Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Discovery of 100 new genes may aid research into pigmentation diseases

A new study identified more than 100 genes that play a key role in determining the color of human hair. The findings may have important implications for pigmentation diseases such as melanoma.

17 Apr 2018

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Although the vast majority of research on the gut microbiome has focused on bacteria in the large intestine, a new study - one of a few to concentrate on microbes in the upper gastrointestinal tract - shows how the typical calorie-dense western diet can induce expansion of microbes that promote the digestion and absorption of high-fat foods.

11 Apr 2018

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis.

5 Apr 2018

Anti-TNF medications appear to be safe for use during pregnancy, study shows

Anti-tumor necrosis factor medications are effective in controlling chronic inflammatory diseases, but some physicians recommend that their patients discontinue them during pregnancy.

5 Apr 2018

New review explores potentially safer therapies for treating chronic abdominal pain

An estimated 2 million people in the U.S. are addicted to prescription opioids- powerful doctor-prescribed medications for chronic or severe pain. The drugs are commonly prescribed to treat gastrointestinal pain caused by conditions such as Crohn's disease and irritable bowel syndrome (IBS), raising the risk of addiction among this population.

29 Mar 2018

Macrophages stimulated to produce potent anti-inflammatory molecule

Researchers have discovered that macrophages, which play a key role in inflammation, also produce an anti-inflammatory molecule called itaconate.

29 Mar 2018

Artificial sweetener sucralose worsens gut inflammation in mice with Crohn's disease

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's-like disease, but had no substantive effect on those without the condition.

15 Mar 2018

University Hospitals study suggests strong connection between IBD and heart attacks

University Hospitals Harrington Heart & Vascular Institute researchers Muhammad Panhwar, MD, and Mahazarin Ginwalla, MD, recently concluded a study of more than 22 million patients that suggests a strong connection between Inflammatory Bowel Disease (IBD) and the development of heart disease and heart attacks.

6 Mar 2018

Inflammatory bowel disease linked to elevated risk of heart attack

An analysis of medical-record data from more than 17.5 million patients found that people with inflammatory bowel disease (IBD) are at elevated risk for a heart attack, regardless of whether or not they have traditional risk factors for heart disease such as high cholesterol, high blood pressure and smoking.

1 Mar 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Psoriasis drug also effective at reducing aortic inflammation

Ustekinumab, sold under the name Stelara, is approved by the U.S. Food and Drug Administration to treat psoriasis, psoriatic arthritis, and Crohn's Disease. Researchers wanted to know if the benefits of the drug go beyond clearing the skin.

18 Feb 2018

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

The human microbiome - the trillions of tiny bacteria that live in and on our bodies - is emerging as an increasingly important player in health and wellness. But, our co-existence with these organisms is complex, and scientists are learning that even minor changes in this relationship can lead to big problems with our health.

9 Feb 2018

Gene expression is rhythmic in most tissue types

Researchers have mapped primate gene expression throughout the day and discovered that the majority of critical gene activity is time dependent, which may aid the development of new treatments for many diseases.

9 Feb 2018

International research collaboration finds genetic mutation linked to Crohn's disease

A genetic mutation was found to be associated with Crohn's disease. The discovery was made by international research collaboration and was published in the prestigious journal Science Translational Medicine.

8 Feb 2018

Researchers discover link between rheumatoid arthritis and bacteria in milk

A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida.

30 Jan 2018

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by prof. Savvas Savvides has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease.

18 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Implanted robotic system stimulates tissue growth in stunted organs

An implanted, programmable medical robot can gradually lengthen tubular organs by applying traction forces -- stimulating tissue growth in stunted organs without interfering with organ function or causing apparent discomfort, report researchers at Boston Children's Hospital.

11 Jan 2018

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

UT Southwestern Medical Center researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.

5 Jan 2018

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Discovery of 100 new genes may aid research into pigmentation diseases

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Anti-TNF medications appear to be safe for use during pregnancy, study shows

New review explores potentially safer therapies for treating chronic abdominal pain

Macrophages stimulated to produce potent anti-inflammatory molecule

Artificial sweetener sucralose worsens gut inflammation in mice with Crohn's disease

University Hospitals study suggests strong connection between IBD and heart attacks

Inflammatory bowel disease linked to elevated risk of heart attack

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Psoriasis drug also effective at reducing aortic inflammation

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

Gene expression is rhythmic in most tissue types

International research collaboration finds genetic mutation linked to Crohn's disease

Researchers discover link between rheumatoid arthritis and bacteria in milk

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

New study shows how the immune system regulates gut fungal population

Implanted robotic system stimulates tissue growth in stunted organs

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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