Chemotherapy News and Research

Latest Chemotherapy News and Research

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes - less than 2 percent of the total - but 70 percent of the genome is made into non-gene-encoding RNA.

29 Apr 2016

Experimental therapy has over 90% remission rate for advanced leukemia patients

Twenty-seven of 29 patients with an advanced type of leukemia that had proved resistant to multiple other forms of therapy went into remission after their T cells (disease-fighting immune cells) were genetically engineered to fight their cancers.

28 Apr 2016

Experimental cancer drug Nutlin-3 shows promise in cancelling effects of fragile X syndrome

A University of Wisconsin-Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome.

28 Apr 2016

IPC PAS‘s chemical sensor can rapidly and effectively detect fungal infections

Fungal infections are a serious problem in modern health care. A critical factor in their successful treatment is time: the faster they are detected, the more effectively dangerous infections can be prevented.

28 Apr 2016

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

The rise of antibiotic resistant bacterial pathogens is an increasingly global threat to public health. In the United States alone antibiotic resistant bacterial pathogens kill thousands every year.

27 Apr 2016

Series of routine tests may not be beneficial to patients with age-related disorder

A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do increase health care costs, pathologists report.

27 Apr 2016

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

Researchers have identified a rare genetic variation associated with a dramatically increased risk of severe acute pancreatitis in acute lymphoblastic leukemia (ALL) patients treated with the chemotherapy agent asparaginase. St. Jude Children's Research Hospital led the study, which appears today in the Journal of Clinical Oncology.

26 Apr 2016

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients.

26 Apr 2016

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

A new study produced by an interdisciplinary team led by Prof. Antonio Giordano, director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, tracks the development process and efficacy of the Italian translation of the Derriford Appearance Scale 24, an important clinical tool in identifying quality-of-life issues for breast cancer patients, especially concerns regarding body shame, depression, anxiety, overall appearance and appearance identity.

26 Apr 2016

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Photoswitchable agents might reduce side effects of a chemotherapy. So far, photodynamic therapies have been dependent on oxygen in the tissue. But hardly any oxygen exists in malignant, rapidly growing tumors.

25 Apr 2016

Targeted therapy for triple-negative breast cancer may prove beneficial

A targeted therapy for triple-negative breast cancer (TNBC), the most aggressive form of breast cancer, has shown potential promise in a recently published study. TNBC is the only type of breast cancer for which there are no currently approved targeted therapies.

22 Apr 2016

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

New research from Roswell Park Cancer Institute shows that promising cancer drugs used in combination can have significant therapeutic impact on a particularly aggressive subtype of diffuse large B-cell lymphoma (DH-DLBCL) in preclinical studies. The researchers will present their findings at the American Association for Cancer Research (AACR) Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Using a novel cell culture approach, Yale Cancer Center researchers have discovered critical vulnerabilities in adenoid cystic carcinoma (ACC), a rare and lethal glandular cancer with a high recurrence rate and few treatment options.

21 Apr 2016

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Researchers at Roswell Park Cancer Institute, in collaboration with investigators from the cooperative group SWOG, have found that use of multivitamins prior to diagnosis may reduce the risk of neuropathy in breast cancer patients treated with the class of drugs known as taxanes. The team will present their findings at the American Association for Cancer Research Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Most basal cell skin cancers are easily removed -- those on the arm, leg or back. But when the cancer is on the eyelid or when it starts to invade surrounding tissue, it's no longer straightforward.

21 Apr 2016

Experimental treatment shrinks rare pediatric tumor by 90%

When a baby's life was threatened by a rare pediatric cancer that would not respond to surgery or chemotherapy, doctors at Nemours Children's Hospital rapidly, successfully shrank the tumor by 90 percent using an experimental treatment, according to a new study published online in Pediatric Blood and Cancer.

20 Apr 2016

Genetic markers may influence how breast cancer patients respond to treatment

Two previously unrecognized genetic markers may predict whether breast cancer patients would benefit from chemotherapy followed by tamoxifen, according to preclinical research from Roswell Park Cancer Institute, in collaboration with the cooperative research group SWOG and St. Jude Children's Research Hospital. The results of this research will be presented at the American Association for Cancer Research Annual Meeting 2016, to be held April 16-20 in New Orleans.

20 Apr 2016

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

In a clinical trial of the immunotherapy drug pembrolizumab, half of 25 patients with a rare type of virus-linked skin cancer called Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long, on average, than with conventional chemotherapy.

20 Apr 2016

Nivolumab drug shows survival benefit in phase III trial of patients with head and neck cancer

The immunotherapy drug nivolumab has become the first to show a survival benefit in head and neck cancer, after a major international trial found that it was more effective than standard chemotherapy.

20 Apr 2016

Chemotherapy News and Research

Latest Chemotherapy News and Research

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

Experimental therapy has over 90% remission rate for advanced leukemia patients

Experimental cancer drug Nutlin-3 shows promise in cancelling effects of fragile X syndrome

IPC PAS‘s chemical sensor can rapidly and effectively detect fungal infections

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

Series of routine tests may not be beneficial to patients with age-related disorder

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Targeted therapy for triple-negative breast cancer may prove beneficial

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Experimental treatment shrinks rare pediatric tumor by 90%

Genetic markers may influence how breast cancer patients respond to treatment

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

Nivolumab drug shows survival benefit in phase III trial of patients with head and neck cancer

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Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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