Chemotherapy News and Research

Latest Chemotherapy News and Research

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Study: Cancer patients who used symptom-reporting Internet tool lived longer

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

Testicular cancer survivors with low testosterone more likely to have chronic health problems

Cannabinoids used in combination with chemotherapy found to be effective in killing leukemia cells

Symptom self-reporting web-based tool could be used to help extend oncology patients' lives, study finds

Electronic patient-reported symptom monitoring increases survival compared with usual cancer care

New targeted oral therapy results in durable responses across many kinds of cancer

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

Yale researchers find racial and ethnic disparities in use of genetic test for breast cancer

Experimental drug increases progression-free survival in pancreatic cancer patients, clinical trial shows

Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer

Combined modality treatment provides alternative to complete bladder removal for patients with MIBC

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

Researchers make significant advance in treatment of bowel cancer

Many cancer patients' ED visits could be avoided with better symptom management, timely care

Cancer Research - Second Edition eBook

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Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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