Gene News and Research

Latest Gene News and Research

Machine learning and proteomics predict cardiovascular risk more accurately

An innovative proteomics-based model that predicts the risk of cardiovascular events with higher accuracy than current clinical models.

10 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

MOFs could help improve the delivery of genetic cargo into target cells

Hybrid material helps ferry genetic cargo to target cells. An emerging type of material called a metal-organic framework(MOF) could help improve the delivery of genetic material for treating disease.

10 Apr 2022

Preliminary data from clinical trial reveals safety, efficacy of new CAR T-cell therapy for solid tumors

A new chimeric antigen receptor (CAR) T-cell product had an acceptable safety profile and showed early signs of efficacy as a monotherapy and in combination with an mRNA vaccine in patients with solid tumors, according to preliminary data from a phase I/II clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

8 Apr 2022

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

UNSW researchers have used CRISPR gene editing – a type of 'molecular scissors' – to understand how deletions in one area of the genome can affect the expression of nearby genes.

8 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Researchers develop new method to ‘time jump’ skin cells by 30 years

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function.

8 Apr 2022

Large-scale study sheds more light on the genetic basis of schizophrenia

What is the role of genetics in schizophrenia? To address this question, an international group of researchers led by Charité – Universitätsmedizin Berlin and Cardiff University developed and conducted the largest-ever genetic study on schizophrenia.

7 Apr 2022

SARS-CoV-2 detected using smartphone biosensor

Researchers describe the use of RT-LAMP in combination with particle diffusometry to detect SARS-CoV2 in saliva samples.

7 Apr 2022

Mutant mice with a human gene variant exhibits ADHD-like problems

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

7 Apr 2022

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

7 Apr 2022

UC researcher awarded renewal grant to continue the study of genetic drivers of breast cancer

A grant renewal for a University of Cincinnati researcher will help continue the study of genetic drivers of breast cancer and potential therapeutic targets.

7 Apr 2022

Researchers obtain a treasure trove of new data about RNA viruses from ocean water samples

Ocean water samples collected around the world have yielded a treasure trove of new data about RNA viruses, expanding ecological research possibilities and reshaping our understanding of how these small but significant submicroscopic particles evolved.

7 Apr 2022

Study investigates biochemical, biophysical, and immunological profile of COVID-19 respiratory secretions

A new study assessed the biophysical, immunological, and biochemical characteristics of respiratory secretions in acute SARS-CoV-2 infections.

7 Apr 2022

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.

7 Apr 2022

Gene News and Research

Latest Gene News and Research

Machine learning and proteomics predict cardiovascular risk more accurately

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

MOFs could help improve the delivery of genetic cargo into target cells

Preliminary data from clinical trial reveals safety, efficacy of new CAR T-cell therapy for solid tumors

Researchers seek to understand how microbes in the GI tract help people resist pathogens

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

City of Hope's late-breaking clinical trial data to be presented at AACR

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Researchers develop new method to ‘time jump’ skin cells by 30 years

Large-scale study sheds more light on the genetic basis of schizophrenia

SARS-CoV-2 detected using smartphone biosensor

Mutant mice with a human gene variant exhibits ADHD-like problems

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

UC researcher awarded renewal grant to continue the study of genetic drivers of breast cancer

Researchers obtain a treasure trove of new data about RNA viruses from ocean water samples

Study investigates biochemical, biophysical, and immunological profile of COVID-19 respiratory secretions

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

The dynamics of the Omicron wave in England

Insights into the pathogenesis of the previous and circulating SARS-CoV-2 variants in mice

Transcriptional reprogramming of monocytes in COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging