Gene News and Research

Latest Gene News and Research

Humans and mice have critical differences in gene responsible for DMD

Humans and mice have previously unknown and potentially critical differences in one of the genes responsible for Duchenne muscular dystrophy (DMD). Researchers writing in the open access journal BMC Biology have found that two major features of a key DMD gene are present in most mammals, including humans, but are specifically absent in mice and rats, calling into question the use of the mouse as the principal model animal for studying DMD.

4 Dec 2009

Findings suggest severity of atherosclerosis depends on the rate of white blood cell migration

By measuring the total gene activity in organs relevant for coronary artery disease (CAD), scientists at the Swedish medical university Karolinska Institutet have identified a module of genes that is important for the recruitment of white blood cells into the atherosclerotic plaque.

4 Dec 2009

Scientists discover mechanism by which E6 oncoprotein of high-risk HPV16 promotes carcinogenesis

In the 1980s, Harald zur Hausen and his co-workers discovered that specific types of human papillomavirus (HPV) cause cervical cancer. Scientists soon found out how these pathogens cause cells to degenerate. It is known today that the main culprits are viral proteins E6 and E7. Both proteins switch off different cellular control functions, thus promoting cell growth.

4 Dec 2009

Neurologix completes Phase 2 clinical trial of Parkinson’s study

Neurologix, Inc. (OTCBB:NRGX), a biotechnology company engaged in the development of innovative therapies for the brain and central nervous system, announced the completion of all planned surgeries in an ongoing Phase 2 clinical trial of the company’s gene transfer approach to the treatment of advanced Parkinson’s disease.

4 Dec 2009

Kyto advancing with a program for humanization of the mAbTCR23 antibody

Kyto Biopharma Inc., is a biotechnology company focused on developing monoclonal antibody and oligonucleotide targeting therapeutics based on a proprietary vitamin B12 platform for the treatment of various forms of cancer.

4 Dec 2009

Protein plays a key role in cancer and DNA repair

A protein that plays a key role in copying DNA also plays a vital role in repairing breaks in it, UC Davis scientists have found. The work is helping researchers understand how cancer cells can resist radiation and chemotherapy, as well as how cells become cancerous in the first place.

4 Dec 2009

Master gene linked to childhood brain tumor

The master gene Math1 is involved in the genesis of the most common childhood brain tumor, medulloblastoma, said researchers from Baylor College of Medicine (www.bcm.edu) in a report in the current issue of the journal Science.

4 Dec 2009

ISIS-FXIRx and ISIS-SMNRx included in Isis Pharmaceuticals' development pipeline

Isis Pharmaceuticals, Inc. announced today that it has added two new drugs to its development pipeline, ISIS-FXIRx and ISIS-SMNRx.

4 Dec 2009

Genetic differences determine intensity of people's responses to social rejection

Scientists have long known that opium-like painkillers, called opioids, relieve not only physical pain, but also some forms of emotional stress. Now, a new study reviewed by Faculty of 1000 Biology member Markus Heilig shows that small genetic differences in the gene for the opioid receptor can determine the intensity of people's responses to social rejection.

4 Dec 2009

Lightlake Therapeutics granted ethical approval for gene testing subjects in obesity treatment trial

After two decades of scientifically and medically proven success in their field, Lightlake Therapeutics' experts have been granted ethical approval to begin selecting and gene testing subjects for a trial of a simple, safe and effective treatment for what the World Health Organisation has described as a global epidemic of unhealthy eating and obesity.

3 Dec 2009

TGen scientists win $1,000 prize for best scientific paper presented at BIBM09

A team of scientists at the Translational Genomics Research Institute (TGen) won a $1,000 prize for best scientific paper presented at BIBM09, a premier bioinformatics and biomedicine conference.

3 Dec 2009

Children exposed to secondhand smoke face increased risk of lung cancer later in life

Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.

3 Dec 2009

Discovery of cell fibrous structure may provide clues to diagnose and treat medical disorders

Researchers from the Johns Hopkins Engineering in Oncology Center have shown that in healthy cells, a bundled "cap" of thread-like fibers holds the cell's nucleus, its genetic storehouse, in its proper place.

3 Dec 2009

Novel multi-analyte approach to develop urine-biomarker based diagnostic assay to be presented

Predictive Biosciences today announced that Company scientists will be presenting a novel multi-analyte approach to the development of a non-invasive, urine-biomarker based diagnostic assay during the 10th Annual Meeting of the Society of Urologic Oncology (SUO).

3 Dec 2009

Research study compares genetic make-up of humans and primates

In spite of their genetic similarity to humans, chimpanzees and great apes have maximum lifespans that rarely exceed 50 years. The difference, explains USC Davis School of Gerontology Professor Caleb Finch, is that as humans evolved genes that enabled them to better adjust to levels of infection and inflammation and to the high cholesterol levels of their meat rich diets.

3 Dec 2009

Manpei Suzuki Diabetes Foundation announces the 2009 winner of International Prize

The Manpei Suzuki Diabetes Foundation is pleased to announce the 2009 winner of the International Prize: Donald F. Steiner, MD, A. N. Pritzker Distinguished Service Professor Emeritus, Departments of Medicine and Biochemistry and Molecular Biology, The University of Chicago, USA.

3 Dec 2009

VARI scientists determine the structure of receptors that plants use to sense ABA

Van Andel Research Institute (VARI) researchers have determined precisely how the plant hormone abscisic acid (ABA) works at the molecular level to help plants respond to environmental stresses such as drought and cold.

3 Dec 2009

Study on the genetics of osteoarthritis

Interleukin Genetics, Inc. and NYU Langone Medical Center announced findings from a study performed in collaboration with Duke University on the genetics of osteoarthritis have been published this week in the "Online First" version of the Annals of Rheumatic Diseases and is available at http://ard.bmj.com/cgi/rapidpdf/ard.2009.113043v1.pdf.

2 Dec 2009

Vitro Diagnostics files a patent application for its technology related to generation of iPS cells

Vitro Diagnostics, Inc., dba Vitro Biopharma, announced the filing of a new United States patent application entitled “POU5-F1 Expression in Human Mesenchymal Stem Cells” and the development of new technology related to generation of human induced pluripotent stem cells (iPS).

2 Dec 2009

Development of novel virus can lead to new therapeutic strategy to combat cancer

Ohio State University cancer researchers have developed a tumor-attacking virus that both kills brain-tumor cells and blocks the growth of new tumor blood vessels.

2 Dec 2009

Gene News and Research

Latest Gene News and Research

Humans and mice have critical differences in gene responsible for DMD

Findings suggest severity of atherosclerosis depends on the rate of white blood cell migration

Scientists discover mechanism by which E6 oncoprotein of high-risk HPV16 promotes carcinogenesis

Neurologix completes Phase 2 clinical trial of Parkinson’s study

Kyto advancing with a program for humanization of the mAbTCR23 antibody

Protein plays a key role in cancer and DNA repair

Master gene linked to childhood brain tumor

ISIS-FXIRx and ISIS-SMNRx included in Isis Pharmaceuticals' development pipeline

Genetic differences determine intensity of people's responses to social rejection

Lightlake Therapeutics granted ethical approval for gene testing subjects in obesity treatment trial

TGen scientists win $1,000 prize for best scientific paper presented at BIBM09

Children exposed to secondhand smoke face increased risk of lung cancer later in life

Discovery of cell fibrous structure may provide clues to diagnose and treat medical disorders

Novel multi-analyte approach to develop urine-biomarker based diagnostic assay to be presented

Research study compares genetic make-up of humans and primates

Manpei Suzuki Diabetes Foundation announces the 2009 winner of International Prize

VARI scientists determine the structure of receptors that plants use to sense ABA

Study on the genetics of osteoarthritis

Vitro Diagnostics files a patent application for its technology related to generation of iPS cells

Development of novel virus can lead to new therapeutic strategy to combat cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering