Gene News and Research

Latest Gene News and Research

Scientists unlock secrets of gene regulatory networks

A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences ( PNAS ).

3 Feb 2009

Heart drug improve learning and memory in middle-aged rats

A team of Arizona psychologists, geneticists and neuroscientists has reported that a safe and effective drug used to treat vascular problems in the brain has improved spatial learning and working memory in middle-aged rats.

2 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Quantum dot hazards

Quantum dots have the potential to bring many good things into the world: efficient solar power, targeted gene and drug delivery, solid-state lighting and advances in biomedical imaging among them.

2 Feb 2009

Rhythm abnormality of unknown origin strongly predicts sudden death risk in heart disease patients

Researchers conducting a large, ongoing study to improve detection and prevention of sudden cardiac death were surprised to discover that a specific heart rhythm abnormality – idiopathic QT interval prolongation – increased risk five-fold among patients with coronary artery disease.

2 Feb 2009

Gene expression signature associated with survival in advanced ovarian cancer

A new study published this week in the open-access journal PLoS Medicine identifies molecular pathways associated with outcomes in ovarian cancer.

2 Feb 2009

Genetic change prevents cell death in mouse model of Parkinson's disease

By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's disease.

2 Feb 2009

Discovery fleshes out metabolism of key environmental and energy bacteria

An international collaboration of researchers has discovered a new enzyme in a species of bacteria with potential environmental cleanup and energy roles.

2 Feb 2009

New genetic clues on molecular evolution of Q fever pathogen

Scientists from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center, and the Virginia Bioinformatics Institute at Virginia Tech have uncovered genetic clues about why some strains of the pathogen Coxiella burnetii are more virulent than others.

2 Feb 2009

Shortened gene region linked to breast cancer

Reza Zarnegar and colleagues, at the University of Pittsburgh, Pittsburgh, have determined that genetic variation in a piece of DNA that regulates activity of the HGF gene might be a useful marker to identify individuals with an increased risk of developing breast cancer.

2 Feb 2009

Single gene lets bacteria jump from host to host

All life - plants, animals, people - depends on peaceful coexistence with a swarm of microbial life that performs vital services from helping to convert food to energy to protection from disease.

2 Feb 2009

Link found between Parkinson's disease genes and manganese poisoning

A connection between genetic and environmental causes of Parkinson's disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.

2 Feb 2009

New CDC study assesses impact of genetic testing on health outcomes

Some genomic tests developed to personalize medical decisions about cancer care are beneficial, while for others the evidence is uncertain and reliance on the test might even lead to poorer medical management of cancer in some cases, according new recommendation statements from an expert panel.

2 Feb 2009

Research finds more than 100 gene variations linked with response to leukemia treatment

Scientists from St. Jude Children's Research Hospital and the Children's Oncology Group (COG) have discovered in children with acute lymphoblastic leukemia (ALL) scores of inherited genetic variations that clinicians might be able to use as guideposts for designing more effective chemotherapy for this cancer.

29 Jan 2009

Researchers discover link between brain iron levels and serotonin

Vanderbilt University Medical Center investigators have found a surprising link between brain iron levels and serotonin, a neurotransmitter involved in neuropsychiatric conditions ranging from autism to major depression.

29 Jan 2009

New insights into a avian pathogenic E. coli and its risks to human health

Biodesign Institute at Arizona State University associate research scientist Melha Mellata, a member of professor Roy Curtiss' team, is leading a USDA funded project to develop a vaccine against a leading poultry disease called avian pathogenic E. coli (APEC).

29 Jan 2009

New bone cement may prevent amputations

Old technologies, bone cement and a well known antibiotic, may effectively fight an emerging infection in soldiers with compound bone fractures, according to a study published online in the Journal of Orthopedic Research.

29 Jan 2009

SAFC Pharma augments assay development capabilities

SAFC Pharma, a business segment of SAFC, a member of the Sigma-Aldrich group, today announced that it has commenced operations at its 7,000 sq. ft. state-of-the-art laboratory complex in Carlsbad, CA.

29 Jan 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

New understanding of genetic basis of psoriasis

Two international teams of researchers have made significant gains in understanding the genetic basis of psoriasis, a chronic skin condition that can be debilitating in some patients.

27 Jan 2009