Gene News and Research

Latest Gene News and Research

Breakthrough research unveils retroelement-based aging biomarkers

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

19 Aug 2024

Researchers identify possible candidates for multipotent stem cells in the sea anemone

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

19 Aug 2024

New Springer textbook provides a comprehensive overview of aging science

A new textbook provides an overview on the present understanding of aging - from the basic biology of aging to age-related diseases and to the role of lifestyle and the environment.

19 Aug 2024

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

The long-term subjective cognitive decline risk associated with Herpes zoster infections.

19 Aug 2024

ASTN2 gene knockout in mice reveals key autism-related behaviors

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, social communication, hyperactivity, and repetitive movements.

16 Aug 2024

New study reveals overlap between metabolic and immune disorders

Inherited diseases of metabolism and immunity have more in common than previously recognized, according to a new study published in the journal Science Immunology.

16 Aug 2024

Study highlights LLPS's influence on signaling pathways and disease progression

This paper, led by Professor Wu (Wenzhou Institute University, Wenzhou Medical University) and Professor Huang (Northeastern University), explores LLPS, a phenomenon closely associated with various diseases, including cancer and neurodegenerative disorders.

16 Aug 2024

Weill Cornell Medicine secures $12.4 million grant for lymphoma research

Weill Cornell Medicine has received a five-year, $12.4 million grant from the National Cancer Institute, part of the National Institutes of Health, for an extensive program of basic and translational research on the biology of diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma.

15 Aug 2024

Groundbreaking study uncovers new genetic variants linked to normal pressure hydrocephalus

A new study by the University of Eastern Finland and partners identified new genetic variants associated with normal pressure hydrocephalus (NPH).

15 Aug 2024

New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

Engineering extracellular vesicles for potential treatment of type 1 diabetes

Within each of us lies an army of cells whose topmost duty is protecting against external pathogens and internal threats such as proliferating cancer cells.

14 Aug 2024

New tool shows promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy

A pilot study using a new screening tool shows promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy (DMD) and improving quality of life for patients and their families.

14 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

Study reveals how chromatin structure influences social behavior in dogs

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior.

14 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future influenza vaccination strategies.

13 Aug 2024

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden's Uppsala University, has published the largest multi-omics study of colorectal cancer (CRC) to date.

13 Aug 2024

Mrc1 protein identified as key to maintaining cell identity during division

In a major scientific breakthrough, researchers have found that a protein called Mrc1 plays a crucial role in ensuring that cells keep their identity as they divide and grow.

13 Aug 2024

Decline in psychological wellbeing may signal early mild cognitive impairment

Feeling that your life lacks purpose and that there are few opportunities for personal growth in older age may precede the development of mild cognitive impairment (MCI), a frequent precursor of dementia, suggests research published online in the Journal of Neurology Neurosurgery & Psychiatry.

13 Aug 2024

Gene News and Research

Latest Gene News and Research

Breakthrough research unveils retroelement-based aging biomarkers

Researchers identify possible candidates for multipotent stem cells in the sea anemone

New Springer textbook provides a comprehensive overview of aging science

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

ASTN2 gene knockout in mice reveals key autism-related behaviors

New study reveals overlap between metabolic and immune disorders

Study highlights LLPS's influence on signaling pathways and disease progression

Weill Cornell Medicine secures $12.4 million grant for lymphoma research

Groundbreaking study uncovers new genetic variants linked to normal pressure hydrocephalus

New research gives unprecedented view of colorectal cancer genetic makeup

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Engineering extracellular vesicles for potential treatment of type 1 diabetes

New tool shows promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy

Ketogenic diet can boost efficacy of pancreatic cancer therapy

Study reveals how chromatin structure influences social behavior in dogs

New targets for improved cancer immunotherapy

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Largest multi-omics study identifies new genetic landscapes in colorectal cancer

Mrc1 protein identified as key to maintaining cell identity during division

Decline in psychological wellbeing may signal early mild cognitive impairment

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich