Constipation

Constipation is a condition in which stool becomes hard, dry, and difficult to pass, and bowel movements don’t happen very often. Other symptoms may include painful bowel movements, and feeling bloated, uncomfortable, and sluggish.

What is Constipation?

Constipation is a condition characterized by inability to pass stools that become hard and more difficult to pass.

Constipation Treatments

Causes of Constipation

Constipation in the Elderly

Constipation in Babies

Constipation Symptoms

Constipation Diagnosis

Constipation in Children

Slow Transit Constipation

Constipation Prevention

Drugs that Cause Constipation

Latest Constipation News and Research

New global guidelines aim to make clozapine safer and more accessible

The most effective antipsychotic drug for people with treatment-resistant schizophrenia is clozapine.

3 Jul 2025

Study finds significant uptick in chronic digestive disorders during COVID-19 pandemic

A study led by Cedars-Sinai investigators uncovered a significant uptick in chronic digestive disorders, like irritable bowel syndrome, during the COVID-19 pandemic.

3 Jul 2025

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2 Jul 2025

Once-monthly obesity injection shows double-digit weight loss in major clinical trial

Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials.

24 Jun 2025

Cagrilintide and semaglutide together drive record weight loss in global trial

A 68-week phase 3 trial found that coadministered cagrilintide and semaglutide led to significant and clinically meaningful weight loss in adults with obesity but no diabetes. The combination outperformed either drug alone and improved multiple cardiometabolic health markers.

23 Jun 2025

Diabetes medication shows promise in cutting migraine days by more than half

A diabetes medication that lowers brain fluid pressure has cut monthly migraine days by more than half, according to a new study presented today at the European Academy of Neurology (EAN) Congress 2025.

20 Jun 2025

Gut microbiome resists major changes from a nut-rich diet

The systematic review highlights that while nuts influence gut microbiota, the effects are modest and vary by nut type, warranting further investigation.

18 Jun 2025

Chromium-rich fiber supplement keeps you fuller and reduces insulin spikes

A single dose of a chromium-enriched glucomannan-fructo-oligosaccharide fiber complex significantly reduced postprandial insulin and increased fullness in healthy adults, without affecting blood glucose. These findings highlight the potential of this functional fiber blend to support appetite control and metabolic health.

10 Jun 2025

Weekly risperidone capsule delivers consistent drug levels for schizophrenia patients

For many patients with schizophrenia, other psychiatric illnesses, or diseases such as hypertension and asthma, it can be difficult to take their medicine every day.

10 Jun 2025

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

Ghrelin receptor identified as key to easing constipation in Parkinson’s patients

Considered the natural "hunger hormone", Ghrelin could be the key to preventing debilitating chronic constipation experienced by people living with Parkinson's disease, University of Queensland researchers have found.

28 May 2025

UArizona researchers uncover new way to ease postoperative pain in women

University of Arizona Health Sciences researchers identified a potential way to reduce female post-operative pain by inhibiting pituitary prolactin generated by pre-operative stress.

20 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Experimental drug could offer pain relief without the side effects of opioids

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids.

19 May 2025

Study finds fewer H. pylori infections among Parkinson’s patients

A large case-control study from China found that people with Parkinson’s disease were significantly less likely to test positive for Helicobacter pylori infection compared to controls. The findings suggest a potential protective link between this common stomach bacterium and Parkinson’s disease, though causality remains unproven.

15 May 2025

Can diet ease IBS? A low-FODMAP plan cut symptoms but raised nutrient concerns

A 10-week low-FODMAP diet significantly reduced symptom severity in Saudi adults with IBS, with most shifting from severe to moderate symptoms. However, the restrictive diet also led to declines in several essential nutrients, highlighting the need for professional guidance.

14 May 2025

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

High intake of ultra processed foods linked to early signs of Parkinson's

People who eat more ultra processed foods like cold breakfast cereal, cookies and hot dogs are more likely to have early signs of Parkinson's disease when compared to those who eat very few ultra processed foods, according to a study published in the May 7, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

7 May 2025

Ten-year data confirm exercise is a powerful tool against depression

Researchers review how exercise influences depression in otherwise healthy adults.

7 May 2025

Varicose veins increase your risk of dementia, study finds

A nationwide Korean study finds a surprising link between varicose veins and dementia, and suggests that treating the veins could help prevent vascular brain damage.

6 May 2025