Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

FDA accepts for review Bristol-Myers Squibb's ORENCIA sBLA for severe RA

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration (FDA) has accepted for review a supplemental Biologics License Application (sBLA) for the subcutaneous formulation of ORENCIA® (abatacept), a treatment for adult patients with moderate to severe rheumatoid arthritis (RA) administered through an injection into the skin. Bristol-Myers Squibb submitted the sBLA to the FDA for the subcutaneous formulation of ORENCIA and received confirmation of its receipt on October 4, 2010.

7 Dec 2010

No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Investigators report no evidence of toxicity in the four hemophilia B patients enrolled to date in a gene therapy trial using a vector under development at St. Jude Children's Research Hospital and UCL (University College London) to correct the inherited bleeding disorder.

7 Dec 2010

Experimental flu vaccine triggers immune response, protects against flu

Vaccine production hinges on the availability of hundreds of millions of eggs - and even with the vaccine, flu still claims somewhere around 36,000 lives in the United States during a typical year.

7 Dec 2010

Screening for CCDC40 gene mutations may help determine risk for congenital heart defects

A gene that can cause congenital heart defects has been identified by a team of scientists, including a group from Princeton University. The discovery could lead to new treatments for those affected by the conditions brought on by the birth defect.

7 Dec 2010

Fraunhofer USA CMB receives FDA approval to initiate Phase I clinical trial of H5N1 influenza vaccine

Fraunhofer USA Center for Molecular Biotechnology announced today it has received approval from the Food and Drug Administration to proceed with the first human clinical trial of plant-produced H5N1 influenza vaccine.

6 Dec 2010

Amgen announces final study results of Nplate in adults with chronic ITP

Amgen Inc. today announced the final results from a 5-year open-label extension study investigating the long-term efficacy and safety of Nplate (romiplostim) in adult chronic immune (idiopathic) thrombocytopenic purpura. Chronic ITP is a serious autoimmune disorder characterized by low platelet counts in the blood (thrombocytopenia), which can lead to serious bleeding events.

6 Dec 2010

BioCryst reports Phase 2 trial data of forodesine in patients with CLL

BioCryst Pharmaceuticals, Inc. announced the presentation of new data that confirms forodesine's clinical activity in the treatment of chronic lymphocytic leukemia at the 52nd Annual American Society of Hematology Meeting & Exposition being held in Orlando, Florida.

6 Dec 2010

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell anemia, according to a preliminary analysis of a multicenter trial that includes St. Jude Children's Research Hospital.

6 Dec 2010

Study: REVLIMID and dexamethasone for high-risk smoldering multiple myeloma reduce risk of disease progression

Celgene International Sàrl (NASDAQ: CELG) announced that data evaluating combination therapy REVLIMID® (lenalidomide) and dexamethasone in patients with high-risk asymptomatic smoldering multiple myeloma were presented during the American Society of Hematology's annual meeting. The study reported REVLIMID and dexamethasone prolonged time to progression.

6 Dec 2010

Patients with H1N1 flu die due to over-reactive immune response: Research

On November 19, Jason Martin returned to the Medical Intensive Care Unit at Vanderbilt University Medical Center for the first time since he nearly died there during last year's H1N1 flu pandemic. The tall and burly Warren County, TN, ambulance worker - a 30-year-old, father of three young children - broke down and hugged some of the nurses he recognized.

6 Dec 2010

Lundbeck reports positive phase III study data of clobazam in treating seizures associated with LGS

Today, Lundbeck Inc. presented positive data from its pivotal phase III study to determine the efficacy and safety profiles of the investigational compound clobazam as adjunctive therapy in treating seizures associated with Lennox-Gastaut syndrome.

6 Dec 2010

Investigational study data of REVLIMID with rituximab or rituximab-containing regimen in CLL patients presented at ASH

Celgene International Sàrl announced that clinical data from two investigational studies evaluating the use of REVLIMID (lenalidomide) either with rituximab or following a rituximab-containing regimen in patients with chronic lymphocytic leukaemia were presented at the 52nd American Society of Hematology annual meeting.

6 Dec 2010

Seasonal light cycles can affect development of babies' specific brain function: Study

The season in which babies are born can have a dramatic and persistent effect on how their biological clocks function.

6 Dec 2010

Wide-scale study of flu vaccine's effectiveness in European children needed

A wide-scale study of the effectiveness of flu vaccine in children is needed in Europe to fully assess the benefits, not only in keeping the kids from getting sick, but limiting the spread of flu to adults.

4 Dec 2010

HHS, CCSC establish new national awards program

The US Department of Health and Human Services and the Critical Care Societies Collaborative have established a new national awards program. The National Awards Program to Recognize Achievements in Eliminating Healthcare-Associated Infections will annually recognize teams of critical care professionals and healthcare institutions that achieve excellence and notable, sustained improvements in preventing healthcare-associated infections, specifically infections in critical care.

4 Dec 2010

IDRI awarded $1.8M contract to develop adjuvant formulations for pandemic influenza

The Infectious Disease Research Institute has been awarded an $1.8 million contract from the Biomedical Advance Research and Development Authority. IDRI's work will focus on development of adjuvant formulations with options up to $8.5 million over three years when further development and manufacture of priority candidates are approved by the agency.

4 Dec 2010

NFID supports CDC's National Influenza Vaccination Week

The National Foundation for Infectious Diseases supports the Centers for Disease Control and Prevention's annual observance of National Influenza Vaccination Week to communicate the importance and availability of influenza vaccination into the winter months and beyond. It is critical that physicians and patients, especially parents of pediatric patients, remain vigilant about flu protection this and every year.

4 Dec 2010

Information technology could improve prevention, treatment of depression

Could information technology and data mining techniques be used to improve the diagnosis and treatment of depression? That's the question scientists in Australia hope to have answered in a forthcoming issue of the International Journal of Functional Informatics and Personalised Medicine.

4 Dec 2010

IDRI receives $790,200 BARDA grant to develop pandemic flu vaccine

The Infectious Disease Research Institute (IDRI) today announced it has received a $790,200 grant from the Biomedical Advanced Research and Development Authority (BARDA), part of the US Department of Health and Human Services. The grant enables technology transfer between IDRI and the Cantacuzino National Institute of Research and Development for Microbiology and Immunology (Bucharest, Romania), with the goal of producing a pandemic flu vaccine.

4 Dec 2010

Zometa improves OS, PFS in newly diagnosed multiple myeloma patients: Phase III study

A newly published study in the Lancet suggested that a first-line treatment regimen including Zometa (zoledronic acid) significantly improved overall survival and progression-free survival in newly diagnosed multiple myeloma patients compared with a regimen that included oral clodronate. The impact on survival was independent of the effect of Zometa on bone complications (also known as skeletal-related events or SREs).

4 Dec 2010

Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

FDA accepts for review Bristol-Myers Squibb's ORENCIA sBLA for severe RA

No evidence of toxicity in hemophilia B patients enrolled in gene therapy trial

Experimental flu vaccine triggers immune response, protects against flu

Screening for CCDC40 gene mutations may help determine risk for congenital heart defects

Fraunhofer USA CMB receives FDA approval to initiate Phase I clinical trial of H5N1 influenza vaccine

Amgen announces final study results of Nplate in adults with chronic ITP

BioCryst reports Phase 2 trial data of forodesine in patients with CLL

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

Study: REVLIMID and dexamethasone for high-risk smoldering multiple myeloma reduce risk of disease progression

Patients with H1N1 flu die due to over-reactive immune response: Research

Lundbeck reports positive phase III study data of clobazam in treating seizures associated with LGS

Investigational study data of REVLIMID with rituximab or rituximab-containing regimen in CLL patients presented at ASH

Seasonal light cycles can affect development of babies' specific brain function: Study

Wide-scale study of flu vaccine's effectiveness in European children needed

HHS, CCSC establish new national awards program

IDRI awarded $1.8M contract to develop adjuvant formulations for pandemic influenza

NFID supports CDC's National Influenza Vaccination Week

Information technology could improve prevention, treatment of depression

IDRI receives $790,200 BARDA grant to develop pandemic flu vaccine

Zometa improves OS, PFS in newly diagnosed multiple myeloma patients: Phase III study

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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