Gene News and Research

Latest Gene News and Research

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

Researchers evaluated the neutralizing ability of sera from COVID-19 patients.

27 Jun 2022

Chemically modified rocaglates have a stronger effect against viral replication

Hepatitis E virus (HEV) is widespread, and so far there is no effective drug. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses.

27 Jun 2022

Specific gene mutations may be responsible for how long someone lives with Parkinson's disease

How long someone lives with Parkinson's disease may be down to specific gene mutations, according to new research presented today at the 8th European Academy of Neurology Congress.

26 Jun 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

Mapping the trajectory of SARS-CoV-2 evolution inside the host

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States mapped the trajectory of within-host evolution of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

24 Jun 2022

New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

The original SARS-CoV-2 viral strain that emerged in early 2020 was able to latch on to sugars known as sialic acids, found on the surface of human cells, an ability that later strains did not retain.

24 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

"Founder events" that reduced genetic diversity found to be common throughout human history

Human populations have waxed and waned over the millennia, with some cultures exploding and migrating to new areas or new continents, others dropping to such low numbers that their genetic diversity plummeted.

23 Jun 2022

Newly identified gene may be responsible for sex-linked effects on women's heart disease outcomes

When diagnostic tests for the heart were first created, scientists at the time did not fully consider that no two bodies are the same, especially between the sexes.

23 Jun 2022

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Breast cancers with HER2 mutations respond to the drug neratinib, but the responses are variable and often not durable.

23 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families.

23 Jun 2022

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.

23 Jun 2022

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.

23 Jun 2022

Gene News and Research

Latest Gene News and Research

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

Chemically modified rocaglates have a stronger effect against viral replication

Specific gene mutations may be responsible for how long someone lives with Parkinson's disease

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Scientists identify new genetic disease that delays children's intellectual development

Mapping the trajectory of SARS-CoV-2 evolution inside the host

New molecular information could help develop more effective treatments for melanoma

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

"Founder events" that reduced genetic diversity found to be common throughout human history

Newly identified gene may be responsible for sex-linked effects on women's heart disease outcomes

New method helps unravel three-dimensional structure of the human genome

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Study unveils a precise model for the stinging organelle of starlet sea anemone

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

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