Dentistry News and Research

Latest Dentistry News and Research

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Newly developed personalized vaccine system could delay onset of pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a personalized vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in individuals at high risk of developing this disease and to slow down tumor growth in patients who are affected by it.

26 Nov 2019

Using behavioral sciences to promote oral health

2019 marks the Centennial of the Journal of Dental Research. Over the last century the JDR has been dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry and to the oral cavity and associated structures in health and disease.

22 Nov 2019

Added sugar in 60 percent of infant, toddler foods

How young do you have to be to escape the lure of unhealthy foods? It’s never too young, finds a new study published in the Journal of the Academy of Nutrition and Dietetics on November 14, 2019.

14 Nov 2019

Study looks at trends in added sugars consumption by infants and toddlers

A new study in the Journal of the Academy of Nutrition and Dietetics, published by Elsevier, found that nearly two-thirds of infants (61 percent) and almost all toddlers (98 percent) consumed added sugars in their average daily diets, primarily in the form of flavored yogurts (infants) and fruit drinks (toddlers). Infants were 6-11 months, and toddlers were 12-23 months.

14 Nov 2019

Frail patients more likely to die even after low-stress surgical procedures

The threshold for when to perform elective surgery in a frail patient may be much higher than previously thought, according to new research coauthored by Paula Shireman, M.D., M.S., M.B.A., of UT Health San Antonio. The journal JAMA Surgery published the findings Nov. 13.

13 Nov 2019

Bacteriophages could treat E. coli without damaging the gut, new study says

Researchers in the US have developed a new therapy that uses a unique bacteriophage to treat E. coli infections.

13 Nov 2019

Novel dental informatics program to improve oral health for better overall health

With the goal of improving oral health for better overall physical and emotional health, Regenstrief Institute and Indiana University School of Dentistry are joining together to establish a novel dental informatics program.

12 Nov 2019

Pervasive gender imbalance remains in pediatric medicine

Three commonly argued justifications for the persistent discrimination and gender bias that prevent women from rising to leadership positions in the field of pediatric medicine have been debunked by a Drexel University College of Medicine researcher and colleagues in a special article published in the November 2019 issue of the journal Pediatrics.

11 Nov 2019

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor inhibitors first.

11 Nov 2019

Common muscle relaxant linked to severe confusion in patients with kidney dysfunction

One in 25 patients with very low kidney function were admitted to hospital with severe confusion and other cognitive-related symptoms a few days after being prescribed a common muscle relaxant.

10 Nov 2019

Study finds reliable biomarker for noninvasive detection of deadly infant disease

A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis.

8 Nov 2019

Researchers join forces to adapt novel genetic tool for zoonotic Chlamydia

The human pathogenic bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide.

7 Nov 2019

Myocardial infarction model developed using cardiomyocytes

Researchers at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences developed a model of myocardial infarction using cardiomyocytes differentiated from human induced pluripotent stem cells.

7 Nov 2019

Rapamycin prevents age-related brain vascular deterioration, study shows

A just-released study by UT Health San Antonio and collaborating institutions shows age-related decreases in blood flow to the brain and memory loss can be modified with the drug rapamycin.

6 Nov 2019

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

The use of nanoparticles to deliver a drug into specific nerve cells has resulted in significantly improved pain relief.

5 Nov 2019

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

An international team of researchers has used nanoparticles to deliver a drug- one that previously failed in clinical trials for pain- into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats.

4 Nov 2019

Probiotics could potentially stave off common bacterial hive infestation

Probiotics, beneficial microorganisms best known for promoting gut health in humans, are now being used by Western University and Lawson Health Research Institute scientists to save honey bee colonies from collapse.

1 Nov 2019

Study: Diagnosed levels of psychosis and anxiety more severe among men in Hackney

Excess psychosis diagnoses amongst Black and South Asian men in deprived urban areas could reflect a cluster of disadvantage in specific places, rather than individual experiences of deprivation alone, a study led by Queen Mary University of London researchers concludes.

30 Oct 2019

Gait disorders can help predict future cognitive decline

The way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to the Journal of Alzheimer's Disease say that gait disorders, particularly slowing gait, should be considered a marker of future cognitive decline.

28 Oct 2019