Endocrinology News and Research

Latest Endocrinology News and Research

Vitamin D deficiency could lead to heart problems

Vitamin D deficiency - which is traditionally associated with bone and muscle weakness - may also increase the risk of cardiovascular disease (CVD).

1 Dec 2008

Genaera starts trial of Trodusquemine in overweight and obese type 2 diabetes

Genaera Corporation has announced that dosing of subjects has begun in study MSI-1436C-102 (Study 102), the multiple ascending dose Phase 1b study of trodusquemine (MSI-1436) in overweight and obese type 2 diabetics.

1 Dec 2008

Coronary CTA is a low cost, non-invasive alternative for evaluating coronary artery disease

Coronary CTA offers a low cost, non-invasive alternative to conventional angiography for evaluating patients who are suspected of having coronary artery disease; true even if the patients have calcified coronary artery plaques, according to a study performed at the Thomas Jefferson University Hospital, Philadelphia, PA.

1 Dec 2008

Antibiotics causing most drug-induced liver injury

Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute.

1 Dec 2008

Diet may regulate obesity health risks, but genes decide, says new research

The risk of obese people developing the metabolic syndrome that leads to diabetes, hypertension, and heart disease, can not be solved by a one-size-fits-all diet programme, according to new scientific findings.

1 Dec 2008

Scientists hope European grant can improve healthy ageing

Researchers hope to achieve healthy ageing by enhancing body healing capacity and reducing chronic inflammation.

1 Dec 2008

Eli Lilly withdraws application for additional U.S. indication for Cymbalta for chronic pain

Eli Lilly and Company has withdrawn its supplemental New Drug Application (sNDA) from the U.S. Food and Drug Administration (FDA) for Cymbalta (duloxetine HCl) for the management of chronic pain.

30 Nov 2008

Genetic variation in metabolism identified

Metabolic diseases - in particular the increasingly prevalent type 2 diabetes - are caused by a complex interaction between genetic disposition and unfavorable lifestyle, above all unbalanced diet and too little physical exercise.

30 Nov 2008

Study identifies genetic variants giving rise to differences in metabolism

Common genetic polymorphisms induce major differentiations in the metabolic make-up of the human population, according to a paper published November 28 in the open-access journal PLoS Genetics.

28 Nov 2008

Vitamin K appears to slow development of insulin resistance in elderly men

Vitamin K slowed the development of insulin resistance in elderly men in a study of 355 non-diabetic men and women ages 60 to 80 who completed a three-year clinical trial at the Jean Mayer Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA).

26 Nov 2008

Researchers uncover a critical link between taste and body weight

Obesity gradually numbs the taste sensation of rats to sweet foods and drives them to consume larger and ever-sweeter meals, according to neuroscientists.

26 Nov 2008

Researchers identify a potentially universal mechanism of aging

Like our current financial crisis, the aging process might also be a product excessive deregulation.

26 Nov 2008

Researchers identify molecule that tells your brain your stomach is full

In studies with mice and rats, researchers have found that a chemical messenger called NAPE is made in the small intestine after the animals ate a greasy meal. After eating, NAPE - N-acylphosphatidylethanolamine, a mouthful in itself -- enters the blood and travels to the brain, where it quashes hunger signals.

26 Nov 2008

Generic drug competition benefits Ontarians

Following yesterday's release of the Competition Bureau's report, "Benefiting from Generic Drug Competition in Canada: The Way Forward," the Ontario Pharmacists' Association (OPA) is emphasizing that competition in the generic drugs industry is already benefiting Ontarians through accessible, high quality, cost-effective professional pharmacy care.

26 Nov 2008

Fear of hypoglycemia a barrier to exercise for type 1 diabetics

According to a new study, published in the November issue of Diabetes Care , a majority of diabetics avoid physical activity because they worry about exercise-induced hypoglycemia (low blood sugar) and severe consequences including loss of consciousness.

26 Nov 2008

Study examines medical cost increases for individuals living with diabetes

People diagnosed with diabetes spend over $4,100 more each year on medical costs than people who don't have diabetes, a gap that increases substantially each year following the initial diagnosis, according to a study published online today in the journal Diabetes Care.

25 Nov 2008

Genetic variation for persons with diabetes linked to greater risk of coronary artery disease

Patients with type 2 diabetes who have poor glycemic control and a certain genetic variation have an increased risk of coronary artery disease, according to a study in the November 26 issue of JAMA, the Journal of the American Medical Association.

25 Nov 2008

Drink tea instead of soft drinks to avoid tooth erosion

Today, the average size soft drink is 20 ounces and contains 17 teaspoons of sugar.

25 Nov 2008

Declines in cancer incidence and death rates across U.S.

A new report from the nation's leading cancer organizations shows that, for the first time since the report was first issued in 1998, both incidence and death rates for all cancers combined are decreasing for both men and women, driven largely by declines in some of the most common types of cancer.

25 Nov 2008

Presence of gum disease may help dentists and physicians identify risk of cardiovascular disease

Individuals reporting a history of periodontal disease were more likely to have increased levels of inflammation, a risk factor for heart disease, compared to those who reported no history of periodontal disease, according to an American Journal of Cardiology report available online today.

25 Nov 2008