Endocrinology News and Research

Latest Endocrinology News and Research

Takeda resubmits alogliptin and fixed-dose combination therapy NDAs with FDA

Furiex Pharmaceuticals, Inc. today confirmed that Takeda Pharmaceutical Company Limited announced that its wholly-owned subsidiary, Takeda Global Research & Development Center, Inc. has resubmitted New Drug Applications (NDAs) to the U.S. Food and Drug Administration (FDA) for alogliptin and fixed-dose combination therapy alogliptin and pioglitazone for the treatment of type 2 diabetes in adults.

28 Jul 2012

New drug can aid in losing weight and keeping it off

A new drug could aid in losing weight and keeping it off. The drug, described in the journal Cell Metabolism on July 26, increases sensitivity to the hormone leptin, a natural appetite suppressant found in the body. Although so far the new drug has only been tested on mice, the findings have implications for the development of new treatments for obesity in humans.

28 Jul 2012

Roundup: Mass. lawmakers struggle to reach agreement on cost controls; $100M grant for Calif. stem cell research; N.C. to move mentally ill from elderly homes

The House and Senate are under the gun to reach an agreement on how to lower health care costs while improving care. A conference committee aims to have a bill out on Sunday. Their deadline is Monday evening. In the meantime, several major issues are still unresolved, including what to do about hospitals that use their market clout to demand high prices that are not based on higher quality. Attorney General Martha Coakley, the state's top insurers and several consumer groups argue that price is a critical issue.

28 Jul 2012

Long-term linagliptin effective treatment for Type 2 diabetes

Linagliptin is an effective and well-tolerated therapy for the long-term management of Type 2 diabetes, say the authors of an open-label extension study published in the International Journal of Clinical Practice.

27 Jul 2012

Diabetes cutoffs don’t quite cut it for South Asians

Individuals of South Asian origin may require closer monitoring for Type 2 diabetes, suggest researchers.

27 Jul 2012

Novel method of identifying molecules that can help prevent diabetes

Pancreatic beta cells produce insulin, responsible for controlling blood sugar levels and thus essential for our survival. Among the numerous factors that affect the workings of these cells, a protein called Cx36 was identified a few months ago by a research team at the UNIGE.

27 Jul 2012

Heart attack and stroke risk increased with shift work

Shift work is associated with an increased risk of major vascular problems, such as heart attacks and strokes, concludes a study published on bmj.com today.

27 Jul 2012

Coca-Cola sold in California now contains little of cancer-causing chemical 4-methylimidizole

Carcinogenicity and regulation of caramel colorings by Michael Jacobson, (Executive Director, Center for Science in the Public Interest, USA), an article due to be published in the International Journal of Occupational and Environmental Health, states that Coca-Cola sold in California now contains little of the cancer-causing chemical 4-methylimidizole (4-MI).

27 Jul 2012

Viewpoints: AIDS spread in U.S. South; Abortion opponents battle in Ariz.; GOP's costly effort to kill health law

More than 30 years into the AIDS epidemic, a combination of safe-sex education and a new generation of pharmaceuticals has left many Americans convinced that HIV/AIDS is a problem that has been, if not solved, at least addressed. But that's certainly not true in the American South, which accounts for nearly 50% of all new HIV infections in the United States.

27 Jul 2012

A2bAR receptor plays a significant role in regulation of type 2 diabetes and obesity

A recent study led by Boston University School of Medicine (BUSM) demonstrates that the A2b-type adenosine receptor, A2bAR, plays a significant role in the regulation of high fat, high cholesterol diet-induced symptoms of type 2 diabetes.

27 Jul 2012

Biodel to develop ultra-rapid-acting insulin formulations for use in closed loop pump system

Biodel Inc. announced today that the Small Business Innovation Research (SBIR) program of the National Institutes of Health (NIH) has awarded Biodel a grant for the development of concentrated ultra-rapid-acting insulin formulations for use in an artificial pancreas, also known as a closed loop pump system.

27 Jul 2012

Roundup: Ore. Gov. suggests malpractice reform; Mass. Gov. proposes new scrutiny for health care providers; Texas has offered HPV vaccine since 2007

The state can cut health care costs and reduce the number of medical-related lawsuits by requiring earlier notification of injuries as well as pretrial mediation, according to a recommendation Gov. John Kitzhaber issued Wednesday. The product of closed-door talks between representatives of interest groups including the Oregon Medical Association and the Oregon Trial Lawyers Association, Kitzhaber's recommendation now goes to a work group including lawmakers, a trial lawyer and doctor that begins public meetings next week.

27 Jul 2012

Molecular explanation for increased susceptibility to intestinal inflammation in malnutrition

More than one billion people in poor countries are starving, and malnutrition remains a major problem even in rich countries, making it a leading cause of death in the world. For over a hundred years, doctors have known that a lack of protein in the diet or low levels of amino acids, the building blocks of proteins, can lead to symptoms like diarrhoea, inflamed intestines and other immune system disorders, which weaken the body and can be fatal. However, the molecular mechanism which explains how malnutrition causes such severe symptoms has been largely unexplored.

26 Jul 2012

Excess maternal iodine supplementation can lead to congenital hypothyroidism in infants

Congenital hypothyroidism is thyroid hormone deficiency at birth that, if left untreated, can lead to neurocognitive impairments in infants and children. Although the World Health Organization recommends 200-300 -g of iodine daily during pregnancy for normal fetal thyroid hormone production and neurocognitive development, the US Institute of Medicine considers 1,100 -g to be the safe upper limit for daily ingestion.

26 Jul 2012

Diabetic women more likely to report low overall sexual satisfaction

Women with diabetes are just as likely to be interested in, and engage in, sexual activity as non-diabetic women, but they are much more likely to report low overall sexual satisfaction, according to a UCSF study.

26 Jul 2012

Vmersion-Health introduces Gluco-Share app for people with diabetes

Vmersion-Health introduces Gluco-Share, a mobile smart device application that connects people living with diabetes with their family and friends through a private and secure social media network. The Gluco-Share app is a free download available at the Apple iTunes store.

26 Jul 2012

Miriam researchers encourage physicians to inquire about ED symptoms in young, middle-aged men

Although erectile dysfunction (ED) has been shown to be an early warning sign for heart disease, some physicians - and patients - still think of it as just as a natural part of "old age." But now an international team of researchers, led by physicians at The Miriam Hospital, say it's time to expand ED symptom screening to include younger and middle-aged men.

26 Jul 2012

Endocrinology News and Research

Latest Endocrinology News and Research

Takeda resubmits alogliptin and fixed-dose combination therapy NDAs with FDA

New drug can aid in losing weight and keeping it off

Roundup: Mass. lawmakers struggle to reach agreement on cost controls; $100M grant for Calif. stem cell research; N.C. to move mentally ill from elderly homes

Long-term linagliptin effective treatment for Type 2 diabetes

Diabetes cutoffs don’t quite cut it for South Asians

Novel method of identifying molecules that can help prevent diabetes

Heart attack and stroke risk increased with shift work

Coca-Cola sold in California now contains little of cancer-causing chemical 4-methylimidizole

Viewpoints: AIDS spread in U.S. South; Abortion opponents battle in Ariz.; GOP's costly effort to kill health law

A2bAR receptor plays a significant role in regulation of type 2 diabetes and obesity

Biodel to develop ultra-rapid-acting insulin formulations for use in closed loop pump system

Roundup: Ore. Gov. suggests malpractice reform; Mass. Gov. proposes new scrutiny for health care providers; Texas has offered HPV vaccine since 2007

Molecular explanation for increased susceptibility to intestinal inflammation in malnutrition

Excess maternal iodine supplementation can lead to congenital hypothyroidism in infants

Diabetic women more likely to report low overall sexual satisfaction

Vmersion-Health introduces Gluco-Share app for people with diabetes

Miriam researchers encourage physicians to inquire about ED symptoms in young, middle-aged men

Roche Diabetes Care announces availability of new ACCU-CHEK Nano SmartView System

Studies look at surgical site infections and hyperglycemia

Hard work puts stress on the female heart

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

Endocrinology News and Research

Latest Endocrinology News and Research

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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