Endocrinology News and Research

Latest Endocrinology News and Research

Discovery of gene that appears to play an important role in the onset of type 2 diabetes

In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.

8 May 2006

Urgent effort underway to learn how diabetes increases heart disease risk

A researcher at the University of Rochester Medical Center has won the 2006 Thomas R. Lee Career Development Award from the American Diabetes Association (ADA), which includes an $842,400 grant to study how diabetes dramatically increases risk for cardiovascular disease.

8 May 2006

Cancer cure worth $50 trillion

A new study, to be published in a forthcoming issue of the Journal of Political Economy, calculates the prospective gains that could be obtained from further progress against major diseases.

3 May 2006

Death risks high in younger people with diabetes

People with Type 2 diabetes aged between 35 and 54 are over three times more likely to die than those without the condition according to research published in the journal Diabetic Medicine.

3 May 2006

Endocannabinoid system shows promise in combating obesity

As the obesity epidemic grows in the United States, the medical community is faced with the significant challenge of properly treating patients before complications such as heart disease arise.

3 May 2006

Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the U.S.

A new study on the relationship between nonalcoholic fatty liver disease (NAFLD) and heart disease found that patients with an elevated level of the enzyme associated with NAFLD had an increased risk of coronary heart disease, which appears to be related to insulin resistance, obesity and central fat distribution.

3 May 2006

Study highlights the benefits of a clinic that specializes in the needs of obese patients with metabolic syndrome

Obesity researchers at the Medical College of Wisconsin in Milwaukee found that a multidisciplinary clinical approach to caring for obese patients with metabolic syndrome could swiftly and significantly lower their risk for heart disease.

3 May 2006

Dimensional analysis of the concept of obesity

Health professionals need to use more than tape measures and scales to define and tackle obesity, according to a paper in the latest Journal of Advanced Nursing.

3 May 2006

The 30-year natural history of type 1 diabetes complications

...while cases of premature death and a few other complications have declined, rates of other serious diabetes-related disorders such as heart and eye disease have not improved over the past 25 to 30 years.

3 May 2006

British healthier than Americans in middle-age

According to a large international study middle-aged Americans are not as healthy as their British cousins.

2 May 2006

Kidney patients warned away from potassium

Many kidney failure patients are increasing their chance of nerve damage in their legs and feet by simply having too much potassium in their diet, according to research carried out by the University of New South Wales (UNSW), the Prince of Wales Medical Research Institute (POWMRI) and the Prince of Wales Hospital.

2 May 2006

Combinatorial approach found to reverse the onset of type 1 diabetes

A major finding, which represents an important step toward a potential cure for type 1 (insulin-dependent) diabetes, has been made by a research team at the La Jolla Institute for Allergy & Immunology (LIAI). The team, led by Matthias von Herrath, M.D., an internationally recognized expert on the molecular basis of type 1 diabetes, used a combinatorial treatment approach in laboratory mice and found it reversed recent onset type 1 diabetes in the majority of animals tested.

28 Apr 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Osteoporosis could be caused by factors other than declining estrogen levels

New evidence in the April 21, 2006 Cell challenges the long-standing notion that declining estrogen levels alone lead to osteoporosis after women go through menopause. The researchers rather found that high levels of pituitary-derived follicle-stimulating hormone (FSH) cause bone loss in mice. The pituitary is a master gland found at the base of the brain.

26 Apr 2006

Preconception health care should be part of routine medical visits

Every visit to the doctor for women of childbearing age should be considered an opportunity to discuss reproductive health- especially since more than half of all pregnancies are unintended, according to a report published today in the U.S. Centers for Disease Control and Prevention's journal Morbidity and Mortality Weekly Report Recommendations and Reports.

26 Apr 2006

Preconception health care should be part of routine medical visits

26 Apr 2006

Evidence explains relationship between television and poor diet in children

Researchers from the Harvard School of Public Health (HSPH) and Children's Hospital Boston found that kids who spend more time watching television also eat more of the calorie-dense, low-nutrient foods advertised on television. Previous studies had demonstrated that children who watch more television are more likely to be overweight, but this is the first time a research team has found evidence for a mechanism explaining that relationship.

26 Apr 2006

Protein mutated in cancer found to be linked to diabetes

A study published by Nature has defined the function of p110 alpha, the flag-ship molecule of the eight member PI3K family, which is one of the most frequently activated pathways in cancer. The function of p110 alpha in the body has eluded researchers for over a decade but a new approach to generating mouse models, has allowed investigators to solve the mystery and yield important information for planned clinical trials with PI3K inhibitors.

25 Apr 2006

Study shows drugs work differently in the brains of men and women

A Johns Hopkins discovery could lead to tailored treatments for drug abuse and neurological diseases after providing what is believed to be the first evidence in people that amphetamines have a greater effect on men's brains than women's.

24 Apr 2006

Direct link between childhood obesity and junk food advertising

A team of researchers from the Harvard School of Public health (HSPH) and the Children's Hospital in Boston have found that children who spend more time watching TV were more likely to eat more of the calorie-dense, low nutrient foods advertised on television.

24 Apr 2006