Gene News and Research

Latest Gene News and Research

Most carriers of Fanconi anemia genes are not at a higher risk of cancer

For almost 50 years, Fanconi anemia has been associated with leukemia. Not just among those who have the genetic disorder but among their family members, whose genes, they were told, made them highly susceptible to a variety of malignancies.

13 Dec 2007

More regulatory DNA than previously thought

Surrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off.

13 Dec 2007

Discovery of key mechanism underlying idiopathic pulmonary fibrosis

A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment.

13 Dec 2007

Losses of long-established genes contribute to human evolution

While it is well understood that the evolution of new genes leads to adaptations that help species survive, gene loss may also afford a selective advantage.

13 Dec 2007

Researchers advance stem cell gene therapy

Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.

13 Dec 2007

Researchers find genetic switch for internal body clock

University of California, Irvine researchers have identified the chemical switch that triggers the genetic mechanism regulating our internal body clock.

13 Dec 2007

Variant of a tumor suppressor gene associated with aggressive prostate cancer

A variant of a tumor suppressor gene may be associated with an increased risk of aggressive prostate cancer, according to a study published online December 11 in the Journal of the National Cancer Institute.

13 Dec 2007

Cell-tracking software speeds drug development

Time is money, especially in the race to discover new anti-inflammatory drugs and bring them to market.

13 Dec 2007

Crimean Congo hemorrhagic fever virus strips away immune system's defensive measures

When the alert goes out that a virus has invaded the body, cells that have yet to be attacked prepare by "armoring" themselves for combat, attaching specific antiviral molecules to many of their own proteins to help resist the invader.

13 Dec 2007

Carbamazepine based drugs to include new advice for patients with Asian ancestry

The U.S. Food and Drug Administration today announced that the manufacturers of drugs containing the active ingredient carbamazepine have agreed to add to the drugs' labeling a recommendation that, before starting therapy with the drugs, patients with Asian ancestry get a genetic blood test that can identify a significantly increased risk of developing a rare, but serious, skin reaction.

13 Dec 2007

Lethal human H5N1 influenza virus Replikin gene still upregulated

Replikins Ltd. has announced its latest findings regarding the virus replikin count in human H5N1 influenza virus. The company's software-driven analysis has found that the prevalence of these sequences has remained high in Indonesia; in addition, higher counts now have been found in China.

12 Dec 2007

Epigenomic test that could improve treatment for specific gastric cancers

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center in a recent issue of Journal of Clinical Oncology identifies activation of the enzyme COX-2 in gastric cancer tumors as a prognostic indicator for poor outcome.

12 Dec 2007

When a female is attracted to a male some of her genes turn on and off

When a female is attracted to a male, entire suites of genes in her brain turn on and off, show biologists from The University of Texas at Austin studying swordtail fish.

10 Dec 2007

New model for neurodegeneration

The gradual loss of dopamine neurons is a hallmark of many neurodegenerative diseases - Parkinson's Disease chief among them.

10 Dec 2007

Silencing small but mighty cancer inhibitors

Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous.

10 Dec 2007

New studies on brain and behavior from the world's leading scientists

The 2007 American College of Neuropsychopharmacology Annual Meeting will feature hundreds of new studies on brain and behavior from the world's leading scientists.

10 Dec 2007

Keeping at-risk cells from developing cancer

Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes - in this case the inappropriate activation of a normally silent gene - develop by becoming addicted to certain growth factors.

10 Dec 2007

Growth factor receptor affects prostate cancer progression

Breeding mice with a gene for a cellular receptor that can be turned on and off-at will-not only enabled researchers at Baylor College of Medicine in Houston to show how prostate cancer progresses, but also provides a model for studying when a drug targeting a gene will have an effect on the cancer.

10 Dec 2007

Human evolution in genetic fast lane

Countering a common theory that human evolution has slowed to a crawl or even stopped in modern humans, a new study examining data from an international genomics project describes the past 40,000 years as a time of supercharged evolutionary change, driven by exponential population growth and cultural shifts.

10 Dec 2007