Endocrinology News and Research

Latest Endocrinology News and Research

Loss of IGSF1 gene function causes central hypothyroidism

Loss of function in the X-linked immunoglobulin superfamily member 1 (IGSF1) gene causes central hypothyroidism, testicular enlargement, and variable prolactin deficiency, according to data presented at the 82nd Annual Meeting of the American Thyroid Association in Québec City, Québec, Canada.

21 Sep 2012

ChromaDex announces findings from pTeroPure Phase 2/3 trial on high blood pressure

ChromaDex Corporation announced today findings from a Phase 2/3 trial at the University of Mississippi Medical Center showing its patented nutritional ingredient pTeroPure (pterostilbene) significantly reduced blood pressure in adults.

21 Sep 2012

Iron transport may contribute to diabetes

Scientists have been trying to explain the causes of diabetes for many years. Researchers at the University of Copenhagen and Novo Nordisk A/S have now shown that the increased activity of one particular iron-transport protein destroys insulin-producing beta cells. In addition, the new research shows that mice without this iron transporter are protected against developing diabetes.

21 Sep 2012

Mathematical modeling can help treat several diseases

Mathematical modeling being tested by researchers at the School of Science at Indiana University-Purdue University Indianapolis (IUPUI) and the IU School of Medicine has the potential to impact the knowledge and treatment of several diseases that continue to challenge scientists across the world.

21 Sep 2012

Childhood emotional neglect may increase risk of stroke in later adulthood

The results from a new study by neurological researchers from the Rush Alzheimer's Disease Center at Rush University Medical Center suggest that people who were emotionally neglected as children may have a higher risk of stroke in later adulthood.

21 Sep 2012

MiR-34a plays a key role in obesity

Scientists have identified a key molecular player in a chain of events in the body that can lead to fatty liver disease, Type II diabetes and other metabolic abnormalities associated with obesity. By blocking this molecule, the researchers were able to reverse some of the pathology it caused in obese mice.

21 Sep 2012

Benefits limited of surgery weight loss for sleep apnea

Obese patients with obstructive sleep apnea who lose significant weight through surgery may still not be cured of their sleep disorder, study findings indicate.

20 Sep 2012

Sweet success healing diabetic foot ulcers

Scientists have harnessed the antibacterial properties of Manuka honey to speed healing of neuropathic diabetic foot ulcers.

20 Sep 2012

Bisphenol A may contribute to childhood obesity

Research published in JAMA demonstrates strong evidence of a link between childhood obesity and bisphenol A exposure.

20 Sep 2012

Gum disease bacteria linked to pancreatic cancer risk

People with high levels of antibodies to bacteria linked to periodontal disease have an increased risk for pancreatic cancer, while the risk is reduced in those with increased antibodies to oral commensal bacteria, say researchers.

20 Sep 2012

GSK3 inhibition protects against gum disease

Treatment with the cell-permeable glycogen synthase kinase -3β-specific enzyme inhibitor SB216763 successfully suppresses alveolar bone loss in mice infected with the main periodontal pathogen, Porphyromonas gingivalis, report researchers.

20 Sep 2012

Lund University professor to coordinate oral insulin study for type 1 diabetes

Type 1 diabetes is the autoimmune form of diabetes, in which the patients' insulin-producing beta cells are destroyed by their own immune system. "We know that if a person has two autoantibodies and one of them is against insulin, there is a 50 per cent risk that they will develop type 1 diabetes within five years. It doesn't matter how old you are", says Ake Lernmark, Professor of Experimental Diabetes Research at Lund University in Sweden.

20 Sep 2012

Views on obesity: Difficulty changing eating habits; Huge changes in the food marketplace

The New York Times and the Journal of the American Medical Association offer opinions on the U.S. battle against obesity.

20 Sep 2012

Report: Obesity rates will continue to grow, causing increases in health care costs, disease incidence

The Robert Wood Johnson Foundation and Trust for America's Health concluded that, based on current trends, most Americans could be obese by 2030.

20 Sep 2012

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S.

20 Sep 2012

Therapeutic video games can show health-related benefits

Can video games help patients with cancer, diabetes, asthma, depression, autism and Parkinson's disease? A new publication by researchers from the University of Utah, appearing in the Sept 19 issue of the journal Science Translational Medicine, indicates video games can be therapeutic and are already beginning to show health-related benefits.

20 Sep 2012

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes mellitus, while obese individuals with higher amounts of total body fat and subcutaneous fat (underneath the skin) did not have this increased risk, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Study examines association of Roux-en-Y gastric bypass surgery with weight loss, diabetes mellitus

Severely obese patients who had Roux-en-Y gastric bypass surgery had significant weight loss that was sustained for an average of 6 years after the surgery and also experienced frequent remission and lower incidence of diabetes, hypertension, and abnormal cholesterol levels, compared to participants who did not have the surgery, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Bariatric surgery reduces long-term risk of diabetes by over 80 % among people with obesity

Bariatric surgery reduces the long-term risk of developing diabetes by over 80 % among people with obesity. The New England Journal of Medicine (NEJM) has published the results of a study conducted at Sahlgrenska Academy, University of Gothenburg, Sweden.

19 Sep 2012

Study finds links between antibodies for multiple oral bacteria and risk of pancreatic cancer

A new study finds significant associations between antibodies for multiple oral bacteria and the risk of pancreatic cancer, adding support for the emerging idea that the ostensibly distant medical conditions are related.

19 Sep 2012