Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Study opens new avenue for treating ulcerative colitis or Crohn's disease

An international study led by the Complutense University of Madrid (UCM) and the National Centre for Cardiovascular Research (CNIC) has found that Lactobacillus bacteria present in the intestinal microbiota interact with immune system cells to strengthen the intestinal barrier.

31 Jan 2019

Researchers uncover specific microbial signatures of intestinal disease

Researchers from the Department of Biomedical Research of the University of Bern and the University Clinic of Visceral Surgery and Medicine of the Inselspital Bern, Switzerland, have discovered that changes in the composition of the intestinal bacteria in patients with chronic inflammatory bowel disease affect the severity of the disease and the success of therapy.

21 Jan 2019

Women with IBD have increased risk of developing mental illness, finds study

A study published today in the journal Gut shows that women with inflammatory bowel disease are at greater risk of developing a mental illness after giving birth compared to the overall population.

10 Jan 2019

Microbial metabolite from pomegranates can reduce and protect against IBD

Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease.

10 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Malnutrition in children with Crohn's disease linked with increased risk of surgical complications

Results of a medical records study of children with Crohn's disease by Johns Hopkins researchers have added substantial evidence for a strong and direct link between malnutrition and increased risk of surgical complications and poor outcomes.

17 Dec 2018

Allen Institute for Immunology: A new division focused on human immune system

The Allen Institute today announced the launch of the Allen Institute for Immunology, a new division of the Institute that is dedicated to studying the human immune system.

13 Dec 2018

Men with inflammatory bowel disease have higher prostate cancer risk

Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer, reports a 20-year study from Northwestern Medicine.

7 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Scientists discover new inhibitor that decreases lung inflammation

Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome - a life-threatening disease which affects thousands of people in the UK.

18 Nov 2018

Inflammation can cause sleep and shiftwork-type disorders

Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new Northwestern Medicine study in mice found.

31 Oct 2018

New approach using 'cellular dust' offers hope for regenerative medicine

While stem cells have the most therapeutic potential, the benefits of regenerative medicine may best be mobilized using extracellular vesicles (EVs), also known in the past as "cellular dust".

24 Oct 2018

Cannabis oil shown to significantly improve Crohn’s disease symptoms

In the first study of its kind, cannabis oil has been shown to significantly improve the symptoms of Crohn’s disease and the quality of life of sufferers but, contrary to previous medical thinking, has no effect on gut inflammation.

23 Oct 2018

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

AbbVie, a research-based global biopharmaceutical company, today announced positive results from U-ACHIEVE, an ongoing Phase 2b/3 dose-ranging study evaluating upadacitinib, an investigational JAK1-selective inhibitor, for induction and maintenance therapy in adult patients with moderately to severely active ulcerative colitis.

23 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda Pharmaceutical Company Limited today announced results from the phase 3 VISIBLE 1 clinical trial evaluating the efficacy and safety of an investigational subcutaneous formulation of the gut-selective biologic vedolizumab for maintenance therapy in adult patients with moderately to severely active ulcerative colitis who achieved clinical response* at week 6 following two doses of open-label vedolizumab intravenous induction therapy.

22 Oct 2018

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

A bioelectronic medicine device was effective in reducing pain and fatigue in patients with lupus, according to Feinstein Institute for Medical Research Professor Cynthia Aranow, MD, who will present pilot clinical trial results Tuesday at the American College of Rheumatology/Association of Rheumatology Professional's Annual Meeting.

22 Oct 2018

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Gilead Sciences, Inc. and Galapagos NV today announced detailed results from the Phase 3 FINCH 2 clinical trial of filgotinib, an investigational, selective JAK1 inhibitor, in adults with moderately-to-severely active rheumatoid arthritis and prior inadequate response or intolerance to biologic agents.

22 Oct 2018

Study reports increased risk of death in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports.

19 Oct 2018

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Study opens new avenue for treating ulcerative colitis or Crohn's disease

Researchers uncover specific microbial signatures of intestinal disease

Women with IBD have increased risk of developing mental illness, finds study

Microbial metabolite from pomegranates can reduce and protect against IBD

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Gut microbiome plays role in immune system regulation, study finds

Malnutrition in children with Crohn's disease linked with increased risk of surgical complications

Allen Institute for Immunology: A new division focused on human immune system

Men with inflammatory bowel disease have higher prostate cancer risk

Customizing Genetically Engineered Models for Specific Research Applications

Scientists discover new inhibitor that decreases lung inflammation

Inflammation can cause sleep and shiftwork-type disorders

New approach using 'cellular dust' offers hope for regenerative medicine

Cannabis oil shown to significantly improve Crohn’s disease symptoms

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Study reports increased risk of death in children with inflammatory bowel disease

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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