Gene News and Research

Latest Gene News and Research

Preclinical efficacy data of Sangamo's ZFN based human stem cell therapy for HIV published

Sangamo BioSciences, Inc. announced the publication of data demonstrating the preclinical efficacy of a human stem cell therapy for human immunodeficiency virus (HIV) based on its proprietary zinc finger DNA-binding protein nuclease (ZFN) technology.

6 Jul 2010

Depression increases risk of developing dementia later in life

A new study shows that having depression may nearly double your risk of developing dementia later in life. The research will be published in the July 6, 2010, issue of Neurology-, the medical journal of the American Academy of Neurology.

6 Jul 2010

Novel therapy slows tumor growth in 85% of advanced breast cancer patients: Study

A novel therapy designed to attack tumors in patients with a genetic mutation in either BRCA1 or BRCA2, slowed tumor growth in 85 percent of advanced breast cancer patients treated in a small study, researchers report in the July 6 issue of The Lancet.

6 Jul 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Mount Sinai Hospital researchers including Drs. Andras Nagy and Jeff Wrana have discovered new insights into the genesis of stem cells, which will improve the efficiency of stem cell creation for use in tissue regeneration and in the development of new drugs.

3 Jul 2010

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

A new gene that normally protects against ovarian cancer is switched-off in two-thirds of cases of the disease, reveals a study published in the journal Neoplasia today.

3 Jul 2010

First US forum gathers doctors and children who no longer need insulin

Twenty-five families who have overcome diabetes caused by a defect in a single gene will gather at "Celebrating the Miracles," a University of Chicago symposium for patients, parents and physicians. The first Monogenic Diabetes Forum is designed to review scientific studies, celebrate treatment successes, stress the importance of a genetic diagnosis for children diagnosed before age one, and exchange tips on how to make the most of a new concept--life without insulin injections.

3 Jul 2010

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

When does a cell decide its particular identity? According to biologists at the California Institute of Technology (Caltech), in the case of T cells-immune system cells that help destroy invading pathogens-the answer is when the cells begin expressing a particular gene called Bcl11b.

3 Jul 2010

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

Utilizing Fluidigm Corporation's Dynamic Array™ and Digital Array™ integrated fluidic circuits (IFCs), Stanford University researchers to have discovered a much larger spectrum of differences between individual cells than has previously been demonstrated. Among these differences are the communication capabilities that emerge from the interactions of genetic circuitry that mediates cell-to-cell communication.

2 Jul 2010

ISHLT issues first international consensus formulation of standardized nomenclature for CAV

Cardiac allograft vasculopathy (CAV), the major limitation to long term survival after heart transplantation, occurs when blood vessels in a transplanted heart progressively narrow and lead to dysfunction of the heart muscle or sudden death. Ascertaining benefit from appropriate treatment for this condition has been hampered in part because of the lack of a standard nomenclature.

2 Jul 2010

Virus related to hepatitis C discovered in Asian bats

Viral hepatitis affects more than 500 million people worldwide and is a cause of liver failure and liver cancer. While vaccines are available for hepatitis A and B, this is not the case for hepatitis C, which affects as much as two percent of the population in the U.S. Scientists today are reporting discovery of a virus related to hepatitis C in Asian bats, which may provide insights into the origins of the hepatitis C virus and into the mechanisms by which infectious diseases move from other species to humans.

2 Jul 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Researchers identify gene abnormality for most common congenital birth defect, clubfoot

Although clubfoot is one of the most common congenital birth defects, few genetic causes have been found. Now, researchers at Washington University School of Medicine in St. Louis have found what they believe to be the most common cause of inherited clubfoot yet discovered.

2 Jul 2010

Cancer stem cells may vary from tumor to tumor, say researchers

Cancer stem cells have enticed scientists because of the potential to provide more durable and widespread cancer cures by identifying and targeting the tumor's most voracious cells.

2 Jul 2010

Research shows promising targeted therapies for type 2 diabetes patients

Named for the furballs whose astonishing fecundity made them stars in early Star Trek episodes, the tribbles protein, first identified in fruit flies, aids in regulating many cell processes in humans. Joslin Diabetes Center researchers now have identified mechanisms triggered by a variant of the tribbles gene that cause trouble in insulin-producing pancreatic beta cells—and that offer a promising target for therapies for people with type 2 diabetes, even if they don't carry that gene variant.

2 Jul 2010

Scientists explain mechanism behind acute myeloid leukemia

New research by scientists at Cold Spring Harbor Laboratory (CSHL) has illuminated in fine detail one of the genetic paths that leads to a particularly aggressive form of leukemia.

2 Jul 2010

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

SAIC-Frederick, Inc. and Fluidigm Corporation are collaborating to decode the entire genome of the Epstein-Barr virus (EBV) using technology that can speed up research on the genetic basis of cancer and other diseases.

1 Jul 2010

Babies born after IVM fertility treatment more likely to be born larger than normal

A review of studies of babies born after in vitro maturation (IVM) fertility treatment has suggested that they are more likely to be born larger than normal and to have more difficult births requiring more obstetric interventions such as caesareans.

1 Jul 2010

Research findings suggest new treatment approach to improve corneal transplants

Although it is already one of medicine's most successful transplant procedures, doctors continue to seek ways to improve corneal transplants. Now, for the first time, a team of German and British researchers have confirmed that failure and rejection of transplanted corneas are more likely in patients whose eyes exhibit abnormal vessel growth, called corneal neovascularization, prior to surgery.

1 Jul 2010

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene "program" that stimulates growth of the stem cells and may even play a role in cancer, said a group of researchers led by Baylor College of Medicine in a current report in the journal Genes and Development.

1 Jul 2010

Mutations in Siglec-8 gene may play role in asthma: Research

A gene that encodes a protein responsible for determining whether certain immune cells live or die shows subtle differences in some people with asthma, a team led by Johns Hopkins researchers reports in the June European Journal of Human Genetics.

1 Jul 2010

Gene News and Research

Latest Gene News and Research

Preclinical efficacy data of Sangamo's ZFN based human stem cell therapy for HIV published

Depression increases risk of developing dementia later in life

Novel therapy slows tumor growth in 85% of advanced breast cancer patients: Study

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

First US forum gathers doctors and children who no longer need insulin

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

ISHLT issues first international consensus formulation of standardized nomenclature for CAV

Virus related to hepatitis C discovered in Asian bats

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Researchers identify gene abnormality for most common congenital birth defect, clubfoot

Cancer stem cells may vary from tumor to tumor, say researchers

Research shows promising targeted therapies for type 2 diabetes patients

Scientists explain mechanism behind acute myeloid leukemia

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

Babies born after IVM fertility treatment more likely to be born larger than normal

Research findings suggest new treatment approach to improve corneal transplants

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Mutations in Siglec-8 gene may play role in asthma: Research

eBook: Using iPSCs models for human disease research and drug discovery eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR