Gene News and Research

Latest Gene News and Research

Seaweed symbionts reveal treasure trove of potential drug compounds

Marine macroalgae-associated Bacillota reveal a trove of bioactive compounds with potential pharmacological benefits, from antibacterial to anticancer properties. This comprehensive review illuminates the promising yet underexplored therapeutic applications of these marine microorganisms.

1 Nov 2023

New drug shows promise in killing cancer cells with genetic vulnerability

Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.

1 Nov 2023

Study finds epigenetic signature for obesity susceptibility in human twins

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

1 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk.

1 Nov 2023

3D organization of DNA can influence glioblastoma progression, study reveals

A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumor known as glioblastoma.

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

News-Medical sits down with Dr. Federico Dajas-Bailador, a leading expert in axon biology and drug discovery.

From ELRIG (UK) Ltd. 31 Oct 2023

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Broken String Biosciences today announced that its INDUCE-seq™ DNA break-mapping technology had been used in a peer-reviewed research paper to characterize off-target effects of CRISPR-Cas9 gene editing resulting from changes in DNA topology.

From Broken String Biosciences 31 Oct 2023

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, seizures, and cognitive disability.

30 Oct 2023

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

A new paper in The Lancet eBioMedicine explores whether these changes predict the future risk of stomach tumors and how epigenetic changes interact with environmental and lifestyle factors in this process.

30 Oct 2023

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Canadian researchers develop a cell-free DNA-based multimodal assay for early cancer detection in patients with Li-Fraumeni Syndrome, a high-cancer-risk condition. The assay outperforms conventional methods, promising more sensitive and less invasive cancer surveillance.

29 Oct 2023

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

Mature spermatozoa are characterized by an head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit "Life & Health" at the University of Bonn have found that a loss of the structural protein ACTL7B blocks spermatogenesis in male mice.

27 Oct 2023

Gene News and Research

Latest Gene News and Research

Seaweed symbionts reveal treasure trove of potential drug compounds

New drug shows promise in killing cancer cells with genetic vulnerability

Study finds epigenetic signature for obesity susceptibility in human twins

New gene editing method creates first mice with human-like COVID-19

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

3D organization of DNA can influence glioblastoma progression, study reveals

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

Sickle cell disease patients willing to accept high risks for gene therapy cure

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

New drug gets FDA approval for the treatment of common genetic disease in young boys

Osteoarthritis may be treatable and reversible, new study shows

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

New MECP2 gene variant identified and characterized in Rett syndrome

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research