Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Celiac disease people may have near two-fold increased risk of coronary artery disease

People with celiac disease may have a near two-fold increased risk of coronary artery disease compared with the general population, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

Actavis gets favorable ruling in patent suit against generic Lialda

Actavis plc today confirmed that the United States Court of Appeals for the Federal Circuit has reversed a lower court ruling that Actavis' generic version of Shire's Lialda (mesalamine extended-release tablets) infringes United States Patent No. 6,773,720 (the '720 Patent).

29 Mar 2014

Infants who experience ALTEs have abnormal regulation of esophageal function

About 1 percent of all emergency room visits are prompted by near-death experiences in infants, such as extended periods without breathing or sudden changes in skin pallor or muscle tone. What causes these frightening experiences is often unknown, but the result can be long hospital stays and neurological impairment.

29 Mar 2014

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Infectious disease specialists at the Johns Hopkins Children's Center have identified a protein that regulates the body's immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune systems.

27 Mar 2014

Ulcerative colitis control: an interview with Dr Paul Robinson, Medical Director, MSD UK

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD), which means there is chronic inflammation and ulceration in the lining of the digestive tract, usually in the large intestine.

26 Mar 2014

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

Is irritable bowel syndrome (IBS) caused by genetics, diet, past trauma, anxiety? All are thought to play a role, but now, for the first time, researchers have reported a defined genetic defect that causes a subset of IBS. The research was published in the journal Gastroenterology.

21 Mar 2014

Concordia Healthcare enters into definitive agreement to acquire Donnatal

Concordia Healthcare Corp., announced today that it has entered into a definitive agreement to acquire Donnatal®, an adjunctive therapy in the treatment of irritable bowel syndrome ("IBS") and acute enterocolitis, from a privately held specialty pharmaceutical company carrying on business as Revive Pharmaceuticals ("Revive Pharmaceuticals").

20 Mar 2014

New stool-based screening test detects 92% of colorectal cancer

A new, non-invasive, stool-based screening test detected 92% of colorectal cancer (CRC), according to a multicenter trial published online today in the New England Journal of Medicine.

20 Mar 2014

Scientists describe gut bacteria that cause sepsis in preterm infants

Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream.

19 Mar 2014

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Amgen (NASDAQ: AMGN) today announced that the Phase 3 TESLA (Trial Evaluating PCSK9 Antibody in Subjects with LDL Receptor Abnormalities) trial evaluating evolocumab met its primary endpoint of the percent reduction from baseline at week 12 in low-density lipoprotein cholesterol (LDL-C).

19 Mar 2014

Biologists discover WBC moves to inflamed sites by walking in a stepwise manner

A team of biologists and engineers at the University of California, San Diego has discovered that white blood cells, which repair damaged tissue as part of the body's immune response, move to inflamed sites by walking in a stepwise manner.

19 Mar 2014

Ironwood Pharmaceuticals starts Phase IIa clinical study of IW-3718 for gastroesophageal reflux disease

Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) announced today that dosing has begun in its Phase IIa clinical study of its investigational compound IW-3718 in patients suffering from gastroesophageal reflux disease (GERD) who have not responded adequately to treatment with a proton pump inhibitor (PPI). Data are expected in the first half of 2015.

18 Mar 2014

Microbial DNA may be involved in the development of autoimmune processes, shows study

The interactions of the gut microbiota in children with typical diabetes autoantibodies differ from that in healthy children. The fact that these differences already exist before antibodies are detectable in the blood adds to the growing evidence that microbial DNA, the so-called microbiome, may be involved in the development of autoimmune processes.

13 Mar 2014

Two definitions of CMI symptoms should guide research and treatment of Gulf War veterans

Two existing definitions of chronic multisymptom illness (CMI) -- one by the Centers for Disease Control and Prevention and another from a study of Kansas Gulf War veterans -- should be used by the U.S. Department of Veterans Affairs to guide research and treatment of Gulf War veterans, says a new report from the Institute of Medicine.

13 Mar 2014

Researchers seek 400 treatment-naïve colon participants to measure non-invasive blood test

Investigators with Baylor Research Institute, a research arm of Baylor Scott & White Health, have opened participation for a new clinical trial that could determine whether a certain blood test can detect colon cancer before it even develops.

12 Mar 2014

Scientist receives AGA-GCF Research Scholar Award for research in gastric, esophageal cancer

The American Gastroenterological Association (AGA) Research Foundation and the Gastric Cancer Foundation (GCF) are pleased to announce that the first AGA-Gastric Cancer Foundation Research Scholar Award in Gastric and Esophageal Cancer will support Mohamed El-Zaatari, PhD, from University of Michigan, as he conducts research into the role of myeloid cells in the transition from chronic inflammation to gastric pre-neoplasia.

12 Mar 2014

Clinipace Worldwide closes merger with Choice Pharma

Clinipace Worldwide, a global digital contract research organization (dCRO), announced today the closing of its merger with Choice Pharma, a Pan-Asian contract research organization. Bringing these organizations together strengthens Clinipace Worldwide's operational and therapeutic expertise in Asia, a region in high demand by Clinipace's clients.

11 Mar 2014

SCCA experts develop helpful tool to simplify colon cancer prevention, screening guidelines

Colon cancer will take more than 50,000 American lives in 2014 making it the second leading cause of cancer-related deaths, according to the American Cancer Society.

11 Mar 2014

Findings suggest that IBS is linked to detectable gut microbiota alterations

Irritable bowel syndrome (IBS) belongs to the most widespread diseases in Western countries, causing up to sixty per cent of the workload of gastrointestinal physicians. One of the most frequent symptoms of IBS is bloating, which reduces quality of life considerably as patients perceive it as particularly bothersome.

10 Mar 2014

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Researchers have demonstrated that conditioned pain modulation (CPM), a measure of the brain's ability to regulate pain, decreases activity in the human spinal cord as visible via functional magnetic resonance imaging (fMRI).

10 Mar 2014

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Celiac disease people may have near two-fold increased risk of coronary artery disease

Actavis gets favorable ruling in patent suit against generic Lialda

Infants who experience ALTEs have abnormal regulation of esophageal function

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Ulcerative colitis control: an interview with Dr Paul Robinson, Medical Director, MSD UK

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

Concordia Healthcare enters into definitive agreement to acquire Donnatal

New stool-based screening test detects 92% of colorectal cancer

Scientists describe gut bacteria that cause sepsis in preterm infants

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Biologists discover WBC moves to inflamed sites by walking in a stepwise manner

Ironwood Pharmaceuticals starts Phase IIa clinical study of IW-3718 for gastroesophageal reflux disease

Microbial DNA may be involved in the development of autoimmune processes, shows study

Two definitions of CMI symptoms should guide research and treatment of Gulf War veterans

Researchers seek 400 treatment-naïve colon participants to measure non-invasive blood test

Scientist receives AGA-GCF Research Scholar Award for research in gastric, esophageal cancer

Clinipace Worldwide closes merger with Choice Pharma

SCCA experts develop helpful tool to simplify colon cancer prevention, screening guidelines

Findings suggest that IBS is linked to detectable gut microbiota alterations

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Your full guide to the gut microbiome eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Your full guide to the gut microbiome eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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