Endocrinology News and Research

Latest Endocrinology News and Research

New guidelines for accurate diagnosis, effective ethical treatment of postmenopausal osteoporosis

Today the American Association of Clinical Endocrinologists released new medical guidelines for the accurate diagnosis and effective ethical treatment of postmenopausal osteoporosis in affected patients.

11 Jan 2011

All fat cells not the same

All fat cells are not the same - a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).

10 Jan 2011

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

Exelixis, Inc. today announced that the U.S. Food & Drug Administration (FDA) has granted orphan drug designation to XL184 for treatment of follicular, medullary, and anaplastic thyroid carcinoma, and metastatic or locally advanced papillary thyroid cancer. A pivotal phase 3 trial of XL184 is ongoing in patients with medullary thyroid cancer (MTC) and the company expects to release top-line phase 3 results in the first-half of 2011 and potentially file a New Drug Application (NDA) for the compound in the second-half of 2011.

10 Jan 2011

Endo Pharmaceuticals receives FDA complete response letter for OPANA ER

Endo Pharmaceuticals today announced that it received a complete response letter from the U.S. Food and Drug Administration regarding the New Drug Application for its new formulation of OPANA® ER designed to be crush resistant.

10 Jan 2011

AHRQ study shows 19 million U.S. adults received diabetes treatment in 2007

Approximately 19 million U.S. adults reported receiving treatment for diabetes in 2007, more than double the 9 million who said they received care in 1996, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

10 Jan 2011

Anchor announces rapid progress in OMJPI collaboration for developing GPCR therapeutic compounds

Anchor Therapeutics today announced that it has successfully completed the first stage of its collaboration and license agreement with Ortho-McNeil-Janssen Pharmaceuticals.

10 Jan 2011

U-M lab ranks No. 1 in protein structure and function prediction in scientific competition

The University of Michigan Health System took top honors in the Critical Assessment of Techniques for Protein Structure Prediction, a biennial scientific competition to test protein structure and function prediction methods developed by laboratories all over the world.

10 Jan 2011

Study finds link between nonalcoholic fatty liver disease and stroke

People suffering from fatty liver disease may be three times more likely to suffer a stroke than individuals without fatty liver, according to a study by researchers at St. Michael's Hospital and the London Health Sciences Centre.

10 Jan 2011

Gigantism gene inherited by hundreds: Study

A gene that predicted gigantism in humans was identified in the DNA of the 18th-century man known as the Irish Giant, who was more than 7 feet 7 inches tall. Copies of the same mutation have been found in patients today who suffer from excessive growth, and scientists have concluded they all inherited the gene from a common ancestor.

9 Jan 2011

PCPs and kidney specialists favor collaborative care for progressive chronic kidney disease

Most primary care physicians (PCPs) and kidney specialists favor collaborative care for a patient with progressive chronic kidney disease (CKD), but their preferences on how and when to collaborate differ, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). PCPs and kidney specialists need to partner more effectively to optimize care for patients with CKD.

7 Jan 2011

Scientists identify type of cell at the origin of brain tumors

Scientists have identified the type of cell that is at the origin of brain tumors known as oligodendrogliomas, which are a type of glioma - a category that defines the most common type of malignant brain tumor.

7 Jan 2011

FDA approved KOMBIGLYZE XR for type 2 diabetes mellitus now available in pharmacies

Bristol-Myers Squibb Company, and AstraZeneca today announced that KOMBIGLYZE™ XR (saxagliptin and metformin HCl extended-release), approved by the U.S. Food and Drug Administration (FDA) on November 5, 2010, is now available by prescription in pharmacies across the United States.

7 Jan 2011

Plexxikon, Genentech enter PLX4032 co-promotion agreement

Plexxikon, Inc., announced today that it has signed an agreement with Genentech to co-promote PLX4032 (RG7204) in the United States. PLX4032, an oral, novel kinase inhibitor that targets the oncogenic BRAF mutation, is being tested in late-stage clinical trials for the treatment of metastatic melanoma.

7 Jan 2011

Lower co-payments help companies, workers save health-care costs

Companies can cut health-care costs - for themselves and for their workers - by lowering co-payments on prescription drugs while promoting disease management, according to a comprehensive, three-year study commissioned by the Florida Health Care Coalition (FHCC).

7 Jan 2011

Regular blood test shows pre-diabetes risk factors, reduces treatment costs

A simpler form of testing individuals with risk factors for diabetes could improve diabetes prevention efforts by substantially increasing the number of individuals who complete testing and learn whether or not they are likely to develop diabetes.

7 Jan 2011

Researchers identify genetic mutation responsible for acromegaly disease

An international research team, spearheaded by scientists from the London School of Medicine and Dentistry, has identified the genetic mutation responsible for a disease known as "gigantism" or acromegaly.

7 Jan 2011

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Isis Pharmaceuticals, announced today that it has added two new drugs to its development pipeline, ISIS-FGFR4Rx and ISIS-STAT3Rx.

7 Jan 2011

Liver transplant recipients develop PTMS, face high risk of cardiovascular disease

Researchers from Israel have determined that more than half of liver transplant recipients develop post-transplantation metabolic syndrome, placing them at greater risk for cardiovascular disease.

7 Jan 2011

Lexicon Pharmaceuticals announces clinical trial, mechanistic study results of LX4211

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering breakthrough treatments for human disease, announced data from a recently completed clinical trial and mechanistic study of a solid oral dose formulation for LX4211, a dual inhibitor of sodium-glucose co-transporters 1 and 2 (SGLT1 and SGLT2).

6 Jan 2011

Californians can now access information about local healthcare providers using MyHealthResource

Realizing the New Year's resolution of "good health" could be just a click of the mouse away - even for Californians without adequate health insurance, thanks to a free, online resource from Californians for Patient Care. Using MyHealthResource, available at www.calpatientcare.org, Californians can access information about local healthcare providers that provide primary, dental, vision and mental healthcare services to the uninsured and underinsured.

6 Jan 2011

Endocrinology News and Research

Latest Endocrinology News and Research

New guidelines for accurate diagnosis, effective ethical treatment of postmenopausal osteoporosis

All fat cells not the same

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

Endo Pharmaceuticals receives FDA complete response letter for OPANA ER

AHRQ study shows 19 million U.S. adults received diabetes treatment in 2007

Anchor announces rapid progress in OMJPI collaboration for developing GPCR therapeutic compounds

U-M lab ranks No. 1 in protein structure and function prediction in scientific competition

Study finds link between nonalcoholic fatty liver disease and stroke

Gigantism gene inherited by hundreds: Study

PCPs and kidney specialists favor collaborative care for progressive chronic kidney disease

Scientists identify type of cell at the origin of brain tumors

FDA approved KOMBIGLYZE XR for type 2 diabetes mellitus now available in pharmacies

Plexxikon, Genentech enter PLX4032 co-promotion agreement

Lower co-payments help companies, workers save health-care costs

Regular blood test shows pre-diabetes risk factors, reduces treatment costs

Researchers identify genetic mutation responsible for acromegaly disease

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Liver transplant recipients develop PTMS, face high risk of cardiovascular disease

Lexicon Pharmaceuticals announces clinical trial, mechanistic study results of LX4211

Californians can now access information about local healthcare providers using MyHealthResource

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Endocrinology News and Research

Latest Endocrinology News and Research

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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