Gene News and Research

Latest Gene News and Research

Bazedoxifene used for treating osteoporosis stops growth of breast cancer cells

A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.

17 Jun 2013

RetroNectin reagent now available for gene therapy clinical research

In an effort to aid progress in gene therapy clinical research, representatives of Clontech laboratories, Inc. and its parent company Takara Bio Inc. announce the availability of clinical grade RetroNectin reagent for direct supply to biomedical researchers.

17 Jun 2013

Researchers produce first genome-wide investigation of cap-independent translation

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates-a process commonly known as translation. While the general mechanism of translation has been understood for some time, protein synthesis can initiate by more than one mechanism. One of the least well understood mechanisms is known as cap-independent translation.

17 Jun 2013

European Commission amends marketing authorisation for Celgene's REVLIMID

Celgene International Sàrl was today notified that the European Commission has amended the marketing authorisation for REVLIMID. This decision means that REVLIMID is now approved to treat patients with transfusion-dependent anaemia due to low or intermediate-1 risk myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate.

17 Jun 2013

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia.

17 Jun 2013

Researchers identify genetic mutation responsible for MDP Syndrome

National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin - yet has type 2 diabetes - and suffered hearing loss as a child. Now, thanks to advances in genome sequencing, an international research team led by the University of Exeter Medical School has identified Tom's condition and pinpointed the single genetic mutation that causes it.

17 Jun 2013

Ibrutinib monotherapy shows efficacy in patients with MCL or DLBCL

Pharmacyclics, Inc. today announced the results of two separate Phase 2 studies suggesting that ibrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, showed efficacy when used as a monotherapy in patients with relapsed/refractory mantle cell lymphoma or diffuse large B-cell lymphoma.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

Pathway Genomics led the evening news Friday with an announcement that it could begin offering affordable access to genetic testing for the BRCA gene linked to breast and ovarian cancers in the wake of a Supreme Court ruling that eliminated another company's monopoly on the test.

15 Jun 2013

Celgene International Sàr presents PALACE 3 phase III results of apremilast in psoriatic arthritis at EULAR

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ: CELG), today announced results from PALACE 3, the Company's third phase III study in psoriatic arthritis (PsA), at EULAR, the European Congress of Rheumatology annual meeting in Madrid, Spain.

15 Jun 2013

In unanimous decision, Supreme Court justices rule genes can't be patented

The decision was applauded by many researchers and drew speculation that it could likely boost patient care. Meanwhile, the stock of Myriad Genetics tumbled after the court's finding invalidated the company's hold on testing for two breast cancer genes.

15 Jun 2013

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor.

15 Jun 2013

Supreme Court DNA ruling leaves questions unanswered

Editorial boards weigh in on what Thursday's Supreme Court ruling means for medical research and for the medical industry.

15 Jun 2013

Gene variants may predict which women are most likely to benefit from breast cancer therapy

In women at high risk for breast cancer, a long-term drug treatment can cut the risk of developing the disease in half. Researchers supported by the National Institutes of Health have now identified two gene variants that may predict which women are most likely to benefit from this therapy—and which should avoid it.

14 Jun 2013

First Edition: June 14, 2013

Today's headlines includes reports about how, after months of battle, Arizona lawmakers endorsed a Medicaid expansion plan backed by Gov. Jan Brewer.

14 Jun 2013

Pew funds early-career scientists researching the basis of perplexing health problems

Twenty-two of the nation's most enterprising researchers were named Pew Scholars in the Biomedical Sciences by The Pew Charitable Trusts today. The scholarships provide flexible funding to early-career scientists researching the basis of perplexing health problems such as diabetes, autism, Parkinson's disease, and cancer.

14 Jun 2013

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Today, researchers at Albert Einstein College of Medicine of Yeshiva University convened a one-day conference on Jewish genetics designed to encourage collaboration and advance the field of research.

14 Jun 2013

Supreme Court invalidates patents held by Myriad Genetics

The College of American Pathologists applauds today's unanimous Supreme Court decision invalidating the patents held by Myriad Genetics on the BRCA1 and BRCA2 genes. It is a victory for patients and for science.

14 Jun 2013

Celgene reports results from placebo-controlled phase II trial in patients with Behçet's disease

Celgene International Sàrl, a subsidiary of Celgene Corporation today presented results from a randomized, placebo-controlled phase II trial in patients with Behçet's disease at EULAR, the European Congress of Rheumatology annual meeting in Madrid.

14 Jun 2013

Genetic variations may help predict breast cancer risk in women who receive preventive therapy

Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery.

14 Jun 2013

Gene News and Research

Latest Gene News and Research

Bazedoxifene used for treating osteoporosis stops growth of breast cancer cells

RetroNectin reagent now available for gene therapy clinical research

Researchers produce first genome-wide investigation of cap-independent translation

European Commission amends marketing authorisation for Celgene's REVLIMID

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers identify genetic mutation responsible for MDP Syndrome

Ibrutinib monotherapy shows efficacy in patients with MCL or DLBCL

New research reports that UnaG protein could lead to new liver test

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

Celgene International Sàr presents PALACE 3 phase III results of apremilast in psoriatic arthritis at EULAR

In unanimous decision, Supreme Court justices rule genes can't be patented

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Supreme Court DNA ruling leaves questions unanswered

Gene variants may predict which women are most likely to benefit from breast cancer therapy

First Edition: June 14, 2013

Pew funds early-career scientists researching the basis of perplexing health problems

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Supreme Court invalidates patents held by Myriad Genetics

Celgene reports results from placebo-controlled phase II trial in patients with Behçet's disease

Genetic variations may help predict breast cancer risk in women who receive preventive therapy

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