Gene News and Research

Latest Gene News and Research

Early life sun exposure linked to melanomas with BRAF gene mutations

Skin cancers often contain different gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery.

16 Jun 2007

Newer breast cancer drug may protect heart

By uncovering how one breast cancer drug protects the heart and another does not, Duke University Medical Center researchers believe they may have opened up a new way to screen drugs for possible heart-related side effects and to develop new drugs.

16 Jun 2007

Simple test predicts a person's risk for developing dementia within six years with 87 percent accuracy

The test, developed in the study by the researchers, is a 14-point index combining medical history, cognitive testing, and physical examination. It requires no special equipment and can be given in a clinical setting such as a doctor's office or at a patient's bedside.

16 Jun 2007

Scientists decode RNA mystery

A team of University of Maryland scientists have made a discovery that will help better direct drug therapies to their molecular targets.

15 Jun 2007

Structure of protein altered in autism revealed

As a result of mapping the structure of the protein complex implicated in autism spectrum disorders, a research team led by scientists at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences has discovered how particular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism.

15 Jun 2007

New genetic cause for Joubert syndrome

An international study by researchers at Seattle Children?s Hospital Research Institute, the University of Washington School of Medicine, and Radboud University in Nijmegen, Netherlands has identified a new genetic cause for Joubert syndrome (JS).

15 Jun 2007

Explanation for the random selection of X chromosome based on thermodynamics

A University of Warwick physicist has uncovered how female cells are able to choose randomly between their two X chromosomes and why that choice is always lucky.

15 Jun 2007

In vivo imaging of siRNA delivery and silencing in tumors

Using magnetic nanoparticles labeled with dye molecules, a team of investigators at the Massachusetts General Hospital has developed a delivery vehicle capable of transporting antitumor small interfering RNA (siRNA) molecules into cells.

14 Jun 2007

Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen

A detailed comparison of different types of ceramic nanoparticles has found that those made of silica can efficiently transport therapeutic genes to the spleen and trigger a potent immune response capable of attacking tumors.

14 Jun 2007

Nanoparticle-enabled peptide delivery triggers tumor regression

Cells possess a variety of ways of dealing with mutations that can cause them to grow uncontrollably and eventually form a tumor. The tumor suppressor gene p53 plays a critical role in these cancer prevention processes, largely by triggering a form a cell death known as apoptosis.

14 Jun 2007

Interfacing silicon nanowires with mammalian cells

A research team at the University of California, Berkeley, has achieved a significant step toward one of the futuristic goals of nanomedicine and nanobiology-developing technology for "wiring" together individual cells.

14 Jun 2007

Myelin and Huntington's disease

Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease.

14 Jun 2007

Thirteenth gene linked to Leber's congenital amaurosis

An international research team has discovered a gene that, when mutated, causes one of the most common forms of inherited blindness in babies.

14 Jun 2007

New genetic risk factor for coeliac disease

An international research consortium investigating the genetic causes of intestinal inflammatory conditions has identified a new genetic risk factor for coeliac disease.

14 Jun 2007

Cholesterol causes changes in gene expression

Experts from the University of Granada carried out research on atherosclerosis from its earliest stages to discover the origin of atheromatous plaques, fatty deposits gradually and irregularly formed in the main arteries, causing the narrowing of the blood vessel.

14 Jun 2007

What makes people susceptible to rheumatoid arthritis?

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life , the human genome , to figure out what makes these people susceptible to the disabling inflammatory condition.

14 Jun 2007

BRCA2 carriers more likely to develop aggressive and lethal prostate cancer

Carriers of a BRCA2 variation specific to Iceland are more likely to develop aggressive and lethal prostate cancer than noncarriers, according to a study published online in the Journal of the National Cancer Institute.

14 Jun 2007

Gamma-secretase acts as a tumor suppressor

Researchers at Burnham Institute for Medical Research (Burnham) have provided the first evidence that gamma-secretase, an enzyme key to the progression of Alzheimer's, acts as a tumor suppressor by altering the pathway of epidermal growth factor receptor (EGFR), a potential treatment target for cancer.

14 Jun 2007

FDA scrutinise companies selling human tissue

Following an inspection blitz by the Food and Drug Administration (FDA) on companies which handle a variety of human material from deceased donors, no serious problems have apparently been unearthed.

13 Jun 2007