Endocrinology News and Research

Latest Endocrinology News and Research

Glycan released by parasites might help treat metabolic disorders associated with obesity

On the list of undesirable medical conditions, a parasitic worm infection surely ranks fairly high. Although modern pharmaceuticals have made them less of a threat in some areas, these organisms are still a major cause of disease and disability throughout much of the developing world.

9 Jan 2013

Metabolic stress can increase onset of atrial fibrillation

Researchers have found new evidence that metabolic stress can increase the onset of atrial arrhythmias, such as atrial fibrillation (AF), a common heart condition that causes an irregular and often abnormally fast heart rate.

9 Jan 2013

Tibial artery calcification predicts foot ulceration

Tibial artery calcification is a significant risk factor for foot ulcers in patients with Type 2 diabetes, research suggests.

9 Jan 2013

Overall cancer death rates continue to decline in the U.S.: Report

The Annual Report to the Nation on the Status of Cancer, 1975-2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and rectum, female breast, and prostate.

9 Jan 2013

Lilly, Boehringer Ingelheim announce top-line results from empagliflozin Phase III trials on T2D

Boehringer Ingelheim and Eli Lilly and Company today announced top-line results for four completed Phase III clinical trials for empagliflozin, an investigational sodium glucose co-transporter-2 (SGLT2) inhibitor being studied for treatment of patients with Type 2 Diabetes (T2D).

9 Jan 2013

Combination of pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer

A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine.

9 Jan 2013

Tunisian women more likely to suffer from obesity than male compatriots

Men and women in Tunisia are not equal before the scales. Tunisian women are three times as likely to suffer from obesity as their male compatriots.

9 Jan 2013

Oramed files IND with FDA to begin ORMD-0801 Phase 2 trial for type 2 diabetes

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) to begin a Phase 2 clinical trial of its orally ingested insulin candidate, ORMD-0801.

9 Jan 2013

Orexigen reports progress with FDA on faster path to Contrave NDA resubmission

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced progress with the United States Food and Drug Administration (FDA) on a faster path to resubmission of the Contrave (naltrexone SR / bupropion SR) New Drug Application (NDA).

9 Jan 2013

Study demonstrates effects of obesity on 'Taupathies'

In France, more than 860,000 people suffer from Alzheimer's disease and related disorders, making them the largest cause of age-related loss of intellectual function. Cognitive impairments observed in Alzheimer's disease result from the accumulation of abnormal tau proteins in nerve cells undergoing degeneration . We know that obesity, a major risk factor in the development of insulin resistance and type 2 diabetes, increases the risk of dementia during the aging process.

9 Jan 2013

Babies born to obese mothers have low levels of vitamin D

Women who are obese at the start of their pregnancy may be passing on insufficient levels of vitamin D to their babies, according to a new Northwestern Medicine- study.

8 Jan 2013

Esperion reports positive results from ETC-1002 Phase 2 clinical trial on type 2 diabetes

Esperion Therapeutics, the leading developer of small molecule therapies for the treatment of cardiometabolic disorders, today announced positive results of a recently completed Phase 2 clinical trial of ETC-1002 in patients with type 2 diabetes with LDL-C lowering of up to 43% compared to placebo.

8 Jan 2013

New study finds that adults with diabetes in Ontario get fewer government-funded eye exams

A new study has found that adults with diabetes in Ontario are getting significantly fewer government-funded eye exams than they were a decade ago, a key component of high-quality diabetes care essential to preventing diabetes-related eye complications.

8 Jan 2013

Researchers identify protein that helps prevent obesity

University of Florida researchers and colleagues have identified a protein that, when absent, helps the body burn fat and prevents insulin resistance and obesity.

8 Jan 2013

EHR implementation with technical support can improve patient care in small physician practices: Study

The relationship between a physician practice's adoption of electronic health records (EHR) and quality improvements in patient care remains unclear.

7 Jan 2013

Shoulder complaint linked to diabetes diagnosis

Study findings confirm suspicions that patients with diabetes have an increased risk for adhesive capsulitis of the shoulder.

7 Jan 2013

New insulin associated genetic variants discovered

Exome array genotyping, which allows focus on the protein coding regions of the genome, has enabled researchers to identify three new genes containing low-frequency variants that influence insulin levels.

7 Jan 2013

Periodontal disease may predispose men to impotence

Men in their thirties with chronic gum disease are at significantly increased risk for erectile dysfunction, suggests a study by Turkish researchers.

7 Jan 2013

Root of socioeconomic impact on hypertension pinpointed

People who earn a low wage have a greater risk for hypertension than their counterparts with a higher income, especially women and those aged 25–44 years, research suggests.

7 Jan 2013

Roundup: Texas begins new Women's Health Program; Federal spending uncertainty bedevils states; 'Medi-scare' mailings

Texas is funding the Women's Health Program on its own because the federal government pulled funding after the state blocked Planned Parenthood from participating. The Texas version still serves low-income women who would qualify for Medicaid if they became pregnant. It will cover about 110,000 women between 18 and 44 years old with free well-woman exams, basic health care and certain family planning services.

7 Jan 2013