Gene News and Research

Latest Gene News and Research

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

21 Jul 2022

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

The University of Texas MD Anderson Cancer Center and Obsidian Therapeutics, Inc. today announced Food and Drug Administration (FDA) clearance of an Investigational New Drug (IND) application for an MD Anderson-sponsored Phase I clinical study of OBX-115, Obsidian's lead engineered tumor infiltrating lymphocyte (TIL) therapy candidate.

21 Jul 2022

Pigment epithelium-derived factor ablations may lead to eye aging

Researchers identified that loss of pigment epithelium-derived factor (PEDF) may cause aging in the eye.

21 Jul 2022

Parents become drug developers to save their children’s lives

Maggie Carmichael wasn't developing like other kids. As a toddler, she wasn't walking and had a limited vocabulary for her age.

21 Jul 2022

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.

21 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Benefits of physical, mental activity on thinking may vary for men and women, study suggests

Studies have shown that physical and mental activity help preserve thinking skills and delay dementia. A new study suggests that these benefits may vary for men and women.

20 Jul 2022

Scientists find a promising new combination therapy for certain types of lung tumors

Scientists at the Francis Crick Institute have found that using immunotherapy alongside a drug that blocks a common gene mutation in lung cancer could be a promising new combination therapy for certain types of lung tumors.

20 Jul 2022

Study finds white adipose tissue to be the most vulnerable organ to obesity-related metabolic changes

When the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some organs or tissues are more sensitive to metabolic stress.

20 Jul 2022

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Genes and lifestyle factors together play a role in stroke risk. However, even for people at high risk for stroke, adopting a healthy cardiovascular lifestyle may significantly lower the risk of stroke in their lifetime, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Jul 2022

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

Researchers reported mutations in SARS-CoV-2 Delta and Omicron variants of concern infection cases treated with neutralizing monoclonal antibodies.

20 Jul 2022

Review: No clear evidence that serotonin levels are responsible for depression

After decades of study, there remains no clear evidence that serotonin levels or serotonin activity are responsible for depression, according to a major review of prior research led by UCL scientists.

20 Jul 2022

Study shows Omicron BA.4/5 infection triggers highly cross-reactive neutralizing antibodies

Researchers compared the levels of cross-reactive neutralizing antibodies elicited by SARS-CoV-2 Omicron BA.4 and BA.1 infections.

20 Jul 2022

Machine learning models help forecast immunotherapy response from gut microbiomes

A new research paper was published in Oncotarget on July 19, 2022, entitled, "Predicting cancer immunotherapy response from gut microbiomes using machine learning models."

20 Jul 2022

Scientists find new evidence against using BET inhibitors to treat COVID-19

A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

20 Jul 2022

Scientists show how lymphatics are associated with microglia and brain development in zebrafish

During the embryonic stage of brain development, some neurons and synapses form properly and connect, but others don't, causing some parts and pieces to be discarded.

19 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

$Braces could be a total game-changer for young children with thighbone fractures$

Braces could be a total game-changer for young children with thighbone fractures

For decades, the treatment for a young child with a broken femur has been the same: a surgically placed spica cast, commonly known as a body cast. But now, thanks to a new study led by Children's Hospital Los Angeles, the days of casting these injuries may soon be over.

19 Jul 2022

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

19 Jul 2022

Gene News and Research

Latest Gene News and Research

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

Pigment epithelium-derived factor ablations may lead to eye aging

Parents become drug developers to save their children’s lives

Study offers insight into the basic cellular pathologies driving interstitial lung disease

Is monkeypox a global public-health emergency?

Benefits of physical, mental activity on thinking may vary for men and women, study suggests

Scientists find a promising new combination therapy for certain types of lung tumors

Study finds white adipose tissue to be the most vulnerable organ to obesity-related metabolic changes

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

Review: No clear evidence that serotonin levels are responsible for depression

Study shows Omicron BA.4/5 infection triggers highly cross-reactive neutralizing antibodies

Machine learning models help forecast immunotherapy response from gut microbiomes

Scientists find new evidence against using BET inhibitors to treat COVID-19

Scientists show how lymphatics are associated with microglia and brain development in zebrafish

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

Identifying a core human microbiome

Braces could be a total game-changer for young children with thighbone fractures

Study shows how a critical Lassa virus protein drives infection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging