Gene News and Research

Latest Gene News and Research

Chemical-based sequencing method to efficiently study DNA methylation

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off.

1 Jul 2022

Brigham receives $16 million Helmsley Charitable Trust grant to improve healthcare delivery for NCDs

Brigham and Women's Hospital announces a $16 million grant from The Leona M. and Harry B. Helmsley Charitable Trust to support the implementation and evaluation of an integrated service delivery model (PEN-Plus) for severe chronic noncommunicable diseases (NCDs) such as type 1 diabetes, rheumatic heart disease, cardiomyopathies, and sickle cell disease in eight low- and lower-middle-income countries in sub-Saharan Africa and South Asia.

1 Jul 2022

Cancer drug helped delay progression of Duchenne muscular dystrophy in mice

Researchers at UBC’s School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy.

1 Jul 2022

Scientists prove the “neuroprotective” function of p62 protein in a mouse model

Neurodegenerative diseases like Alzheimer’s and Parkinson’s are defined by pathogenic accumulation of toxic proteins in the brain.

1 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

New study investigates the epigenetic drift of time passing

A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, "Time makes histone H3 modifications drift in mouse liver."

30 Jun 2022

Rice lab’s microbial community profiling software effectively identifies bacterial species

Part of a gene is better than none when identifying a species of microbe. But for Rice University computer scientists, part was not nearly enough in their pursuit of a program to identify all the species in a microbiome.

30 Jun 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

Study uncovers new gene that increases Alzheimer's disease risk in women

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S. Scientists have discovered some genetic variants that increase the risk for developing Alzheimer's; the most well-known of these for people over the age of 65 is the APOE ε4 allele.

30 Jun 2022

The severity of Omicron BA.4/BA.5 lineages in the South Africa population

Researchers assessed the clinical severity of SARS-CoV-2 Omicron variants.

30 Jun 2022

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

A research team from the LKS Faculty of Medicine, The University of Hong Kong discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications.

30 Jun 2022

SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Existing cancer drug shows promise for treating patients with muscular dystrophy

Researchers at the University of British Columbia's School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy.

29 Jun 2022

Online version of algorithm shows how biases in RNA sequences affect gene expression

A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.

29 Jun 2022

NUS researchers discover a new way to interpret unsolved Mendelian diseases

The development of an embryo is a well-orchestrated string of processes, ensuring correct formation and positioning of vital organs of the growing organism.

29 Jun 2022

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Researchers evaluated the distribution of microbes on surfaces within a microbiology laboratory.

29 Jun 2022

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Researchers assessed the impact of SARS-CoV-2 envelope protein on the bromodomain and extraterminal domain (BET) proteins.

29 Jun 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

Gene News and Research

Latest Gene News and Research

Chemical-based sequencing method to efficiently study DNA methylation

Brigham receives $16 million Helmsley Charitable Trust grant to improve healthcare delivery for NCDs

Cancer drug helped delay progression of Duchenne muscular dystrophy in mice

Scientists prove the “neuroprotective” function of p62 protein in a mouse model

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

New study investigates the epigenetic drift of time passing

Rice lab’s microbial community profiling software effectively identifies bacterial species

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Study uncovers new gene that increases Alzheimer's disease risk in women

The severity of Omicron BA.4/BA.5 lineages in the South Africa population

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

SARS-CoV-2 3CLpro also susceptible to mutations

Existing cancer drug shows promise for treating patients with muscular dystrophy

Online version of algorithm shows how biases in RNA sequences affect gene expression

NUS researchers discover a new way to interpret unsolved Mendelian diseases

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Complex molecular dance could inform the development of future treatments for fragile X syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting