Endocrinology News and Research

Latest Endocrinology News and Research

Gene variant linked to infertility in women

A variation in a gene involved in regulating cholesterol in the bloodstream also appears to affect progesterone production in women, making it a likely culprit in a substantial number of cases of their infertility, a new study from Johns Hopkins researchers suggests.

16 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

Amylin files lawsuit against Eli Lilly for improper commercialization of exenatide

Amylin Pharmaceuticals, Inc. today announced that it has filed a lawsuit against Eli Lilly and Company in the United States District Court for the Southern District of California, alleging that Lilly is engaging in anticompetitive activity and breaching its strategic alliance agreements with Amylin to maximize commercialization of exenatide.

16 May 2011

Study reveals role of KLF14 regulatory gene in type 2 diabetes

A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour of other genes found within fat in the body.

16 May 2011

Study reveals crucial role of histone deacetylases in type 2 diabetes

A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease.

16 May 2011

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.

16 May 2011

Study associates VDR gene variant with onset of chronic obstructive pulmonary disease in men

Researchers have linked a variant in the vitamin D receptor gene (VDR) with the onset of chronic obstructive pulmonary disease (COPD) in Caucasian men. The study population consisted of participants in the Veterans Administration Normative Aging Study, a multidisciplinary study of aging that began in 1963.

16 May 2011

China's SFDA approves TPI anti-diabetic drug Gliclazide

Tianyin Pharmaceutical Co., Inc., a pharmaceutical company that specializes in patented biopharmaceutical medicine, modernized traditional Chinese medicine, branded generics and other pharmaceuticals today announced that TPI has received the China's SFDA's approval for its anti-diabetic drug Gliclazide Tablets.

13 May 2011

Majority of high-risk heart disease patients have poor adherence to statin treatment

A new study from North Carolina State University shows that the vast majority of patients at high risk for heart disease or stroke do a poor job of taking statins as prescribed. That's especially unfortunate, because the same study shows that taking statins can significantly increase the quality and length of those patients' lives.

13 May 2011

Medtronic to present new clinical results on innovative medical devices at EuroPCR

New clinical data on a range of innovative medical devices from Medtronic, Inc., to treat cardiac and vascular diseases - from severe aortic stenosis and uncontrolled hypertension, to coronary and peripheral artery disease - will be presented next week at EuroPCR. Many of the presentations will be featured during late-breaking sessions at this large international interventional cardiology meeting, which takes place in Paris from May 17-20.

From Medtronic 12 May 2011

Reprogrammed herpes virus can improve early cancer diagnosis

Scientists have used a genetically re-engineered herpes virus that selectively hunts down and infects cancerous tumors and then delivers genetic material that prompts cancers to secrete a biomarker and reveal their presence.

12 May 2011

Researcher finds ultrasound as effective as CT scans for head and neck diagnoses

For diagnosing head and neck ailments, tests that use radiation are always less desirable than those that don't. Otolaryngologists have a wide range of techniques available to them, including CT or "CAT" scans, MRI and ultrasound.

12 May 2011

Scientists to discuss latest autism research findings at IMFAR meeting

The 10th Annual International Meeting for Autism Research will host more than 1900 researchers, delegates, autism specialists, and students in the world's largest gathering of researchers and clinicians devoted to a better understanding of autism. The meeting will be held at the Manchester Grand Hyatt from May 12-14, 2011.

12 May 2011

Santaris Pharma advances SPC4955 into Phase 1 trial for high cholesterol treatment

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, today announced that it has advanced a second drug from its cardiometabolic program, SPC4955 into Phase 1 clinical trials, for the treatment of high cholesterol.

11 May 2011

Two new policy briefs on California health reform law

According to two new policy briefs from the UCLA Center for Health Policy Research, the majority of state residents likely to be eligible for federally mandated health insurance coverage initiatives in California in 2014 are also those who may be least likely to excessively use costly health services: men, singles and those of working age.

11 May 2011

Amylin, JDRF collaborate to investigate combination therapy for type 1 diabetes treatment

The Juvenile Diabetes Research Foundation and Amylin Pharmaceuticals, Inc. announced today that they have entered into a research collaboration agreement to provide financial support for a series of clinical studies to investigate the feasibility of mixing pramlintide, an analog of the human hormone amylin, with insulin to treat type 1 diabetes.

11 May 2011

Common tiny tropical fish plays a key role in new model for Cushing disease

A common, tiny tropical fish plays a key role in a new model for Cushing disease, giving researchers a powerful tool to conduct extensive searches for effective treatments for this serious hormonal disorder, testing up to 300 drugs weekly.

11 May 2011

Study evaluates link between thyroid autoantibodies, miscarriage and preterm birth

GW Researcher Dr. Alex Stagnaro-Green, and colleagues, have contributed an editorial featured in the May 14 issue of the British Medical Journal reviewing a study that evaluated the relationship between thyroid autoantibodies and both miscarriage and preterm birth.

11 May 2011

Shanghai Zhabei Health Bureau, CWRU sign 10-year research deal to study Chinese lifestyle

Case Western Reserve University School of Medicine has signed an unprecedented 10-year research agreement with the Shanghai Zhabei District Health Bureau to study how an increasingly westernized diet and a less active lifestyle are affecting the health of China's residents.

11 May 2011

Depressed patients with chronic illnesses less likely to adhere to medications

People who are depressed are less likely to adhere to medications for their chronic health problems than patients who are not depressed, putting them at increased risk of poor health, according to a new RAND Corporation study.

11 May 2011

Endocrinology News and Research

Latest Endocrinology News and Research

Gene variant linked to infertility in women

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Amylin files lawsuit against Eli Lilly for improper commercialization of exenatide

Study reveals role of KLF14 regulatory gene in type 2 diabetes

Study reveals crucial role of histone deacetylases in type 2 diabetes

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Study associates VDR gene variant with onset of chronic obstructive pulmonary disease in men

China's SFDA approves TPI anti-diabetic drug Gliclazide

Majority of high-risk heart disease patients have poor adherence to statin treatment

Medtronic to present new clinical results on innovative medical devices at EuroPCR

Reprogrammed herpes virus can improve early cancer diagnosis

Researcher finds ultrasound as effective as CT scans for head and neck diagnoses

Scientists to discuss latest autism research findings at IMFAR meeting

Santaris Pharma advances SPC4955 into Phase 1 trial for high cholesterol treatment

Two new policy briefs on California health reform law

Amylin, JDRF collaborate to investigate combination therapy for type 1 diabetes treatment

Common tiny tropical fish plays a key role in new model for Cushing disease

Study evaluates link between thyroid autoantibodies, miscarriage and preterm birth

Shanghai Zhabei Health Bureau, CWRU sign 10-year research deal to study Chinese lifestyle

Depressed patients with chronic illnesses less likely to adhere to medications

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Endocrinology News and Research

Latest Endocrinology News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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