Constipation News and Research

Latest Constipation News and Research

Researchers reveal biological connection between obesity and colorectal cancer risk

Obesity has long been associated with increased risk of colorectal cancer, but the link has never been understood. Now, a research team led by investigators at Thomas Jefferson University has revealed the biological connection, and in the process, has identified an approved drug that might prevent development of the cancer.

18 Jan 2016

U.S. Marshals seize nearly 90,000 bottles of dietary supplements containing kratom

The U.S. Food and Drug Administration announced today that U.S. Marshals, at the agency's request, seized nearly 90,000 bottles of dietary supplements labeled as containing kratom. The product, manufactured for and held by Dordoniz Natural Products LLC, located in South Beloit, Illinois, is marketed under the brand name RelaKzpro and worth more than $400,000.

7 Jan 2016

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on gastrointestinal and cardio-renal diseases, today announced positive results of an open label clinical study evaluating the pharmacodynamic (PD) activity of RDX022 in healthy adult volunteers.

5 Jan 2016

FDA issues two final orders to strengthen requirements for transvaginal surgical mesh safety

The U.S. Food and Drug Administration today issued two final orders to manufacturers and the public to strengthen the data requirements for surgical mesh to repair pelvic organ prolapse (POP) transvaginally, or through the vagina.

5 Jan 2016

New oral breast cancer drug has potential to combat other types of cancer

Palbociclib, a new oral drug whose efficacy in combating breast cancer has been demonstrated alone and in combination with endocrine therapy, also has potential to combat other types of cancer, according to a literature review and additional original research conducted by experts at the Abramson Cancer Center in the University of Pennsylvania published this month in JAMA Oncology.

30 Dec 2015

Study looks at long-term effects of psychological therapies in patients with irritable bowel syndrome

For some time doctors have known that psychological therapies can reduce the symptoms of irritable bowel syndrome in the short term.

29 Dec 2015

Vitamin D plays substantial role in patient outcomes after weight-loss surgery

Low levels of vitamin D have long been identified as an unwanted hallmark of weight loss surgery, but now findings of a new Johns Hopkins study of more than 930,000 patient records add to evidence that seasonal sun exposure -- a key factor in the body's natural ability to make the "sunshine vitamin" -- plays a substantial role in how well people do after such operations.

23 Dec 2015

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced (metastatic) ALK-positive non-small cell lung cancer (NSCLC) whose disease has worsened after, or who could not tolerate treatment with, another therapy called Xalkori (crizotinib).

11 Dec 2015

Lilly, Merck announce another immuno-oncology collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced another immuno-oncology collaboration that will evaluate abemaciclib (LY2835219), Lilly's cyclin-dependent kinase (CDK) 4 and 6 inhibitor, and Merck's KEYTRUDA (pembrolizumab) in a Phase I study across multiple tumor types.

10 Dec 2015

Cognitive behavioral therapy can be equally effective as second generation antidepressant for depression

Major depressive disorder affects more than 32 million Americans, and their first stop for treatment is often their primary care provider. A recent evidence review of several alternatives to medication found that using cognitive behavioral therapy as the first treatment for depression can be equally effective as using a second generation antidepressant.

10 Dec 2015

Kanuma approved as first treatment for patients with LAL deficiency

Today, the U.S. Food and Drug Administration approved Kanuma (sebelipase alfa) as the first treatment for patients with a rare disease known as lysosomal acid lipase (LAL) deficiency.

8 Dec 2015

Takeda presents Phase 3 TOURMALINE-MM1 data for multiple myeloma at ASH 2015

Takeda Pharmaceutical Company Limited today announced results from the TOURMALINE-MM1 trial presented at the 57th Annual Meeting and Exposition of the American Society of Hematology (ASH), showing that treatment with NINLARO (ixazomib) capsules is effective in extending progression free survival (PFS) with a manageable tolerability profile in patients with relapsed and/or refractory multiple myeloma.

8 Dec 2015

Synthetic Biologics announces positive results from first SYN-004 Phase 2a study for prevention of CDI, AAD

Synthetic Biologics, Inc.), a clinical stage company focused on developing therapeutics to protect the gut microbiome while targeting pathogen specific diseases, announced positive topline results from the first Phase 2a study of SYN-004, the Company's candidate designed to protect the gut microbiome from the unintended effects of certain commonly used intravenous (IV) beta-lactam antibiotics for the prevention C. difficile infection (CDI) and antibiotic-associated diarrhea (AAD).

1 Dec 2015

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Empliciti (elotuzumab) in combination with two other therapies to treat people with multiple myeloma who have received one to three prior medications.

30 Nov 2015

Specific HRQOL components need to be targeted for achieving optimal care for older cancer patients

In a paper recently published in the European Journal of Cancer, EORTC researchers identified health related quality of life (HRQOL) components that should be considered as most relevant for achieving optimal care for older cancer patients.

26 Nov 2015

Slower aging reduces degeneration related to Parkinson's disease

Humans have long sought to reduce the effects of aging. Now, there may be another reason to continue searching for ways to slow the clock--preventing Parkinson's disease.

25 Nov 2015

Opdivo (nivolumab) approved to treat patients with advanced renal cell carcinoma

The U.S. Food and Drug Administration today approved Opdivo (nivolumab) to treat patients with advanced (metastatic) renal cell carcinoma, a form of kidney cancer, who have received a certain type of prior therapy.

23 Nov 2015

AfBPM's second National Summit aims to improve pain management, patient safety

The Alliance for Balanced Pain Management, a diverse collective of 24 health care advocacy groups, patient organizations, industry representatives and other stakeholders, held its second National Summit on Nov. 12 and 13, 2015, to identify continued ways to support appropriate access to integrated pain management and responsible use of prescription pain medicines with an aim to improve patient safety and reduce abuse.

21 Nov 2015

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Ninlaro (ixazomib) in combination with two other therapies to treat people with multiple myeloma who have received at least one prior therapy.

21 Nov 2015

Medical researchers use social media to study harmful side effects of narcotics medication

Harnessing the power of social media, medical researchers have sifted through more than two billion tweets and online posts to study the harmful side effects of narcotics medication taken for chronic pain.

19 Nov 2015

Constipation News and Research

Latest Constipation News and Research

Researchers reveal biological connection between obesity and colorectal cancer risk

U.S. Marshals seize nearly 90,000 bottles of dietary supplements containing kratom

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

FDA issues two final orders to strengthen requirements for transvaginal surgical mesh safety

New oral breast cancer drug has potential to combat other types of cancer

Study looks at long-term effects of psychological therapies in patients with irritable bowel syndrome

Vitamin D plays substantial role in patient outcomes after weight-loss surgery

Alecensa (alectinib) approved for treatment of people with advanced ALK-positive NSCLC

Lilly, Merck announce another immuno-oncology collaboration

Cognitive behavioral therapy can be equally effective as second generation antidepressant for depression

Kanuma approved as first treatment for patients with LAL deficiency

Takeda presents Phase 3 TOURMALINE-MM1 data for multiple myeloma at ASH 2015

Synthetic Biologics announces positive results from first SYN-004 Phase 2a study for prevention of CDI, AAD

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Specific HRQOL components need to be targeted for achieving optimal care for older cancer patients

Slower aging reduces degeneration related to Parkinson's disease

Opdivo (nivolumab) approved to treat patients with advanced renal cell carcinoma

AfBPM's second National Summit aims to improve pain management, patient safety

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Medical researchers use social media to study harmful side effects of narcotics medication

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Constipation News and Research

Latest Constipation News and Research

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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