Endocrinology News and Research

Latest Endocrinology News and Research

Simple lifestyle intervention can help prevent gestational diabetes in high-risk women

Gestational diabetes can be prevented by a simple, easily applicable individualized lifestyle intervention in high-risk women, finds a study led by Helsinki University Hospital and South Karelia Central Hospital, Finland. The results of the study are promising, and in line with previous published T2D prevention studies. The findings may have major health consequences for both the mother and the child.

31 Jul 2015

Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

Takeda Pharmaceutical Company Limited today announced the completion of the study to fulfill the post-marketing commitment and submissions of data to regulatory authorities from the Pan European Multi-Database Bladder Cancer Risk Characterization Study, a large (n= 112,674), multi-database retrospective matched cohort study, conducted in four European countries, for pioglitazone containing medicines, including ACTOS with up to 10 years of follow-up.

31 Jul 2015

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart of the School of Science, have received a $2.6 million grant from the National Institutes of Health to conduct the first randomized controlled trial to determine whether depression treatment can help prevent the development of cardiovascular disease.

31 Jul 2015

IBM, CVS Health to transform care management services for patients with chronic disease

CVS Health (NYSE: CVS) and IBM today announced they will use predictive analytics and Watson cognitive computing to transform care management services for patients with chronic disease.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

Isis Pharmaceuticals, Inc., the leader in RNA-targeted therapeutics, and Akcea Therapeutics, its wholly owned subsidiary, announced today that The New England Journal of Medicine (NEJM) has published positive clinical results from a Phase 2 clinical study evaluating volanesorsen (formerly ISIS-APOCIII Rx) in patients with very high to severely high triglycerides.

30 Jul 2015

Blocking the expression of certain gene reduces excessive fat in patients

By blocking the expression of a certain gene in patients, University of Montreal researchers have contributed to the demonstration of great decreases in the concentration of triglycerides in their blood, even in various severe forms of hypertriglyceridemia and regardless of the base values or the treatment the patient usually receives.

30 Jul 2015

Low blood level of 4 proteins can help diabetics protect against immune attack

Patients with type 1 diabetes have significantly lower blood levels of four proteins that help protect their tissue from attack by their immune system, scientists report.

30 Jul 2015

Endocrine Society recommends removal of tumor as first-line treatment for endogenous Cushing's syndrome

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for treating Cushing's syndrome, a condition caused by overexposure to the hormone cortisol.

30 Jul 2015

Aeterna Zentaris selects optimized Erk inhibitor molecule for further development

Aeterna Zentaris Inc. today announced it has selected an optimized Erk inhibitor molecule for development, thus achieving another important milestone in the development of a new class of potential cancer therapies.

29 Jul 2015

LixiLan-O Phase III clinical trial meets primary endpoint in patients with type 2 diabetes

Sanofi announced today that the LixiLan-O Phase III clinical trial met its primary objective in patients with type 2 diabetes treated with metformin. The fixed-ratio combination of insulin glargine 100 units/mL and lixisenatide, a GLP-1 RA, demonstrated statistically superior reduction in HbA1c (average blood glucose over the previous three months) compared with lixisenatide and compared with insulin glargine 100 units/mL.

29 Jul 2015

IOF, EOS to jointly hold Middle East & Africa Osteoporosis Meeting in Abu Dhabi

With a growing senior population and an increase in unhealthy lifestyles, the prevalence of osteoporosis and Type 2 Diabetes Mellitus is soaring in the Middle East and North African region. In response to the dramatic increase in these diseases within the region the International Osteoporosis Foundation, in cooperation with the Emirates Osteoporosis Society, will be holding the 3rd Middle East & Africa Osteoporosis Meeting from December 5-7, 2015 in Abu Dhabi.

29 Jul 2015

BioCision signs deal to develop CoolCell freezing systems for Cook Regentec’s CellSeal vials

BioCision, LLC today announced that they have entered into an exclusive partnership with Cook Regentec to develop two custom CoolCell controlled-rate cell freezing systems for Cook’s closed-system cell therapy CellSeal vials.

29 Jul 2015

‘Digital Doctor’ study examines attitudes of primary care physicians to new healthcare technologies

Healthcare apps and wearable tech have a long future in the treatment of patients, according to a panel of Primary Care Physicians (PCPs) interviewed as part of a newly launched Ipsos Healthcare study.

29 Jul 2015

New study estimates link between coffee consumption habits and incidence of mild cognitive impairment

A new study by researchers at the University of Bari Aldo Moro, Bari, Italy, Geriatric Unit & Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy, and Istituto Superiore di Sanità, Roma, Italy, estimates the association between change or constant habits in coffee consumption and the incidence of mild cognitive impairment (MCI), evaluating 1,445 individuals recruited from 5,632 subjects, aged 65-84 year old, from the Italian Longitudinal Study on Aging (ILSA), a population-based sample from eight Italian municipalities with a 3.5-year median follow-up.

29 Jul 2015

UC Davis health economists predict total costs of caring for individuals with ASD in the U.S.

UC Davis health economists have for the first time projected the total costs of caring for all people with autism spectrum disorder (ASD) in the U.S. for the current calendar year and in 10 years if effective interventions and preventive treatments for the condition are not identified and widely available.

29 Jul 2015

New Tel Aviv University study reveals impact of skipping breakfast on the health of diabetics

More and more Americans on-the-go are skipping the "most important meal of the day," not eating until lunch. This tendency to miss breakfast has already been linked to the growing epidemic of obesity and cardiovascular problems in the US -- and it may put the health of diabetics at risk as well.

29 Jul 2015

German life sciences entrepreneurs granted option to develop Aeterna Zentaris’ oral allogenic tumor vaccine technology

Aeterna Zentaris Inc. today announced that it has granted to German life sciences entrepreneurs with a proven track-record of funding the development and commercialization of biotechnology, an option to license the Company's live recombinant oral allogenic tumor vaccine technology, including AEZS-120, the most advanced product candidate for prostate cancer which is ready to enter a Phase 1 clinical trial.

28 Jul 2015

IU awarded $4.5 million NIH grant to create new federally designated diabetes research center

The National Institutes of Health has awarded the Indiana University School of Medicine a five-year, $4.5 million grant to create a new federally designated Indiana Diabetes Research Center, one of just 16 such centers in the country.

28 Jul 2015

Endocrinology News and Research

Latest Endocrinology News and Research

Simple lifestyle intervention can help prevent gestational diabetes in high-risk women

Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

IBM, CVS Health to transform care management services for patients with chronic disease

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

Blocking the expression of certain gene reduces excessive fat in patients

Low blood level of 4 proteins can help diabetics protect against immune attack

Endocrine Society recommends removal of tumor as first-line treatment for endogenous Cushing's syndrome

Aeterna Zentaris selects optimized Erk inhibitor molecule for further development

LixiLan-O Phase III clinical trial meets primary endpoint in patients with type 2 diabetes

IOF, EOS to jointly hold Middle East & Africa Osteoporosis Meeting in Abu Dhabi

BioCision signs deal to develop CoolCell freezing systems for Cook Regentec’s CellSeal vials

‘Digital Doctor’ study examines attitudes of primary care physicians to new healthcare technologies

New study estimates link between coffee consumption habits and incidence of mild cognitive impairment

UC Davis health economists predict total costs of caring for individuals with ASD in the U.S.

New Tel Aviv University study reveals impact of skipping breakfast on the health of diabetics

German life sciences entrepreneurs granted option to develop Aeterna Zentaris’ oral allogenic tumor vaccine technology

IU awarded $4.5 million NIH grant to create new federally designated diabetes research center

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Endocrinology News and Research

Latest Endocrinology News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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