Gene News and Research

Latest Gene News and Research

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

3 Apr 2022

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

1 Apr 2022

Study offers insights into the long-term impacts of weight-loss diets and food insecurity

Could fluctuations in body weight resulting from drastically cutting and increasing calories lead to physiological changes that raise the risk of heart disease or diabetes later in life?

1 Apr 2022

Research illuminates why immune disorders affect only one of two identical twins

Scientists have long queried the causes of immune disorders in only one of two identical twins with identical genes. New research from the Wellcome Sanger Institute, the Josep Carreras Leukaemia Research Institute in Spain and their collaborators, has found the answer lies in both alterations in immune cell-cell communication and the epigenome, the host of biological processes that regulate how our genes function.

1 Apr 2022

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

In a new study, researchers developed a whole-genome sequencing pipeline based on nanopore technology for the rapid identification of genetic variants.

1 Apr 2022

UMass Amherst research focuses on the benefits of consuming mushrooms

Next time you order a pizza or whip up a creamy risotto, go ahead and load on the mushrooms.

31 Mar 2022

Therapeutic antibodies against filoviruses including Ebola and Marburg

Researchers discuss the development and structural characterization of therapeutic monoclonal antibodies targeting the surface glycoprotein of filoviruses.

31 Mar 2022

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

UW Medicine genome scientists were among the leading contributors to the publication of the first complete, gapless sequence of a human genome announced this week by the National Human Genome Research Institute.

31 Mar 2022

Novaplex real-time PCR assays can reliably, rapidly detect SARS-CoV-2 in patient samples

A new study has found that the Novaplex SARS-CoV-2 Variant I, II, and IV real-time PCR assays (from Seegene Technology) can reliably detect SARS-CoV-2 in patient samples and identify known variants of interest and concern.

31 Mar 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Study identifies a set of sporadic genetic mutations behind cavernous angioma

A rare type of brain blood vessel malformation known as a cavernous angioma affects more than one million Americans and carries a lifetime risk of stroke and seizures.

30 Mar 2022

Decisive role of PDK1 enzyme in acute myeloid leukemia revealed

Acute myeloid leukemia (AML) remains harder to treat therapeutically due to the high existing genetic heterogeneity not only between patients but also between the population of subclones of cancer cells within the same person.

30 Mar 2022

Research provides a roadmap for new therapies to treat chorioamnionitis

One of the serious complications that can occur during late pregnancy happens when the amniotic sac (also called the bag of waters) breaks too early, which can allow bacterial infections to cause dangerous tissue inflammation around the placenta.

30 Mar 2022

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

COMBINEDBrain puts advocacy groups in the driver's seat in the race to cure rare neurodevelopmental diseases. Patient advocacy foundations representing more than thirty rare genetic neurodevelopmental disorders join forces as part of COMBINEDBrain to make it faster to do research on their disorders.

30 Mar 2022

Researchers discover potential link between inflammation and structure of specific brain regions

A potential link between inflammation and the structure of specific regions of the brain has been identified by researchers at the University of Birmingham.

30 Mar 2022

$1.4 million grant bolsters UC San Diego scientists' efforts to fight malaria spread

Scientists at the University of California San Diego are hard at work on new genetic technologies intended for use in curbing mosquito populations, fighting the spread of malaria and mitigating the hazards associated with the deployment of gene-editing systems in the wild.

30 Mar 2022

Gene News and Research

Latest Gene News and Research

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Study offers insights into the long-term impacts of weight-loss diets and food insecurity

Research illuminates why immune disorders affect only one of two identical twins

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

UMass Amherst research focuses on the benefits of consuming mushrooms

Therapeutic antibodies against filoviruses including Ebola and Marburg

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

Novaplex real-time PCR assays can reliably, rapidly detect SARS-CoV-2 in patient samples

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Study identifies a set of sporadic genetic mutations behind cavernous angioma

Decisive role of PDK1 enzyme in acute myeloid leukemia revealed

Research provides a roadmap for new therapies to treat chorioamnionitis

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

Researchers discover potential link between inflammation and structure of specific brain regions

$1.4 million grant bolsters UC San Diego scientists' efforts to fight malaria spread

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research