Constipation News and Research

Latest Constipation News and Research

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

The U.S. Food and Drug Administration today approved Kisqali (ribociclib) in combination with an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy.

19 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Genetically engineered bacteria shows promise as new treatment for constipation

Genetically engineered bacteria are showing promise as a new treatment for constipation, researchers at the Mayo Clinic Center for Individualized Medicine have discovered in a mouse study.

14 Jun 2018

Mangos found to be more effective in reducing symptoms of constipation

Next time you suffer from constipation, you may want to consider grabbing a mango instead of reaching for a fiber supplement, suggests a new Texas A & M University pilot study published in the peer-reviewed journal Molecular Nutrition and Food Research.

6 Jun 2018

Cedars-Sinai study identifies gut gas associated with diarrhea

Cedars-Sinai investigators have for the first time identified a gas produced in gut that could improve the diagnosis and treatment of patients with two common intestinal illnesses-;small intestine bacterial overgrowth and irritable bowel syndrome.

6 Jun 2018

Acoustic technology could offer new way to diagnose IBS

Utilizing newly adapted artificial intelligence, researchers have developed an acoustic belt that offers a new way to diagnose irritable bowel syndrome by listening to the noises in a patient's gut, according to research presented at Digestive Disease Week 2018.

5 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

More suspected cancer cases can be identified early within primary care

Considerably more cases of suspected cancer can today be identified early within primary care. Partly based on symptoms but also statistics on the patients' visits to health centers, indicates research from Sahlgrenska Academy at University of Gothenburg, Sweden.

27 Apr 2018

New compound could offer pain-relieving properties without risk of addiction

Researchers at the University of Michigan have engineered a new compound that animal tests suggest could offer the pain-relieving properties of opioids such as morphine and oxycodone without the risk of addiction.

24 Apr 2018

Home-based treatment program offers robust and sustained relief for IBS patients

In the largest federally funded non-drug clinical trial for irritable bowel syndrome, patients with the most severe and persistent symptoms achieved robust and sustained relief by learning to control symptoms with minimal clinician contact. Led by University at Buffalo researchers in collaboration with colleagues at New York University and Northwestern University, the study was published online before print in Gastroenterology.

23 Apr 2018

Hacking 'drug trafficking' system could increase effectiveness of diabetes treatment

Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective.

23 Apr 2018

People with vitamin D deficiency may be at greater risk of diabetes

An epidemiological study conducted by researchers at University of California San Diego School of Medicine and Seoul National University suggests that persons deficient in vitamin D may be at much greater risk of developing diabetes.

20 Apr 2018

NSAIDs alone or with acetaminophen better than opioids at easing dental pain

Opioids are not among the most effective-or longest lasting- options available for relief from acute dental pain, a new examination of the results from more than 460 published studies has found.

17 Apr 2018

Prostate cancer on the rise and detected late in the UK finds report

As many as 37 percent of all prostate cancers are detected late or in advanced stages in the UK, finds a new report from the charity Orchid. The report suggests that most of these cancers are detected at stages 3 and 4. Statistics show that nearly 47,000 men are diagnosed with prostate cancer annually and 11,000 succumb to the disease each year.

9 Apr 2018

Constipation News and Research

Latest Constipation News and Research

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Genetically engineered bacteria shows promise as new treatment for constipation

Mangos found to be more effective in reducing symptoms of constipation

Cedars-Sinai study identifies gut gas associated with diarrhea

Acoustic technology could offer new way to diagnose IBS

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Celgene to share new and updated data around novel hematological therapies

More suspected cancer cases can be identified early within primary care

New compound could offer pain-relieving properties without risk of addiction

Home-based treatment program offers robust and sustained relief for IBS patients

Hacking 'drug trafficking' system could increase effectiveness of diabetes treatment

People with vitamin D deficiency may be at greater risk of diabetes

NSAIDs alone or with acetaminophen better than opioids at easing dental pain

Prostate cancer on the rise and detected late in the UK finds report

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Constipation News and Research

Latest Constipation News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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