Chemotherapy News and Research

Latest Chemotherapy News and Research

Sicor Biotech receives FDA approval for tbo-filgrastim to treat severe neutropenia

The U.S. Food and Drug Administration today approved Sicor Biotech's tbo-filgrastim to reduce the time certain patients receiving cancer chemotherapy experience severe neutropenia, a decrease in infection-fighting white blood cells called neutrophils.

30 Aug 2012

Study to investigate how breast cancer patients might benefit from exercise

Researchers in Edmonton and Calgary want to recruit 1,500 breast cancer patients over the next decade to find out how exercise and fitness affects cancer survival and recovery.

29 Aug 2012

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Esperance Pharmaceuticals today announced the completion of the run-in cohort of its Phase 2, randomized, multi‐center trial of EP‑100 in combination with paclitaxel for patients with advanced ovarian cancer. EP‐100 is a targeted membrane‐disrupting peptide (tMDP) designed to seek and destroy cancer cells that overexpress luteinizing hormone releasing hormone (LHRH) receptors on their surfaces.

29 Aug 2012

Herceptin® (trastuzumab) delivery methods: an interview with Dr Gustavo Ismael

Approximately 20% of all breast cancer patients have overexpression of HER2 (human epidermal growth factor receptor 2), resulting in a more aggressive phenotype, and a poor prognosis.

28 Aug 2012

Positive results from Spinifex’s EMA401 Phase 2 trial on postherpetic neuralgia

Spinifex Pharmaceuticals, an Australian pain drug development company, today announces positive headline results from the Phase 2 clinical trial of its lead product, EMA401, in postherpetic neuralgia (PHN), a painful condition that develops in some patients following herpes zoster (shingles) and where existing therapy does not relieve pain in all individuals.

28 Aug 2012

Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial

Morphotek, Inc. announced today that it has commenced a multi-center, Phase II study evaluating the safety and efficacy of MORAb-004 when combined with gemcitabine and docetaxel in the treatment of metastatic soft tissue sarcoma.

28 Aug 2012

America Stem Cell commences ASC-101 Phase I/II study in hematologic malignancies

America Stem Cell, Inc. announced today the initiation of a single-center study at The University of Texas MD Anderson Cancer Center evaluating ASC-101 in dual-umbilical cord transplantation in patients with hematologic malignancies.

28 Aug 2012

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Extra pounds-even within the overweight but not obese range-are linked to a higher risk of recurrence of the most common type of breast cancer despite optimal cancer treatment, according to a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

27 Aug 2012

Patients tend to have worse outcomes when GBM appears in more than one location

When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute.

27 Aug 2012

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Seattle Genetics, Inc. today announced the initiation of a phase Ib clinical trial evaluating SGN-75 in combination with everolimus (Afinitor) for patients with advanced metastatic renal cell carcinoma (RCC).

24 Aug 2012

Quantitative look at the whole experience of patients with pancreatic cancer

Every year, nearly 45,000 Americans are diagnosed with pancreatic cancer. The odds against those stricken by the disease are truly dismal; pancreatic cancer almost always kills within two years after diagnosis, no matter how it is treated. Even aggressive intervention with chemotherapy, radiation or surgery rarely yields more than an extra month to a year of survival, depending on the stage of the disease.

24 Aug 2012

ALDH enzyme marks melanoma stem cells

Cancer stem cells are defined by three abilities: differentiation, self-renewal and their ability to seed a tumor. These stem cells resist chemotherapy and many researchers posit their role in relapse. A University of Colorado Cancer Center study recently published in the journal Stem Cells, shows that melanoma cells with these abilities are marked by the enzyme ALDH, and imagines new therapies to target high-ALDH cells, potentially weeding the body of these most dangerous cancer creators.

24 Aug 2012

New method can differentiate between breast cancer patients with good and poor prognosis

It is now possible to identify aggressive breast cancers by interpreting the mathematical patterns in the cancer genome. Researchers at the University of Oslo, Norway (UiO) have developed a completely new method for differentiating between breast cancer patients with high and low risks of dying from the illness.

24 Aug 2012

NCKU research team identifies Au nanorod complex for cancer therapy

A National Cheng Kung University (NCKU) research team has discovered Near-Infrared Light-Responsive oligonucleotide-gated Au nanoensembles (Au nanorod complex), a potent new anti-cancer complex that is seen as a promising targeted therapy for curing cancer.

24 Aug 2012

Roundup: Ore. lawmakers examine 'disclosure' as way to limit malpractice claims; $2.8M in fraudulent public assistance given in Mass.; Md. exchange announcement Thursday

Lawmakers are expected to take up tort reform when the Oregon Legislature convenes next February. To get those discussions moving, a Patient Safety and Defensive Medicine Workgroup is developing draft legislation that includes issues such as confidentiality, mediation, dispute resolution, litigation, discovery and patient safety. Disclosure -- informing patients when a serious medical event has occurred in a hospital setting -- is also on the table.

24 Aug 2012

State roundup: Restraining order issued in Mo. health exchange fight

A judge issued a temporary restraining order Tuesday against Missouri's secretary of state, Robin Carnahan, to prevent her from finalizing the language of a ballot question on health insurance exchanges. Lt. Gov. Peter Kinder, a Republican, sought the restraining order while a state court considers whether the language of the ballot question is biased, a claim leveled by Kinder and the state's top Republicans.

23 Aug 2012

Article describes immune-related adverse events with newly approved melanoma drug

An internationally recognized melanoma researcher at Moffitt Cancer Center and colleagues at the University of Kiel in Germany, including Axel Hauschild, M.D. and Katharina C. K-hler, M.D., have published an article in the current issue of The Journal of Clinical Oncology that describes immune-related adverse events for patients receiving either tremelimumab or ipilimumab, the latter a drug approved last year by the U.S. Food and Drug Administration for treating metastatic melanoma and other cancers.

23 Aug 2012

Chemotherapy during pregnancy: an interview with Professor Sibylle Loibl

The incidence is about 1-3% of all breast cancers. The incidence seems to be increasing due to women delaying their childbearing to when they are in their thirties.

22 Aug 2012

Radiation therapy alone no longer the best choice for early follicular lymphoma

A University of Rochester Medical Center study published in the Journal of Clinical Oncology, challenges treatment guidelines for early stage follicular lymphoma, concluding that six different therapies can bring a remission, particularly if the patient is carefully examined and staged at diagnosis.

22 Aug 2012

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

VolitionRX Limited, a life sciences company focused on developing blood-based diagnostic tests, announces that its subsidiary Belgian Volition has signed an agreement with the Biobank of CHU UCL Mont-Godinne, an academic hospital in Yvoir, Belgium.

22 Aug 2012

Chemotherapy News and Research

Latest Chemotherapy News and Research

Sicor Biotech receives FDA approval for tbo-filgrastim to treat severe neutropenia

Study to investigate how breast cancer patients might benefit from exercise

Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer

Herceptin® (trastuzumab) delivery methods: an interview with Dr Gustavo Ismael

Positive results from Spinifex’s EMA401 Phase 2 trial on postherpetic neuralgia

Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial

America Stem Cell commences ASC-101 Phase I/II study in hematologic malignancies

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Patients tend to have worse outcomes when GBM appears in more than one location

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Quantitative look at the whole experience of patients with pancreatic cancer

ALDH enzyme marks melanoma stem cells

New method can differentiate between breast cancer patients with good and poor prognosis

NCKU research team identifies Au nanorod complex for cancer therapy

Roundup: Ore. lawmakers examine 'disclosure' as way to limit malpractice claims; $2.8M in fraudulent public assistance given in Mass.; Md. exchange announcement Thursday

State roundup: Restraining order issued in Mo. health exchange fight

Article describes immune-related adverse events with newly approved melanoma drug

Chemotherapy during pregnancy: an interview with Professor Sibylle Loibl

Radiation therapy alone no longer the best choice for early follicular lymphoma

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

Cancer Research - Second Edition eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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