Chemotherapy News and Research

Latest Chemotherapy News and Research

New mRNA vaccine strategy awakens immune system to fight cancer

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

18 Jul 2025

Researchers unveil drug complex that makes cancer cells self-report to immune system

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell.

18 Jul 2025

Study casts doubt on a widely used shortcut in rectal cancer drug trials

A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.

17 Jul 2025

New reviews highlight urgent need for GI cancer screening in younger adults

Early-onset gastrointestinal (GI) cancers are rising at alarming rates worldwide and, in the U.S., are increasing faster than any other type of early-onset cancer, including breast cancer, according to two recent literature reviews from Dana-Farber Cancer Institute.

17 Jul 2025

Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist.

16 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

WEE1 identified as a key driver of immune resistance in cancer

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues.

15 Jul 2025

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to lung adenocarcinoma cells, dramatically suppressing tumor growth in preclinical models. This approach not only inhibited cancer cell migration and invasion but also showed strong potential for safer, more precise lung cancer therapy.

14 Jul 2025

New immunotherapy targets leukemia at its root

Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.

14 Jul 2025

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC.

12 Jul 2025

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how ALKBH3-regulated m1A of ALDOA potentiates glycolysis and doxorubicin resistance of triple negative breast cancer cells.

12 Jul 2025

Intestinal microbiome and metabolite profiles linked to chemotherapy response in breast cancer

Announcing a new article publication for BIO Integration journal. Imbalances in the intestinal microbiome are closely associated with the occurrence and development of cancer, and can affect tumorigenesis by influencing the inflammatory response, regulating the immune system, producing specific metabolites, and participating in tumor signaling pathways.

11 Jul 2025

Hydrogels could be key to safer, smarter cancer drug delivery

Hydrogels could revolutionize cancer treatment by facilitating targeted drug delivery, reducing adverse effects, and enhancing therapeutic effectiveness.

11 Jul 2025

New chemotherapy regimen improves fertility outcomes in young Hodgkin's lymphoma patients

Young patients with advanced Hodgkin's lymphoma, a cancer of the lymphatic system, now have a better chance of having their own children after treatment.

10 Jul 2025

How hydrogels are shaping the future of targeted cancer drug delivery

A large-scale bibliometric analysis maps global research on hydrogels as next-generation drug delivery systems for cancer therapy. The study highlights emerging trends, key contributors, and future directions to advance precision medicine in oncology.

10 Jul 2025

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer

A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms."

10 Jul 2025

Combination therapy sets new survival standard for advanced biliary tract cancer

In a follow-up analysis to the pivotal TOPAZ-1 study, which established the combination therapy of durvalumab (an immunotherapy drug) plus gemcitabine and cisplatin (GemCis, chemotherapy drugs) as the first-line treatment for people with advanced biliary tract cancer (aBTC), researchers have shown that after three years more than twice as many study participants treated with durvalumab plus GemCis had survived compared to those treated with a placebo plus GemCis.

10 Jul 2025

Chemotherapy News and Research

Latest Chemotherapy News and Research

New mRNA vaccine strategy awakens immune system to fight cancer

Researchers unveil drug complex that makes cancer cells self-report to immune system

Study casts doubt on a widely used shortcut in rectal cancer drug trials

New reviews highlight urgent need for GI cancer screening in younger adults

Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

WEE1 identified as a key driver of immune resistance in cancer

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

New immunotherapy targets leukemia at its root

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

Intestinal microbiome and metabolite profiles linked to chemotherapy response in breast cancer

Hydrogels could be key to safer, smarter cancer drug delivery

New chemotherapy regimen improves fertility outcomes in young Hodgkin's lymphoma patients

How hydrogels are shaping the future of targeted cancer drug delivery

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer

Combination therapy sets new survival standard for advanced biliary tract cancer

Study identifies why some prostate cancers fail to respond to treatment

New combination therapy inhibits tumor growth and blocks drug-induced resistance in ovarian cancer

Multifunctional nanodisk enables cancer diagnosis, treatment and immune activation

Cancer Research - Second Edition eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research - Second Edition eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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