Gene News and Research

Latest Gene News and Research

COVID-19 may increase risk of pregnancy complications through placental DNA changes

DNA changes consistent with life-threatening pregnancy complications have been found in the placentas of pregnant women infected by COVID-19, according to University of Queensland researchers.

8 Feb 2024

New mouse model illuminates lung cancer's transformation into aggressive variant

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment.

8 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

ANU discovery provides new insight into how the immune system fights malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers.

8 Feb 2024

Study advances search for a blood test to identify disease-associated changes in the brain

Researchers in a Johns Hopkins Children's Center-led study that used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

8 Feb 2024

Parental traits offer new clues to predicting neurodevelopmental disorders in children

Predicting the trajectory of neurodevelopmental and psychiatric disorders like autism or schizophrenia is difficult because they can be influenced by many different genetic and environmental factors.

8 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron.

7 Feb 2024

Immune cell networks key to success of personalized cancer treatment

Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

7 Feb 2024

New study sheds light on sex differences in allergic airway inflammation

Researchers explored how sex hormones and chromosomes influence allergic inflammation and gene expression in four-core genotype (FCG) mice exposed to house dust mites (HDMs).

7 Feb 2024

New link between stress, immune system, and depression discovered

Chronic stress affects the immune system and the brain. UZH researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress.

7 Feb 2024

Researchers uncover how deadly MRSA pneumonia inhibits body's antimicrobial activity

Researchers examined how heparan sulfate (HS) shedding impacts cathelicidin efficacy in Methicillin-Resistant Staphylococcus aureus (MRSA) pneumonia.

7 Feb 2024

Researchers develop new approach to improve the accuracy of RNA sequencing

A team at NDORMS, University of Oxford has developed a new approach to significantly improve the accuracy of RNA sequencing.

7 Feb 2024

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

6 Feb 2024

Study shines light on the role of transcription factors during early embryonic development

New international research shines a light on the role of transcription factors during early embryonic development.

6 Feb 2024

Gene News and Research

Latest Gene News and Research

COVID-19 may increase risk of pregnancy complications through placental DNA changes

New mouse model illuminates lung cancer's transformation into aggressive variant

Decoding the differences between two vital RNA transport complexes

ANU discovery provides new insight into how the immune system fights malaria

Never-before-documented genetic disorder causes rare lung disease

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Enzyme released by immune cells may play role in depression

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Study advances search for a blood test to identify disease-associated changes in the brain

Parental traits offer new clues to predicting neurodevelopmental disorders in children

New treatment target found for CDKL5 deficiency disorder

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

Immune cell networks key to success of personalized cancer treatment

New study sheds light on sex differences in allergic airway inflammation

New link between stress, immune system, and depression discovered

Researchers uncover how deadly MRSA pneumonia inhibits body's antimicrobial activity

Researchers develop new approach to improve the accuracy of RNA sequencing

Extra fingers and double hearts: Scientists decode how tiny mutations can derail development

Study shines light on the role of transcription factors during early embryonic development

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research