Endocrinology News and Research

Latest Endocrinology News and Research

First-ever comprehensive study of species origins of nature-derived drugs

In a first-ever comprehensive study of the species origins of nature-derived drugs, it is shown that drug-producing species are concentrated and clustered in a limited number of families, refuting the conventional view that as every nature species produces biologically active molecules, one can find drugs from almost any major block of species groups if one looks for them hard enough.

8 Sep 2011

FDA to review bone drugs; CDC reports parasite may be a risk to blood supply

Two advisory panels of the Food and Drug Administration will consider on Friday whether to recommend requiring women who use popular bone drugs like Fosamax to take "drug holidays" because of rising concerns about rare side effects with long-term use, according to people involved in the review.

7 Sep 2011

Loss of estrogen receptor alpha protein may lead to metabolic syndrome

UCLA researchers demonstrated that loss of a key protein that regulates estrogen and immune activity in the body could lead to aspects of metabolic syndrome, a combination of conditions that can cause Type 2 diabetes, atherosclerosis and cancer. Called estrogen receptor alpha, this protein is critical in regulating immune system activity such as helping cells suppress inflammation and gobble-up debris.

7 Sep 2011

Scientists discover 29 new genetic variants linked with MS

Multiple sclerosis is primarily an immunological disease. Scientists at Charité - Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine (MDC) have in succeeded, in collaboration with 23 research teams from 15 different countries, in discovering a total of 29 new genetic variants that are involved in the genesis of multiple sclerosis (MS), an inflammatory disease of the nervous system.

7 Sep 2011

Individuals with excess BMI more likely to develop type 2 diabetes

Obesity is a known risk factor for developing type 2 diabetes. But it hasn't been clear whether the "dose" of obesity—how much excess weight a person has, and for how long—affects the risk of diabetes.

7 Sep 2011

Biomaterials may heal chronic diabetic wounds

Biomaterials may prove key to healing chronic wounds in Diabetic patients, delegates will hear today at the 24th European Conference on Biomaterials. Over 950 delegates are at the event in Dublin, which is jointly hosted by NUI Galway's Network of Excellence for Functional Biomaterials and the University of Ulster, Jordanstown.

7 Sep 2011

Combination of blood tests and ROMA algorithm receives FDA clearance to treat ovarian cancer

Approval last week by U.S. Food and Drug Administration (FDA) clears the path for nationwide use of tools that show the greatest specificity in estimating the risk of ovarian cancer in women with a pelvic mass.

7 Sep 2011

Pancreatic mesenchyme plays central role in the formation of mature beta cells

A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body's insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes.

7 Sep 2011

Scientists uncover new ways to stimulate pancreatic beta cell growth

One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates it.

7 Sep 2011

Researchers investigate special diets that could help youngsters keep the weight off

A shocking 17 per cent of boys and 15 per cent of girls aged two to 15 years are obese in the UK, putting them at risk of serious, long-term health problems. Now a team of Aberdeen researchers are investigating special diets which could help youngsters keep the weight off, thanks to a grant from children's charity Action Medical Research.

7 Sep 2011

Duodenal switch may lead to more weight loss but more complications: Study

A less usual and common type of obesity surgery may spur more weight loss than its far more popular cousin, gastric bypass - but at the price of greater long-term risks, researchers reported.

6 Sep 2011

Diabetes prevention in five steps: Study

According to a new study meeting just one of five key health goals reduces the odds of developing diabetes in middle age by roughly one-third. The report adds that the more goals are met the lower the risk falls, even if there is a family history of diabetes.

6 Sep 2011

Discovery of a key protein’s role in cell clearance could impact future treatments of autoimmune diseases, obesity and atherosclerosis

The healthy human body is extremely efficient at cleaning house. Every day, we purge 100 to 200 billion dead or dying cells – a process called cell clearance, which is fundamental in our ability to maintain a healthy physiological balance and prevent a number of chronic diseases. Professional cleaning cells, called phagocytes, are responsible for ridding the body of dead, or ‘apoptotic,’ cells.

6 Sep 2011