Endocrinology News and Research

Latest Endocrinology News and Research

Why transplanted insulin cells die

New research can enhance survival of islets transplants and improve treatment of type 1 diabetes. Transplantation of insulin-producing cell islets, so-called islets of langerhans is an appealing strategy for treatment of type 1 diabetes. But it turns out that these are short-lived, and the procedure needs to be repeated.

28 Aug 2008

Transformation of ordinary cells into insulin-makers improves symptoms of diabetes

Scientists in the U.S. have successfully transformed ordinary cells into insulin-producing cells in a living mouse and thereby improved the symptoms of diabetes.

28 Aug 2008

Young type-2 diabetic men suffer low testosterone levels

Young men with type 2 diabetes have significantly low levels of testosterone, endocrinologists at the University at Buffalo have found -- a condition that could have a critical effect on their quality of life and on their ability to father children.

27 Aug 2008

Chronic stress alters our genetic immune response

Most people would agree that stress increases your risk for illness and this is particularly true for severe long-term stresses, such as caring for a family member with a chronic medical illness. However, we still have a relatively limited understanding of exactly how stress contributes to the risk for illness. In the August 15th issue of Biological Psychiatry, researchers shed new light on one link between stress and illness by describing a mechanism through which stress alters immune function.

27 Aug 2008

Early trigger for type-1 diabetes found in mice

Scientists at the Stanford University School of Medicine are shedding light on how type-1 diabetes begins.

26 Aug 2008

VioQuest Pharmaceuticals issued new U.S. patent for Lenocta

VioQuest Pharmaceuticals today announced that the United States Patent and Trademark Office has issued the first patent for the company's investigational product candidate Lenocta (sodium stibogluconate). U.S. Patent No. 7,416,723 entitled "Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases," encompasses novel compositions including Lenocta for the treatment of cancer and a broad range of other diseases.

26 Aug 2008

Caesarean babies at risk of diabetes

New research from the UK is suggesting that babies born by Caesarean section have a 20% higher risk of developing type 1 diabetes.

26 Aug 2008

NicOx updates on PF-03187207 and research collaboration with Pfizer

NicOx S.A. has announced the results of a dose-ranging phase 2 study conducted with PF‑03187207 in Japanese patients with glaucoma by its partner Pfizer Inc. PF-03187207 is a nitric oxide-donating prostaglandin analog. The study was designed to compare the safety and efficacy of several doses of PF-03187207 to Xalatan (latanoprost) and enrolled 112 Japanese patients with primary open-angle glaucoma or ocular hypertension.

25 Aug 2008

UT Southwestern scientists discover leptin can also aid type 1 diabetics

Terminally ill rodents with type 1 diabetes have been restored to full health with a single injection of a substance other than insulin by scientists at UT Southwestern Medical Center.

25 Aug 2008

Daily aspirin recommended for all middle-aged

Researchers in the UK say that taking an aspirin each day could prevent heart attacks in middle-age.

25 Aug 2008

Novel imaging reagents and technology that non-invasively locates, quantifies specific cells in the body

Magnetic resonance imaging (MRI) isn't just for capturing detailed images of the body's anatomy. Thanks to novel imaging reagents and technology developed by Carnegie Mellon University scientist Eric Ahrens, MRI can be used to visualize - with "exquisite" specificity - cell populations of interest in the living body. The ability to non-invasively locate and track cells, such as immune cells, will greatly aid the study and treatment of cancer, inflammation, and autoimmune diseases, as well as provide a tool for advancing clinical translation of the emerging field of cellular regenerative medicine, by tracking stem cells for example.

21 Aug 2008

Brown fat points to new ways to fight obesity

A surprise discovery -- that calorie-burning brown fat can be produced experimentally from muscle precursor cells in mice -- raises the prospect of new ways to fight obesity and overweight, say scientists from Dana-Farber Cancer Institute.

20 Aug 2008

Bone marrow stem cells used to protect gastrointestinal tissue from autoimmune attack

Massachusetts General Hospital (MGH) investigators have found that infusions of a particular bone marrow stem cell appeared to protect gastrointestinal tissue from autoimmune attack in a mouse model.

20 Aug 2008

New research suggests inherited diabetes may play a role in rising rates

A new study in the September issue of the Journal of Lipid Research suggests an unusual form of inheritance may have a role in the rising rate of diabetes, especially in children and young adults, in the United States.

20 Aug 2008

Warning issued on dangers of diabetes drug Avandia

Thousands of Australians who are taking the diabetes drug Avandia (rosiglitazone) have been urged by the drug's manufacturer to see their doctors following safety issues concerning the medication.

20 Aug 2008

Type 2 diabetes linked to arsenic in drinking water

While exposure to high concentrations of the element in drinking water and in the workplace has been shown to be associated with diabetes, little is known about the effect of lower levels on diabetes risk.

20 Aug 2008

Inorganic arsenic may increase the risk of developing type 2 diabetes

Inorganic arsenic, commonly found in ground water in certain areas, may increase the risk of developing type 2 diabetes, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.

19 Aug 2008

Are your eyes a window to diabetes-related health issues?

Scientists at Aston University in Birmingham, UK are carrying out a unique study using the eyes to detect early signs of health problems which could lead to diabetes, and they're looking for volunteers to help.

19 Aug 2008

Top Sydney hospital appoints specialist to treat childhood obesity

As Australian children appear to be getting increasingly overweight one of the country's top hospitals has taken the apparently unprecedented step of appointing a specialist to treat childhood obesity.

18 Aug 2008