Constipation

Constipation is a condition in which stool becomes hard, dry, and difficult to pass, and bowel movements don’t happen very often. Other symptoms may include painful bowel movements, and feeling bloated, uncomfortable, and sluggish.

What is Constipation?

Constipation is a condition characterized by inability to pass stools that become hard and more difficult to pass.

Drugs that Cause Constipation

Constipation Diagnosis

Constipation Treatments

Constipation in Children

Constipation Prevention

Slow Transit Constipation

Constipation in Babies

Causes of Constipation

Constipation Symptoms

Constipation in the Elderly

Latest Constipation News and Research

Late-night eating may amplify the effects of stress on gut health

It's well known that chronic stress can disrupt bowel function, sending people running to the bathroom or making them constipated.

23 Apr 2026

Gut microbiome clues may help spot Parkinson’s disease in its earliest phase

Researchers found that a Parkinson’s disease-related gut microbiome pattern appears not only in people with diagnosed Parkinson’s, but also in some non-manifesting GBA1 variant carriers and a subset of healthy individuals. The findings suggest that gut microbiome changes may help flag people who are closer to Parkinson’s disease development, although longitudinal studies are still needed to confirm predictive value.

21 Apr 2026

Higher mortality risk in IBS patients using antidepressants

Research indicates that antidepressant use in IBS is linked to a 35% higher risk of all-cause mortality, highlighting safety issues with long-term treatment.

13 Apr 2026

IBS diagnosis gaps persist across racial and gender groups in the U.S.

A national survey study led by UCLA Health and Cedars-Sinai Medical Center found significant disparities in how irritable bowel syndrome, or IBS, is diagnosed across sex and racial groups in the U.S., with men and Black patients considerably less likely than women and white patients to receive a formal diagnosis.

9 Apr 2026

Inside the high-stakes corporate fight over feeding preterm babies

In 2013, a scientist at Abbott Laboratories saw study results with potentially big implications for the company's profits and the lives of some of the world's most fragile people: preterm infants.

30 Mar 2026

Childhood stress may lead to digestive issues later in life

Early life stress may lead to digestive issues later in life, driven by changes in the gut and sympathetic nervous systems, according to a new study published in the journal Gastroenterology.

16 Mar 2026

Researchers propose that Parkinson’s disease may start in the gut, not the brain

A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.

5 Mar 2026

Study reveals bacterial duo driving chronic constipation

Scientists at Nagoya University in Japan have found two gut bacteria working together that contribute to chronic constipation.

19 Feb 2026

How GLP-1 drugs affect the body beyond weight loss and glucose control

This review evaluates the safety profile of glucagon-like peptide-1 receptor agonists and related incretin therapies used for obesity and type 2 diabetes. It highlights common gastrointestinal effects, rare but debated risks, and areas where further long-term safety data are still needed.

18 Feb 2026

Ozempic users continue treatment when weight loss works despite side effects

A study on Ozempic for weight loss reveals user satisfaction is driven by efficacy, despite common gastrointestinal side effects impacting treatment adherence.

13 Feb 2026

Blood gene signals reveal Parkinson’s risk years before diagnosis

Blood-based DNA repair and stress-response signals reveal early molecular changes in Parkinson's disease, aiding in potential early diagnosis and intervention.

2 Feb 2026

Two-thirds of adolescent IBS sufferers outgrow the condition by adulthood

Two out of three adolescents with irritable bowel syndrome (IBS) start adulthood without the disease, according to a long-term study that followed more than 2,500 individuals.

2 Feb 2026

Biomarker discovery may pave the way for early diagnosis of Parkinson's

A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson's disease in its earliest stages, before extensive brain damage has occurred.

29 Jan 2026

New evidence shows Parkinson’s spreads via immune cells from the gut

New research reveals how Parkinson's spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK Dementia Research Institute at UCL (University College London).

29 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

Genetic study links vitamin B1 metabolism to gut motility and IBS risk

Research links thiamine metabolism to gut motility, identifying genetic markers that could lead to new therapies for IBS and related digestive disorders.

23 Jan 2026

New genetic insights reveal vitamin B1's role in gut health and motility

Bowel habits aren't exactly dinner-table talk. But they reflect how quickly the gut moves things along, and when that goes wrong people can experience constipation, diarrhoea, or irritable bowel syndrome (IBS).

20 Jan 2026

Dietary intervention eases celiac symptoms in children but not quality of life

The Gluten3S research group launched a dietary intervention with children who had recently been diagnosed with celiac disease.

14 Jan 2026

Scientists identify a molecular switch that controls water flow in the gut

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

9 Jan 2026

$AGA's new update urges caution before surgical treatment of refractory constipation$

AGA's new update urges caution before surgical treatment of refractory constipation

A new update from the American Gastroenterological Association (AGA) is calling for greater caution before surgery is considered for patients with refractory constipation, a severe, chronic form of constipation that does not respond to standard treatments.

7 Jan 2026