Endocrinology News and Research

Latest Endocrinology News and Research

New immunoSEQ bioinformatics software platform helps monitor adaptive immune system

Adaptive TCR Technologies, a biotech firm based in Seattle, WA, announced today the release of its immunoSEQ profiling service and immunoSEQ Analyzer bioinformatics software platform. Together, these tools provide researchers and clinicians the ability to profile and monitor the adaptive immune system at a level of detail that has never before been possible.

21 Oct 2010

Metabolon receives patent for biomarkers to determine PPAR-affecting drugs

Metabolon, Inc., leaders in global metabolomics, biomarker discovery and biochemical analysis, announced today the grant of US Patent 7,807,138 entitled "Biomarkers of Metabolic Responses to Hepatic Drugs". The USPTO awarded the patent to Metabolon on October 5, 2010. This is the 13th patent issued to Metabolon and the second in its portfolio of biomarker patents.

21 Oct 2010

Access submits additional patent applications for Cobalamin-mediated oral drug delivery technology

ACCESS PHARMACEUTICALS, INC., a biopharmaceutical company leveraging its proprietary drug-delivery platforms to develop treatments in areas of oncology, cancer supportive care and diabetes, announced it has submitted additional patent applications, covering its Cobalamin-mediated oral drug delivery technology formulations of many global top-100 injectable drugs, as a result of the growing interest surrounding the company's proprietary oral delivery technology.

21 Oct 2010

Generex announces participation in Annual Canadian Diabetes Association Conference

Generex Biotechnology Corporation today announced that it will be attending the 13th Annual Canadian Diabetes Association (CDA)/ Canadian Society of Endocrinology and Metabolism (CSEM)Professional Conference and Annual Meetings in Edmonton, Alberta. The gathering will run from October 20-23, 2010 at the Shaw Conference Centre.

21 Oct 2010

DMC concludes Protege Phase 3 clinical trial for type 1 diabetes lacks efficacy

MacroGenics, Inc. and Eli Lilly and Company today announced that the Protege Data Monitoring Committee (DMC), composed of independent experts in the fields of diabetes and biostatistics, has completed a planned analysis of one-year safety and efficacy data of the Protege Phase 3 clinical trial of teplizumab, an investigational biologic under development for the treatment of individuals with recent-onset type 1 diabetes.

21 Oct 2010

Link between low testosterone and heart disease deaths: Study

In a new study it was seen that men diagnosed with coronary heart disease with low testosterone were almost twice as likely to die over a seven year period. The team led by Prof Kevin Channer a cardiologist of the Royal Hallamshire Hospital in Sheffield looked at 930 men for the study. This study is in contrast to the popular belief that testosterone increases heart disease risk. The study was published in the journal Online First Heart.

21 Oct 2010

Joint stem cell study to investigate multiple sclerosis

A $2.2 million project by Victorian and Californian researchers will assess whether stem cell therapies can be used to combat diseases such as Multiple Sclerosis and Type-1 diabetes, and help organ transplant recipients. Speaking at AusBiotech 2010 in Melbourne today, Innovation Minister Gavin Jennings said the Brumby Labor Government had contributed $575,505 to the project, the fifth to be funded through the $28 million Victoria–California Stem Cell Alliance which was established in 2008 under the Biotechnology Strategic Development Plan.

21 Oct 2010

FDA issues complete response letter for BYDUREON NDA

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter regarding the New Drug Application (NDA) for BYDUREON™ (exenatide extended-release for injectable suspension).

21 Oct 2010

Genzyme third quarter revenue increases to $1.0 billion

Genzyme Corp. today reported third-quarter earnings growth driven by increased shipments of Cerezyme® (imiglucerase for injection). Patients in the United States began returning to normal dosing levels last month, and patients globally are expected to be able to do so this quarter. Earnings growth in the third quarter was also driven by strong revenue from Lumizyme™ (alglucosidase alfa) and cost reduction measures.

21 Oct 2010

NHS needs £20bn of efficiency savings

Britain’s NHS would become one of only two government departments not to face budget cuts in the latest spending review. However some key features have been removed. This includes one-week wait for cancer diagnosis and free prescriptions for people with long-term illnesses.

20 Oct 2010

Overweight dads may pass on diabetes to their daughters: Study

According to a latest study fathers on a high-fat diet are more likely to produce daughters with a higher diabetes risk. The study was published in the journal Nature and it involved laboratory rats.

20 Oct 2010

Health Impact Project announces $400,000 in grants to 4 organizations to conduct health impact assessments

The Health Impact Project, a collaboration of the Robert Wood Johnson Foundation and The Pew Charitable Trusts, today announced nearly $400,000 in grants to four organizations to conduct health impact assessments (HIAs). The assessments will identify and address potential and often overlooked health implications of policy proposals including farm-to-school food legislation, energy development, smart-metering technology for electric utilities and urban transportation plans.

20 Oct 2010

CIGNA plans help reduce annual health care costs without compromising care

When Americans engage in health-smart habits such as participating in health coaching and disease management programs, substituting generic medications for brand name drugs and avoiding unnecessary trips to the emergency room, their total medical costs went down 15 percent -- an average $358 per person in the first year -- according to a new multi-year study comparing the health care claims experience of 897,000 CIGNA customers in consumer driven health (CDH) plans, PPOs and HMOs.

20 Oct 2010

European Commission grants Ipsen's OBI-1 orphan drug status for treatment of hemophilia

Ipsen announced today that the European Commission has granted orphan drug status for OBI-1 for the treatment of hemophilia. Expected to enter pivotal clinical trials before the end of this year, OBI-1 is designed to treat individuals with hemophilia who have developed inhibitory antibodies (inhibitors) against human Factor VIII (hFVIII).

20 Oct 2010

First in vivo screening system for complete human nuclear hormone receptor family

The InDanio screening system can be used, for example, to functionally characterize 'orphan' receptors - those for which their natural ligands or specific function are unknown - and thus qualify them as potential targets for drug discovery. The system can also be used to screen compound libraries in order to identify and refine potential new drugs that target NR proteins.

20 Oct 2010

New approaches to explore causes of autoimmunity and immune deficiency diseases

A newly identified regulatory process affecting the biology of immune system T cells should give scientists new approaches to explore the causes of autoimmunity and immune deficiency diseases.

20 Oct 2010

Aspirin before cardiac surgery reduces postoperative cardiocerebral complications

A study presented at the American Society of Anesthesiologists 2010 Annual Meeting revealed that use of aspirin before cardiac surgery reduced postoperative cardiocerebral complications, including stroke, myocardial ischemia, heart block and cardiac arrest by more than 33 percent when compared to patients who did not use aspirin.

20 Oct 2010

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Because of impairments in their insulin sensitivity, obese individuals demonstrate different brain responses than their normal-weight peers while completing a challenging cognitive task, according to new research by psychologists at The University of Texas at Austin.

20 Oct 2010

Jefferson researchers progress in understanding mechanism behind systemic fibrotic disorder

Scientists from the Jefferson Institute of Molecular Medicine of Thomas Jefferson University are now several steps closer to understanding the mechanism behind a novel systemic fibrotic disorder that affects some patients with renal insufficiency who receive imaging contrast agents for MRI. Two of their studies on the disorder appear together in the November issue of the Annals of Rheumatic Diseases.

20 Oct 2010

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

New findings by UT Southwestern Medical Center researchers suggest a novel role for the brain in mediating beneficial actions of the hormone leptin in type 1 diabetes.

20 Oct 2010

Endocrinology News and Research

Latest Endocrinology News and Research

New immunoSEQ bioinformatics software platform helps monitor adaptive immune system

Metabolon receives patent for biomarkers to determine PPAR-affecting drugs

Access submits additional patent applications for Cobalamin-mediated oral drug delivery technology

Generex announces participation in Annual Canadian Diabetes Association Conference

DMC concludes Protege Phase 3 clinical trial for type 1 diabetes lacks efficacy

Link between low testosterone and heart disease deaths: Study

Joint stem cell study to investigate multiple sclerosis

FDA issues complete response letter for BYDUREON NDA

Genzyme third quarter revenue increases to $1.0 billion

NHS needs £20bn of efficiency savings

Overweight dads may pass on diabetes to their daughters: Study

Health Impact Project announces $400,000 in grants to 4 organizations to conduct health impact assessments

CIGNA plans help reduce annual health care costs without compromising care

European Commission grants Ipsen's OBI-1 orphan drug status for treatment of hemophilia

First in vivo screening system for complete human nuclear hormone receptor family

New approaches to explore causes of autoimmunity and immune deficiency diseases

Aspirin before cardiac surgery reduces postoperative cardiocerebral complications

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Jefferson researchers progress in understanding mechanism behind systemic fibrotic disorder

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Endocrinology News and Research

Latest Endocrinology News and Research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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