Gene News and Research

Latest Gene News and Research

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Key immunological changes that support peanut allergy remission in children discovered

Australian researchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more targeted treatments.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Seven healthy habits may lower the risk of dementia in people with high genetic risk

Seven healthy habits and lifestyle factors may play a role in lowering the risk of dementia in people with the highest genetic risk, according to research published in the May 25, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

25 May 2022

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

Lowering blood glucose levels could improve fertility in females with obesity

Reproductive hormone levels in females with obesity may be partially restored by lowering blood glucose levels, leading to improved fertility, according to a study published in the Journal of Endocrinology.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Distinct maternal signals rhythmically control a variety of neuronal processes, study finds

During fetal development, before the biological clock starts ticking on its own, genes within the fetus's developing clock respond to rhythmic behavior in the mother, according to a new study publishing May 24th in the open-access journal PLOS Biology by Alena Sumová and colleagues of the Czech Academy of Sciences in Prague. The findings contribute to our understanding of the development of the internal clock, and may have implications for the treatment of premature babies.

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Study identifies a gene that plays an important role in embryo development

A new study co-led by a Cedars-Sinai investigator identified a gene that plays an important role in a biological pathway involved in embryo development.

24 May 2022

Study reveals how processes in the human body could turn harmless immune cells into ruthless killers

Processes in the human body could turn groups of harmless immune cells into ruthless killers, capable of attacking other cells infected with viruses or parasites, and potentially tumor cells, a new study reveals.

24 May 2022

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Researchers assessed the neutralization efficacy of a saRNA vaccine targeting SARS-CoV-2 S protein against reinfection among hamsters with prior vaccination or infection.

24 May 2022

Characterizing spillover dynamics and global transmission patterns of avian influenza A viruses

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24 May 2022

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.

24 May 2022

Study sheds light on the molecular biology behind genetic epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question – it could also curb the functioning of several closely related proteins.

23 May 2022

Gene News and Research

Latest Gene News and Research

The role of pyroptosis in COVID-19

Researchers identify the genetic causes of three mitochondrial diseases using new approach

Key immunological changes that support peanut allergy remission in children discovered

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Seven healthy habits may lower the risk of dementia in people with high genetic risk

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

Lowering blood glucose levels could improve fertility in females with obesity

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Distinct maternal signals rhythmically control a variety of neuronal processes, study finds

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Study unveils the novel driver of cardiomyocyte loss

Hydration restores airway integrity in people with cystic fibrosis

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Study identifies a gene that plays an important role in embryo development

Study reveals how processes in the human body could turn harmless immune cells into ruthless killers

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Characterizing spillover dynamics and global transmission patterns of avian influenza A viruses

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

Study sheds light on the molecular biology behind genetic epilepsy

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting