Gene News and Research

Latest Gene News and Research

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

Patients with a certain genetic variation who received the antiplatelet drug clopidogrel had a decreased platelet response to treatment and among those who had percutaneous coronary intervention (procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) had an increased risk of having a cardiovascular event in the following year than patients who did not have this variant, according to a study in the August 26 issue of JAMA.

25 Aug 2009

Research reveals the life-long detrimental impact of maternal smoking during pregnancy

A new study by researchers at the Keck School of Medicine of the University of Southern California (USC) has found that the life-long effects of maternal smoking during pregnancy may occur through specific changes in DNA patterns.

25 Aug 2009

New technique developed to identify gene copy number variations

A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive and accurate way of identifying gene copy number variations (CNVs).

25 Aug 2009

Researchers shed light on critical neurological process and mental retardation

With more than 1,500 eyes, not much escapes the fruit fly's sight. Now, a new research report in the journal GENETICS (http://www.genetics.org), describes how researchers from the United States and Ireland used those eyes to "see" new proteins necessary for memory.

25 Aug 2009

Phase I/II trial of Amphinex uses photochemical internalisation approach

PCI Biotech Holding ASA, the Norwegian drug delivery company focusing on effective delivery of cancer therapeutics, today announced that the first patient has received treatment in the Phase I/II trial with the lead candidate Amphinex(R), which uses a new approach called photochemical internalisation.

25 Aug 2009

UCLA finds link between high cholesterol and osteoporosis

A new UCLA study sheds light on the link between high cholesterol and osteoporosis and identifies a new way that the body's immune cells play a role in bone loss

25 Aug 2009

Researchers identify causative gene for features of 2q32q33 microdeletion syndrome

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24 Aug 2009

Curemark Founder delivers Industry Keynote address at Epigenomics Conference 2009

Curemark Founder and CEO Dr. Joan Fallon delivered the Industry Keynote address at the Third International Epigenomics, Sequencing 2009 Conference at Harvard Medical School on July 14th

24 Aug 2009

University of Michigan discovers new gene target for treating idiopathic pulmonary fibrosis

Researchers at the University of Michigan have discovered that targeting of a novel gene utilizing genetic and pharmacologic strategies was successful in treating pulmonary fibrosis in mice and will be developed for future testing in humans.

24 Aug 2009

Sigma-Aldrich scientists to leverage proprietary gene editing technology to develop genetically-engineered rodent research models

Sigma-Aldrich(R) (Nasdaq: SIAL) announced today that scientists at its new Sigma Advanced Genetic Engineering (SAGE(TM)) Labs in St. Louis will leverage its exclusive CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (www.compozrzfn.com) to define, develop and offer a new generation of genetically-engineered rodent research models. Such models are commonly used to study disease states in humans and play a key role in the drug discovery process.

24 Aug 2009

Research reveals that diarrheal bacteria can cause colon cancers

Johns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers. The investigators say that strains of the common Bacteroides fragilis (ETBF) dupe immune system cells into permitting runaway colon tissue inflammation, a precursor for malignant growth.

24 Aug 2009

Tiny filaments extending from cells may play a role in common malignant brain tumors

UCSF scientists have discovered that a tiny filament extending from cells, until recently regarded as a remnant of evolution, may play a role in the most common malignant brain tumor in children.

24 Aug 2009

Microbiologists discover new therapies for human respiratory syncytial virus and influenza A virus

A cellular molecule that not only can sense two common respiratory viruses but also can direct cells to mount a defense has been identified by microbiologists at The University of Texas Health Science Center at San Antonio.

24 Aug 2009

Research study links partial epilepsy to the disruption of brain development during early childhood

A form of partial epilepsy associated with auditory and other sensory hallucinations has been linked to the disruption of brain development during early childhood, according to a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC).

24 Aug 2009

New noninvasive technique to detect colorectal and gastric cancers found

A preliminary evaluation of methylation of two gene promoters in fecal DNA showed promise as a noninvasive method to detect colorectal and gastric cancers, according to a new study published online August 21 in the Journal of the National Cancer Institute.

24 Aug 2009

Gene discovery unveils a new protein that protects against hearing loss

Discovery of a deafness-causing gene defect in mice has helped identify a new protein that protects sensory cells in the ear, according to a study by University of Iowa and Kansas State University researchers. The findings appear in the August 21 issue of the open-access journal PLoS Genetics.

24 Aug 2009

Discovery of mutation in AIP gene associated with acromegaly

An indigenous family living in a mountainous area of Malaysian Borneo helped Van Andel Research Institute (VARI) researchers to discover information about genetic mutations associated with acromegaly, a form of gigantism that often results in enlarged hands, feet, and facial features.

24 Aug 2009

Ends of protein templates useful for arresting growth of cancerous cells

The tail ends of cellular protein templates, regions often thought relatively inconsequential, may actually play a role in preventing normal cells from becoming cancerous. The finding from scientists at Whitehead Institute for Biomedical research is reported in the August 20 edition of Cell.

21 Aug 2009

More evidence that genes increase a smokers' risk of lung cancer

Cancer Research UK funded scientists have confirmed that inherited changes in certain regions of the genome can increase a smokers' risk of developing lung cancer lung cancer, and determine the type of lung cancer that develops. Their results were published in this week's edition of the journal Cancer Research*.

21 Aug 2009

Role of HPRT genes detected in Lesch Nyan X-linked inherited disorders

A study from the Center for Molecular Genetics at the University of California, San Diego School of Medicine shows that a gene called HPRT plays an important role in setting the program by which primitive or precursor cells decide to become normal nerve cells in the human brain. This unconventional view of metabolic genes known as "housekeeping" genes is now online at the journal Molecular Therapy.

21 Aug 2009

Gene News and Research

Latest Gene News and Research

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

Research reveals the life-long detrimental impact of maternal smoking during pregnancy

New technique developed to identify gene copy number variations

Researchers shed light on critical neurological process and mental retardation

Phase I/II trial of Amphinex uses photochemical internalisation approach

UCLA finds link between high cholesterol and osteoporosis

Researchers identify causative gene for features of 2q32q33 microdeletion syndrome

Curemark Founder delivers Industry Keynote address at Epigenomics Conference 2009

University of Michigan discovers new gene target for treating idiopathic pulmonary fibrosis

Sigma-Aldrich scientists to leverage proprietary gene editing technology to develop genetically-engineered rodent research models

Research reveals that diarrheal bacteria can cause colon cancers

Tiny filaments extending from cells may play a role in common malignant brain tumors

Microbiologists discover new therapies for human respiratory syncytial virus and influenza A virus

Research study links partial epilepsy to the disruption of brain development during early childhood

New noninvasive technique to detect colorectal and gastric cancers found

Gene discovery unveils a new protein that protects against hearing loss

Discovery of mutation in AIP gene associated with acromegaly

Ends of protein templates useful for arresting growth of cancerous cells

More evidence that genes increase a smokers' risk of lung cancer

Role of HPRT genes detected in Lesch Nyan X-linked inherited disorders

eBook: Using iPSCs models for human disease research and drug discovery eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation