Endocrinology News and Research

Latest Endocrinology News and Research

Scientists discover why rapamycin causes diabetic-like symptoms in patients

Scientists at Dana-Farber Cancer Institute have discovered why diabetic-like symptoms develop in some patients given rapamycin, an immune-suppressant drug that also has shown anti-cancer activity and may even slow ageing.

4 Apr 2012

Novel method creates 3-D clusters of pancreatic beta-cells

Three-dimensional clusters of pancreatic beta-cells that live much longer and secrete more insulin than single cells grown in the laboratory are valuable new tools for studying pancreatic diseases such as diabetes and for testing novel therapies.

4 Apr 2012

Brains of people with anorexia and obesity are wired differently

The brains of people with anorexia and obesity are wired differently, according to new research. Neuroscientists for the first time have found that how our brains respond to food differs across a spectrum of eating behaviors - from extreme overeating to food deprivation.

4 Apr 2012

Viewpoints: Shouldering the health costs of the 'irresponsible'; Learning from the parallels between Obamacare and the 'war on terror'

The central idea of the Patient Protection and Affordable Care Act - the formal name of the Obamacare law - emphasized in the hearings is to spread the cost of health care to ever-larger pools of Americans. In particular, to those who pay low health insurance premiums, the young who choose to have no insurance and the healthy.

4 Apr 2012

Researchers figure out how rapamycin causes diabetes

The drug known as rapamycin is widely used by cancer and transplant patients, and there are hints that it might even help us put off old age and live longer. But, it also comes with a downside: rapamycin leads to diabetes in as many as 15 percent of the people who take it.

4 Apr 2012

Topline results from GSK's seven of eight albiglutide Phase 3 studies on type 2 diabetes

Attached is a press release issued earlier this morning by GlaxoSmithKline, announcing that topline results have been received from seven of the eight Harmony Phase 3 studies investigating the use of albiglutide in type 2 diabetes.

4 Apr 2012

Moderate caloric intake may reduce risk of obesity in low-birth weight offspring

Babies who are born small have a tendency to put on weight during childhood and adolescence if allowed free access to calories. However, a new animal model study at UCLA found when small babies were placed on a diet of moderately regulated calories during infancy, the propensity of becoming obese decreased.

3 Apr 2012

Genomic fortune-telling fails to provide informative guidance to most people

With sharp declines in the cost of whole genome sequencing, the day of accurately deciphering disease risk based on an individual's genome may seem at hand. But a study involving data of thousands of identical twins by Johns Hopkins investigators finds that genomic fortune-telling fails to provide informative guidance to most people about their risk for most common diseases, and warns against complacency born of negative genome test results.

3 Apr 2012

Viewpoints: 'Outrageously high fee' for emergency services; Mysterious rise in autism cases

The calculus for medical charges in general is beyond comprehension, with outrageously high fees used as a starting point in a bizarre game of bargaining. Glenn Melnick, who teaches hospital finance at USC, told me it's as crazy as if he asked to buy the TV in my living room, and I gave him a price of $1 million to start the conversation.

3 Apr 2012

NutraGene introduces first ever commercial type 2 diabetes genetic test

With the launch of the country's first ever commercial genetic test for type 2 diabetes, Indians will now have access to clinically relevant and cost effective genetic risk assessment services. NutraGene, a Delhi based genomics company that launched the tests believes that its type 2 diabetes genetic test will provide physicians an effective tool in assessing the risk of diabetes in the Indian population and will help in implementing personalized prevention and management strategies.

3 Apr 2012

New preclinical data on ARIAD's ponatinib and AP26113 study presented at AACR meeting

ARIAD Pharmaceuticals, Inc. today announced the presentation of new preclinical data on its investigational pan-BCR-ABL inhibitor, ponatinib, and its investigational dual EGFR-ALK inhibitor, AP26113, at the American Association for Cancer Research Annual Meeting in Chicago.

3 Apr 2012

AFMR to honor Einstein clinical scientist with Outstanding Investigator Award

Meredith Hawkins, M.D., professor of medicine and director of the Global Diabetes Initiative at Albert Einstein College of Medicine of Yeshiva University, will receive the American Federation for Medical Research's (AFMR) highest honor for medical research, the Outstanding Investigator Award.

3 Apr 2012

Regular walking regimen can benefit cancer survivors

Researchers have affirmed that pancreatic cancer patients can literally take a step-by-step approach to combat fatigue. A study published in the April issue of the Journal of the American College of Surgeons reports that patients who underwent an operation as part of their cancer treatment and then started a regular walking regimen experienced less fatigue than cancer survivors who did not do the walking program.

2 Apr 2012

Rare T follicular helper cells essential for developing antibody responses to infectious agents

The characterisation of a rare immune cell's involvement in antibody production and ability to 'remember' infectious agents could help to improve vaccination and lead to new treatments for immune disorders, say researchers from the Walter and Eliza Hall Institute.

2 Apr 2012

Clinical data for cabozantinib to be presented at ASCO annual meeting

Exelixis, Inc. announced today that its lead compound, cabozantinib, will be the subject of nine separate data presentations at the upcoming Annual Meeting of the American Society of Clinical Oncology.

2 Apr 2012

Twins and mothers with poor nutrition more likely to develop obesity, type 2 diabetes

If you're expecting, this might make you feel a little better about reaching for that pint of ice cream: New research published online in the FASEB Journal suggests that twins, and babies of mothers who diet around the time of conception and in early pregnancy, may have an increased risk of obesity and type 2 diabetes throughout their lives.

2 Apr 2012

Combination of Avastin and Metformin may effectively reduce melanoma growth

COMBINING the experimental drug Avastin (bevacizumab) with the diabetes drug Metformin almost doubles its ability to reduce skin cancer growth, according to a study in Cancer Discovery.

2 Apr 2012

MEK1 mutation does not necessarily make BRAF mutant melanomas resistant to inhibitors

A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true.

2 Apr 2012

Metformin prevents primary liver cancer in animal models

Metformin, a drug widely used to treat Type II diabetes, may help to prevent primary liver cancer, researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center report in the April 2012 issue of Cancer Prevention Research.

2 Apr 2012

Combination of cixutumumab and temsirolimus shrinks tumors in patients with Ewing's sarcoma

A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2012.

2 Apr 2012

Endocrinology News and Research

Latest Endocrinology News and Research

Scientists discover why rapamycin causes diabetic-like symptoms in patients

Novel method creates 3-D clusters of pancreatic beta-cells

Brains of people with anorexia and obesity are wired differently

Viewpoints: Shouldering the health costs of the 'irresponsible'; Learning from the parallels between Obamacare and the 'war on terror'

Researchers figure out how rapamycin causes diabetes

Topline results from GSK's seven of eight albiglutide Phase 3 studies on type 2 diabetes

Moderate caloric intake may reduce risk of obesity in low-birth weight offspring

Genomic fortune-telling fails to provide informative guidance to most people

Viewpoints: 'Outrageously high fee' for emergency services; Mysterious rise in autism cases

NutraGene introduces first ever commercial type 2 diabetes genetic test

New preclinical data on ARIAD's ponatinib and AP26113 study presented at AACR meeting

AFMR to honor Einstein clinical scientist with Outstanding Investigator Award

Regular walking regimen can benefit cancer survivors

Rare T follicular helper cells essential for developing antibody responses to infectious agents

Clinical data for cabozantinib to be presented at ASCO annual meeting

Twins and mothers with poor nutrition more likely to develop obesity, type 2 diabetes

Combination of Avastin and Metformin may effectively reduce melanoma growth

MEK1 mutation does not necessarily make BRAF mutant melanomas resistant to inhibitors

Metformin prevents primary liver cancer in animal models

Combination of cixutumumab and temsirolimus shrinks tumors in patients with Ewing's sarcoma

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Endocrinology News and Research

Latest Endocrinology News and Research

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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